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Karyopherin alpha 6 (Importin alpha 7) Proteins (KPNA6)

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. Additionally we are shipping KPNA6 Antibodies (36) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KPNA6 16650 O35345
KPNA6 23633 O60684
Rat KPNA6 KPNA6 362607  
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Top KPNA6 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

KPNA6 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Karyopherin alpha 6 (Importin alpha 7) (KPNA6) Interaction Partners

Mouse (Murine) Karyopherin alpha 6 (Importin alpha 7) (KPNA6) interaction partners

  1. Data shows that Importin 7 (show IPO7 Proteins) binds many partners from ovary that alpha are involved in RNA processing, chromosome organization, and chromatin modification.

  2. Importin alpha7 is a new member of the small group of maternal effect genes.

  3. Overexpression of Kpna6 facilitates Keap1 (show KEAP1 Proteins) nuclear import and attenuates Nrf2 (show NFE2L2 Proteins) signaling, whereas knockdown of Kpna6 slows down Keap1 (show KEAP1 Proteins) nuclear import and enhances the Nrf2 (show NFE2L2 Proteins)-mediated adaptive response induced by oxidative stress.

Human Karyopherin alpha 6 (Importin alpha 7) (KPNA6) interaction partners

  1. BIG3 (show WDR5 Proteins) may block the KPNAs (KPNA1 (show KPNA1 Proteins), KPNA5 (show KPNA5 Proteins), and KPNA6) binding region(s) of PHB2 (show PHB2 Proteins).

  2. Bel1 fragment with residues 215-223, which bears the NLS (show ALDH1A2 Proteins), interacts with KPNA1 (show KPNA1 Proteins), KPNA6, and KPNA7.

  3. Importin alpha1 and alpha7 are positive regulators of human-like polymerase activity and pathogenicity beyond their role in nuclear transport.

  4. Overexpression of KPNA6 facilitates KEAP1 (show KEAP1 Proteins) nuclear import and attenuates NRF2 (show GABPA Proteins) signaling, whereas knockdown of KPNA6 slows down KEAP1 (show KEAP1 Proteins) nuclear import and enhances the NRF2 (show GABPA Proteins)-mediated adaptive response induced by oxidative stress.

  5. Importin (show KPNA4 Proteins) alpha5 and alpha7 bind to Stat3 (show STAT3 Proteins) upon cytokine stimulation.

KPNA6 Protein Profile

Protein Summary

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.

Gene names and symbols associated with KPNA6

  • karyopherin alpha 6 (importin alpha 7) (KPNA6)
  • karyopherin (importin) alpha 6 (Kpna6)
  • karyopherin alpha 6 (importin alpha 7) (Kpna6)
  • karyopherin alpha 6 (importin alpha 7) (kpna6)
  • IPOA7 protein
  • Kpna5 protein
  • KPNA7 protein
  • NPI-2 protein

Protein level used designations for KPNA6

karyopherin alpha 6 (importin alpha 7) , importin subunit alpha-7-like , importin alpha-S2 , importin subunit alpha-7 , karyopherin (importin) alpha 5 , karyopherin subunit alpha-6 , importin alpha 7 subunit , importin-alpha-S2 , karyopherin (importin) alpha 6 , imp alpha 5 , importin alpha 5.2 protein , Importin subunit alpha-7

GENE ID SPECIES
100386067 Callithrix jacchus
16650 Mus musculus
23633 Homo sapiens
487314 Canis lupus familiaris
397539 Sus scrofa
531602 Bos taurus
362607 Rattus norvegicus
407836 Xenopus laevis
419656 Gallus gallus
100172333 Pongo abelii
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