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KRT78 is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Additionally we are shipping Keratin 78 Antibodies (16) and and many more products for this protein.
K78 is strongly expressed in the basal and parabasal cell layers with decreasing intensity in the lower suprabasal cells of keratinising and non-keratinising squamous epithelia and keratinocyte cultures.
This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.
, keratin 5b
, keratin, type II cytoskeletal 78
, type-II keratin Kb40