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Karyopherin alpha 5 (Importin alpha 6) Proteins (KPNA5)

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Additionally we are shipping KPNA5 Antibodies (70) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse KPNA5 KPNA5 16650 O35345
KPNA5 3841 O15131
KPNA5 294392 Q56R16
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Top KPNA5 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,529.17
Details

KPNA5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

More Proteins for Karyopherin alpha 5 (Importin alpha 6) (KPNA5) Interaction Partners

Mouse (Murine) Karyopherin alpha 5 (Importin alpha 6) (KPNA5) interaction partners

  1. Data shows that Importin 7 (show IPO7 Proteins) binds many partners from ovary that alpha are involved in RNA processing, chromosome organization, and chromatin modification.

  2. Importin alpha7 is a new member of the small group of maternal effect genes.

  3. Overexpression of Kpna6 (show KPNA6 Proteins) facilitates Keap1 (show KEAP1 Proteins) nuclear import and attenuates Nrf2 (show NFE2L2 Proteins) signaling, whereas knockdown of Kpna6 (show KPNA6 Proteins) slows down Keap1 (show KEAP1 Proteins) nuclear import and enhances the Nrf2 (show NFE2L2 Proteins)-mediated adaptive response induced by oxidative stress.

Human Karyopherin alpha 5 (Importin alpha 6) (KPNA5) interaction partners

  1. BIG3 (show WDR5 Proteins) may block the KPNAs (KPNA1 (show KPNA1 Proteins), KPNA5, and KPNA6 (show KPNA6 Proteins)) binding region(s) of PHB2 (show PHB2 Proteins).

  2. eVP24 recognizes a unique nonclassical nuclear localization signal binding site on KPNA5 that is necessary for efficient phosphoryated STAT1 (show STAT1 Proteins) nuclear transport.

  3. Study identified the sequences KKKRR, KKKRK, and KKRKK as the optimal sequences for binding to this site for mouse importin (show KPNA4 Proteins)-alpha2, human importin (show KPNA4 Proteins)-alpha1, and human importin (show KPNA4 Proteins)-alpha5, respectively.

KPNA5 Protein Profile

Protein Summary

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion\; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA5 protein belongs to the importin alpha protein family and is thought to be involved in NLS-dependent protein import into the nucleus.

Gene names and symbols associated with KPNA5

  • karyopherin (importin) alpha 6 (Kpna6)
  • karyopherin alpha 5 (importin alpha 6) (kpna5)
  • karyopherin alpha 5 (importin alpha 6) (KPNA5)
  • karyopherin alpha 5 (importin alpha 6) (Kpna5)
  • im:7151662 protein
  • Ipoa6 protein
  • IPOA7 protein
  • Kpna5 protein
  • NPI-2 protein
  • SRP6 protein
  • zgc:110662 protein

Protein level used designations for KPNA5

importin alpha-S2 , importin subunit alpha-7 , karyopherin (importin) alpha 5 , karyopherin subunit alpha-6 , importin subunit alpha-6 , karyopherin subunit alpha-5 , importin alpha 6

GENE ID SPECIES
16650 Mus musculus
553205 Danio rerio
421738 Gallus gallus
3841 Homo sapiens
397220 Sus scrofa
783596 Bos taurus
294392 Rattus norvegicus
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