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The protein encoded by KRT23 is a member of the keratin family. Additionally we are shipping Keratin 23 Antibodies (77) and Keratin 23 Kits (1) and many more products for this protein.
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Data show that Keratin23 (KRT23) knockdown affected molecules of the cell cycle and DNA replication, recombination and repair.
Increased expression of KRT23 is associated with colorectal cancer.
Data suggest a regulatory circuitry involving Smad4 dependent up-regulation of KRT23 (directly or indirectly) which in turn modulates the interaction between KRT23 and 14-3-3epsilon leading to a cytoplasmic sequestration of 14-3-3epsilon.
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.
, keratin complex 1, acidic, gene 23
, keratin, type I cytoskeletal 23
, type I intermediate filament cytokeratin
, cytokeratin 23
, histone deacetylase inducible keratin 23
, hyperacetylation-inducible type I keratin