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The protein encoded by KRT1 is a member of the keratin gene family. Additionally we are shipping KRT1 Kits (13) and KRT1 Proteins (11) and many more products for this protein.
Showing 10 out of 112 products:
Human Monoclonal KRT1 Primary Antibody for ICC, IHC (fro) - ABIN251201
Boelsma, Gibbs, Faller, Ponec: Characterization and comparison of reconstructed skin models: morphological and immunohistochemical evaluation. in Acta dermato-venereologica 2000
Show all 9 references for ABIN251201
Human Polyclonal KRT1 Primary Antibody for IHC, IHC (p) - ABIN4302278
Gallotta, Gancitano, Pietrocola, Mora, Pezzicoli, Tuscano, Chiarot, Nardi-Dei, Taddei, Rindi, Speziale, Soriani, Grandi, Margarit, Bensi: SpyAD, a moonlighting protein of group A Streptococcus contributing to bacterial division and host cell adhesion. in Infection and immunity 2014
Show all 2 references for ABIN4302278
Human Polyclonal KRT1 Primary Antibody for FACS, IHC (p) - ABIN653648
Labudova, Tomaskova, Skultety, Pastorek, Pastorekova: The nucleoprotein of lymphocytic choriomeningitis virus facilitates spread of persistent infection through stabilization of the keratin network. in Journal of virology 2009
Show all 2 references for ABIN653648
Human Polyclonal KRT1 Primary Antibody for IHC (fro), IF - ABIN126064
Than, Sumegi, Than, Kispal, Bohn: Cloning and sequencing of human oncodevelopmental soluble placental tissue protein 17 (PP17): homology with adipophilin and the mouse adipose differentiation-related protein. in Tumour biology 1999
Show all 2 references for ABIN126064
Human Polyclonal KRT1 Primary Antibody for FACS, IHC (p) - ABIN951809
Barcelos, Sotto: Comparative analysis of the expression of cytokeratins (1, 10, 14, 16, 4), involucrin, filaggrin and e-cadherin in plane warts and epidermodysplasia verruciformis plane wart-type lesions. in Journal of cutaneous pathology 2009
Show all 2 references for ABIN951809
Cat (Feline) Monoclonal KRT1 Primary Antibody for IHC (fro), IHC (p) - ABIN259965
Nautscher, Bauer, Steffl, Amselgruber: Comparative morphological evaluation of domestic animal cornea. in Veterinary ophthalmology 2016
Dog (Canine) Polyclonal KRT1 Primary Antibody for IHC, WB - ABIN2775333
Schweizer, Bowden, Coulombe, Langbein, Lane, Magin, Maltais, Omary, Parry, Rogers, Wright: New consensus nomenclature for mammalian keratins. in The Journal of cell biology 2006
Report genetic/clinical spectrum of KRT1 mutations in keratinopathic ichthyosis (show LBR Antibodies).
demonstrated the presence of a genetic cutaneous mosaicism. Both patients carry the KRT1 pI479T substitution, but in the palmoplantar areas of one of them, only the mutated allele is expressed (hemizygous). This leads to highlight a new type of cutaneous mosaic, the palmoplantar mosaicism
In our study, the missense mutation in the proband and his mother with epidermolytic ichthyosis (show LBR Antibodies) was a single amino acid difference in codon 478, which causes more serious skin manifestations
Complete structure of an epithelial keratin 1/keratin 10 (show KRT10 Antibodies) dimer has been presented.
These findings indicate that exogenous FABP4 (show FABP4 Antibodies) interacts with plasma membrane proteins, specifically CK1 (show CSNK1A1L Antibodies).
analysis of a heterozygous novel splice junction mutation in the 2B domain of KRT1 in a family with diffuse palmoplantar keratoderma
In ichthyosis (show LBR Antibodies) with confetti, a causal de novo KRT1 mutation had a C-terminal frameshift, replacing 22 C-terminal AAs (show FGD1 Antibodies) with an alternate 30-AA peptide. It distorted the IF network and mislocalized to the nucleus. Reversion occurred by mitotic recombination.
In HeLa cells transiently expressing C2GnT-M (show GCNT3 Antibodies)-GFP, knockdown of KRT1 does not affect Golgi morphology but leaves C2GnT-M (show GCNT3 Antibodies) outside of the Golgi, resulting in the formation of sialyl-T antigen.
Decreased levels of cytokeratin-1 is associated with breast cancer.
Hsp74 (show HSPA9 Antibodies), a potential bladder cancer marker, has direct interaction with keratin 1.
SCF (show KITLG Antibodies) improves diabetic wound healing in part by increasing the recruitment of a unique stem cell population present in the skin.
Absence of Krt1 caused a prenatal increase in interleukin-18 (IL-18 (show IL18 Antibodies)) and the S100A8 (show S100A8 Antibodies) and S100A9 (show S100A9 Antibodies) proteins, accompanied by a barrier defect and perinatal lethality.
The Krt1(-/-);Krt10 (show KRT10 Antibodies)(-/-) mice showed premature loss of nuclei during epidermal differentiation and lower levels of emerin (show EMD Antibodies), lamin A/C (show LMNA Antibodies) and Sun1 (show SUN1 Antibodies), revealing a previously unknown function for IFs in maintaining nuclear integrity in the upper epidermis.
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
, cytokeratin VI (human cytokeratin 10)
, cytokeratin Ia (human cytokeratin 1, epidermolytic hyperkeratosis)
, 67 kDa cytokeratin
, cytokeratin 1
, epidermolytic hyperkeratosis 1
, hair alpha protein
, keratin, type II cytoskeletal 1
, type-II keratin Kb1
, keratin 86
, keratin complex 2, basic, gene 1
, type II keratin Kb1
, epithelial keratin 1
, epithelial keratin-1
, keratin 1 (epidermolytic hyperkeratosis)
, Keratin, type II cytoskeletal 1