anti-Keratin 8 (KRT8) Antibodies

KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Additionally we are shipping Keratin 8 Proteins (40) and Keratin 8 Kits (19) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KRT8 3856 P05787
KRT8 16691 P11679
KRT8 25626 Q10758
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Keratin 8 Antibodies at antibodies-online.com

Showing 10 out of 805 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-KRT8 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Jurkat cell lysate Immunohistochemistry with Small intestine tissue at an antibody concentration of 5µg/ml using anti-KRT8 antibody (ARP42028_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-KRT8 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate Immunohistochemistry with Small intestine tissue at an antibody concentration of 5µg/ml using anti-KRT8 antibody (ARP42029_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Cytokeratin 8 staining in NIH3T3 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Cytokeratin 8 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Hamster Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   50 μg Log in to see 6 to 8 Days
$368.50
Details
Human Mouse Un-conjugated FACS, IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF (cc), IF (p), IHC (p), WB Formalin-fixed and rat colon tissue labeled with Anti-CK8 Polyclonal Antibody, Unconjugated (ABIN737751) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and mouse stomach tissue labeled with Anti-CK8 Polyclonal Antibody, Unconjugated (ABIN737751) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   1 mL Log in to see 6 to 8 Days
$308.00
Details
Human Mouse Un-conjugated IHC (fro), IHC (p), WB   1 mL Log in to see 6 to 8 Days
$456.50
Details
Cow Mouse Un-conjugated IHC (fro), IF, IHC (p), IP, WB   0.1 mg Log in to see 6 to 8 Days
$253.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from 293 cells, treated with EGF 200ng/ml 30', using Keratin 8 (Ab-431) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Keratin 8 (Ab-431) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details

KRT8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
, , ,
,
, , , , , , , , , , , , , , , , , , ,
Mouse (Murine) , , , ,
, , ,
,
, , , , , , , , , , , , , , , , , , ,
Rat (Rattus) , , , ,
, , ,
,
, , , , , , , , , , , , , , , , , , ,

Top referenced anti-Keratin 8 Antibodies

  1. Human Monoclonal KRT8 Primary Antibody for ICC, FACS - ABIN335327 : Ivanyi, Groeneveld, Van Doornewaard, Mooi, Hageman: Keratin subtypes in carcinomas of the uterine cervix: implications for histogenesis and differential diagnosis. in Cancer research 1990 (PubMed)
    Show all 10 Pubmed References

  2. Human Monoclonal KRT8 Primary Antibody for ICC, FACS - ABIN335211 : Ramaekers, van Niekerk, Poels, Schaafsma, Huijsmans, Robben, Schaart, Vooijs: Use of monoclonal antibodies to keratin 7 in the differential diagnosis of adenocarcinomas. in The American journal of pathology 1990 (PubMed)
    Show all 10 Pubmed References

  3. Human Monoclonal KRT8 Primary Antibody for ICC, IHC (fro) - ABIN920531 : Ljubimov, Bartek, Couchman, Kapuller, Veselov, Kovarik, Perevoshchikov, Krutovskikh: Distribution of individual components of basement membrane in human colon polyps and adenocarcinomas as revealed by monoclonal antibodies. in International journal of cancer. Journal international du cancer 1992 (PubMed)
    Show all 4 Pubmed References

  4. Hamster Monoclonal KRT8 Primary Antibody for IHC (fro), IHC (p) - ABIN920532 : Moll, Franke, Schiller, Geiger, Krepler: The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. in Cell 1983 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal KRT8 Primary Antibody for ICC, IHC (fro) - ABIN920530 : Troyanovsky, Guelstein, Tchipysheva, Krutovskikh, Bannikov: Patterns of expression of keratin 17 in human epithelia: dependency on cell position. in Journal of cell science 1990 (PubMed)
    Show all 4 Pubmed References

  6. Human Polyclonal KRT8 Primary Antibody for IF (cc), IF (p) - ABIN737751 : Zhang, Li, Fu, Li: Calcitonin is expressed in the submaxillary glands of rats. in Bosnian journal of basic medical sciences / Udruženje basi?nih mediciniskih znanosti = Association of Basic Medical Sciences 2014 (PubMed)
    Show all 3 Pubmed References

  7. Chicken Monoclonal KRT8 Primary Antibody for IHC (fro), IHC (p) - ABIN268153 : Rossdeutscher, Li, Luco, Fadhil, Ochietti, Camirand, Huang, Reinhardt, Muller, Kremer: Chemoprevention activity of 25-hydroxyvitamin D in the MMTV-PyMT mouse model of breast cancer. in Cancer prevention research (Philadelphia, Pa.) 2015 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal KRT8 Primary Antibody for IHC (fro), IHC (p) - ABIN284054 : Fernandez-Valdivia, Mukherjee, Ying, Li, Paquet, DeMayo, Lydon: The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse. in Developmental biology 2009 (PubMed)
    Show all 2 Pubmed References

  9. Human Monoclonal KRT8 Primary Antibody for IHC (fro), IHC (p) - ABIN284055 : Bardag-Gorce, Oliva, Li, French, French: SAMe prevents the induction of the immunoproteasome and preserves the 26S proteasome in the DDC-induced MDB mouse model. in Experimental and molecular pathology 2010 (PubMed)
    Show all 2 Pubmed References

  10. Human Monoclonal KRT8 Primary Antibody for IF, IHC - ABIN965965 : Walker, Harris, Holloway, McKenzie, Wells, Robinson, Morris: Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast. in Cancer genetics and cytogenetics 2007 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Keratin 8 Interaction Partners

Human Keratin 8 (KRT8) interaction partners

  1. Histopathological differences between Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU)-ablated tissue and radiofrequency (RF)-ablated tissue were demonstrated. CK-8 was more reliable for cell viability assessment than H&E when used directly after ablation

  2. Loss of activating transcription factor 3 (ATF3 (show ATF3 Antibodies)) in knockout mice promotes the emergence of keratins CK5 (show KRT5 Antibodies)+CK8+ epithelial cells.

  3. Data show that the filament elongation of both desmin (show DES Antibodies) and keratin K8/K18 (show KRT18 Antibodies) proceeds very similar to that of vimentin (show VIM Antibodies).

  4. New insights into interactions between the nucleotide-binding domain of CFTR (show CFTR Antibodies) and keratin 8.

  5. We present results of a multicentre study measuring UBC (show RPS27A Antibodies)((R)) Rapid Test(test that detects fragments of cytokeratins 8 and 18 in urine) in bladder cancer patients and healthy controls with focus on carcinoma in situ (CIS (show CISH Antibodies)) and high-grade bladder cancer.

  6. Data show that after siRNA transfection, TGF-beta1 (show TGFB1 Antibodies) protein level was decreased, and CK18 (show KRT18 Antibodies) proteins was decreased, while CK8 proteins was increased, and TERT (show TERT Antibodies) protein expression was slightly increased at 96 h.

  7. The interplay between Solo protein and keratin 8/keratin 18 filaments plays a crucial role in tensile force-induced RhoA activation and consequent actin cytoskeletal reinforcement in endothelial cells.

  8. K8/18 filaments provide resistance to apoptosis in granulosa cell tumor cells by impairing FAS (show FAS Antibodies) expression.

  9. These metastatic tumors revealed no detectable expression of CK8/18, E-cadherin (show CDH1 Antibodies), VCAM-1 (show VCAM1 Antibodies), and ICAM-1 (show ICAM1 Antibodies)

  10. Data show that loss of epithelial membrane protein 2 (EMP2) is involved in sphingosylphosphorylcholine (SPC (show UCN3 Antibodies))-induced phosphorylation of keratin 8 (K8) via ubiquitination of protein phosphatase 2 (PP2A (show PPP2R4 Antibodies)) through alpha4 phosphoprotein (show IGBP1 Antibodies) by caveolin-1 (cav-1 (show CAV1 Antibodies)).

Pig (Porcine) Keratin 8 (KRT8) interaction partners

  1. This study reveals clear genetic-statistical evidence for a link of KRT8, FAF1 (show FAF1 Antibodies) and PTH1R (show PTH1R Antibodies) with some of leg weakness related traits in pigs.

  2. Mechanical injury of vascular smooth muscle up-regulated keratin 8.

Cow (Bovine) Keratin 8 (KRT8) interaction partners

  1. Results did not support that K8/K18 (show KRT18 Antibodies) filaments influence the expression of Fas (show FAS Antibodies) on the surface of luteal cells.

Mouse (Murine) Keratin 8 (KRT8) interaction partners

  1. Mitochondria in K8 wild-type beta cells and MIN6 insulinoma cells overexpressing K8 and 18 are more stationary compared with mitochondria in keratin-deficient cells

  2. K8/K18 (show KRT18 Antibodies)-dependent PKCdelta (show PKCd Antibodies)- and ASMase (show SMPD1 Antibodies)-mediated modulation of lipid raft size can explain the more prominent FasR-mediated signaling resulting from K8/K18 (show KRT18 Antibodies) loss.

  3. DRA mRNA levels were decreased by three- to fourfold and DRA protein was almost entirely lost in K8-/- cecum and proximal and distal colon compared with K8+/+.

  4. Upregulation of IL-22 (show IL22 Antibodies) in combination with a complete loss of its negative regulator IL-22BP (show IL22RA2 Antibodies), and increased downstream STAT3 (show STAT3 Antibodies)-signaling in K8(-/-) and K8(-/-)Apc (show APC Antibodies)(Min/+) colonic epithelia confirmed that the IL-22 (show IL22 Antibodies) pathway, important in inflammation, proliferation and tissue regeneration

  5. Krt8 deletion (Krt8(-/-)) in a mouse model of cystic fibrosis (show S100A8 Antibodies) (F508del-Cftr (show CFTR Antibodies) mice) increased the levels of circulating markers of bone formation, corrected the expression of osteoblast phenotypic genes, promoted trabecular bone formation and improved bone mass and microarchitecture. Krt8 deletion corrected overactive NF-kappaB (show NFKB1 Antibodies) signaling & decreased Wnt (show WNT2 Antibodies)-beta-catenin (show CTNNB1 Antibodies) signaling induced by F508del-Cftr (show CFTR Antibodies) mutation in osteoblasts.

  6. Autoantibodies to several antigens were identified in 81% of K8-null male mice 8 mo or older. Similar autoantibodies were detected in aging K18 (show KRT18 Antibodies)-null male mice that had a related liver phenotype but normal colon compared with K8-null mice

  7. The regulation of the SCFA-MCT1 (show MCTS1 Antibodies)-HMGCS2 (show HMGCS2 Antibodies) axis is disrupted in K8(-/-) colonocytes, suggesting a role for keratins in colonocyte energy metabolism and homeostasis.

  8. In several liver stress models epiplakin and K8 genes displayed identical expression patterns and transgenic K8 overexpression resulted in elevated hepatic epiplakin levels.

  9. In human failing myocardium, where TNF-alpha (show TNF Antibodies) expression is upregulated, K8/K18 (show KRT18 Antibodies) were also ectopically expressed

  10. The findings demonstrate the near complete loss of K8/K18 (show KRT18 Antibodies) with concomitant high levels of vimentin (show VIM Antibodies) in CT26 (show DDX53 Antibodies) cells, a chemically-induced mouse colonic tumor.

Zebrafish Keratin 8 (KRT8) interaction partners

  1. Data identify Danio rerio keratins 8/18 as the true orthologs of the human keratin pair 8/18.

Keratin 8 (KRT8) Antigen Profile

Protein Summary

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with anti-Keratin 8 (KRT8) Antibodies

  • keratin 8 (krt8) antibody
  • keratin, type II cytoskeletal 8 pseudogene (LOC693415) antibody
  • keratin, type II cytoskeletal 8 (LOC697116) antibody
  • keratin 8 (KRT8) antibody
  • keratin 8 pseudogene (LOC743020) antibody
  • keratin 8 pseudogene (LOC100345306) antibody
  • keratin 8 (Krt8) antibody
  • keratin 8 S homeolog (krt8.S) antibody
  • AA960620 antibody
  • AL022697 antibody
  • AU019895 antibody
  • Card2 antibody
  • cb186 antibody
  • CK-8 antibody
  • CK8 antibody
  • CYK8 antibody
  • CYKER antibody
  • DKFZp468F2127 antibody
  • DreK8 antibody
  • EndoA antibody
  • K2C8 antibody
  • K8 antibody
  • KERATIN8 antibody
  • KO antibody
  • Krt-2.8 antibody
  • krt2-5 antibody
  • krt2-8 antibody
  • KRT8 antibody
  • MGC69490 antibody
  • sb:cb186 antibody
  • wu:fa20h05 antibody
  • wu:fa95h10 antibody
  • wu:fb96c06 antibody
  • zf-K8 antibody
  • zfk8 antibody

Protein level used designations for anti-Keratin 8 (KRT8) Antibodies

keratin 8 , keratin complex 2, basic, gene 5 , cytokeratin 8 , cytokeratin-8 , keratin, type II cytoskeletal 8 , type-II keratin Kb8 , CK-8 , K8 , KERA , cytokeratin-A , keratin-8 , cytokeratin endo A , keratin complex 2, basic, gene 8 , etID33550.23 , etID43142.23 , etID43142.8 , keratin, type 2, gene 8

GENE ID SPECIES
431676 Xenopus (Silurana) tropicalis
693415 Macaca mulatta
697116 Macaca mulatta
700449 Macaca mulatta
737628 Pan troglodytes
743020 Pan troglodytes
100174430 Pongo abelii
100345306 Oryctolagus cuniculus
3856 Homo sapiens
100152077 Sus scrofa
281269 Bos taurus
101110495 Ovis aries
100348891 Oryctolagus cuniculus
16691 Mus musculus
25626 Rattus norvegicus
797433 Danio rerio
380217 Xenopus laevis
426896 Gallus gallus
486513 Canis lupus familiaris
Selected quality suppliers for anti-Keratin 8 (KRT8) Antibodies
Did you look for something else?