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The protein encoded by KRT4 is a member of the keratin gene family. Additionally we are shipping Keratin 4 Antibodies (114) and Keratin 4 Kits (5) and many more products for this protein.
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The crystal structure of recombinant Srr-1-K4BD(485-642) and its possible mode of interaction with K4 through docking studies, are reported.
Identification of a mutation of the keratin 4 gene recurrent in a family affected by white sponge nevus.
The aberrant expression of K4 and K13 (show KCNG1 Proteins) and concomitant up-regulation of the other keratins may be one of the causative factors for morphological alterations in the affected epithelium.
Fascin (show FSCN1 Proteins) has a potential role as an early detection biomarker and CK4 as a tumor marker in esophageal squamous cell carcinoma.
Deletion of the srr-1 gene in the genome of S. agalactiae revealed that this gene plays a role in bacterial binding to human K4 and that it is involved in adherence to epithelial HEp-2 cells.
2 new mutations were found in the keratin 4 gene, the heterozygous missense mutation 1829G-->A in exon 2B, and 2324A-->G in non-coding region, which may be related with the development of WSN.
Failure to phosphorylate HsCyk-4 blocks Ect2 (show ECT2 Proteins) recruitment to the central spindle and the subsequent induction of furrowing.
Data found that Plk1 binds and directly phosphorylates the HsCYK-4 at the midzone and this modification creates a major docking site for the tandem BRCT repeats of the Rho GTP (show AK3 Proteins) exchange factor Ect2 (show ECT2 Proteins).
Infection by HPV stimulates the expression of cytokeratin 4
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
, keratin 8
, cytokeratin 4
, keratin, type II cytoskeletal 4
, type-II keratin Kb4
, type II keratin Kb4
, 57kDa keratin
, 57kd keratin
, cytoskeletal 57 kDa keratin
, keratin complex 2, basic, gene 4