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Killer Cell Immunoglobulin Like Receptor 2DS1 Proteins (KIR2DS1)

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Additionally we are shipping Killer Cell Immunoglobulin Like Receptor 2DS1 Antibodies (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KIR2DS1 3806 Q14954
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Top Killer Cell Immunoglobulin Like Receptor 2DS1 Proteins at antibodies-online.com

Showing 4 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 11 to 12 Days
$483.84
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Human Un-conjugated   5 μg Log in to see 6 to 8 Days
$168.30
Details

KIR2DS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Killer Cell Immunoglobulin Like Receptor 2DS1 (KIR2DS1) Interaction Partners

Human Killer Cell Immunoglobulin Like Receptor 2DS1 (KIR2DS1) interaction partners

  1. Recurrent Pregnancy Loss in Women with Killer Cell Immunoglobulin-Like Receptor KIR2DS1 is Associated with an Increased HLA-C2 Allelic Frequency

  2. functional interactions between KIR (show GEM Proteins) and HLA modify risks of BCC and SCC (show CYP11A1 Proteins) and that KIR (show GEM Proteins) encoded by the B genes provides selective pressure for altered p53 (show TP53 Proteins) in BCC tumors.

  3. The activating KIR (show GEM Proteins) gene KIR2DS1 has an important predictive potential for early onset of type 1 autoimmune hepatitis.

  4. Absence of HLA-C2 for donor KIR2DL1 (show KIR2DL1 Proteins) was associated with higher grade II to IV (HR, 1.4; P = .002) and III to IV acute GVHD (HR, 1.5; P = .01) compared with HLA-C2(+) patients.

  5. frequency of the maternal KIR2DS1 gene lower in the preeclampsia group than control group

  6. Array CGH showed a 95 Kb de novo duplication on chromosome 19q13.4 encompassing four killer cell immunoglobulin-like receptor (KIR) genes.

  7. Data show that KIR2DL5 receptor, KIR2DS1 protein, KIR2DS5 protein and KIR3DS1 receptors were all significantly associated with high viral load.

  8. the frequencies of HLA-Cw07 were statistically significantly higher in the patient group than those in the control group (P = 0.009). KIR2DS1(+) HLA(-) Cw(Lys (show LYZ Proteins)) was more common in subjects with SLE

  9. Moreover, the frequency of activating genotypes in the AS patient group was significantly higher than in the healthy control group (P < 0.05). KIR2DS1 and KIR3DS1

  10. Effect of KIR2DS1 was most significant in pregnancies where its ligand, HLA-C2, was paternally but not maternally inherited by a fetus (p = 0.005, odds ratio = 2.65).

Killer Cell Immunoglobulin Like Receptor 2DS1 (KIR2DS1) Protein Profile

Protein Summary

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Gene names and symbols associated with KIR2DS1

  • killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 (KIR2DS1)
  • killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 (KIR3DL3)
  • CD158a protein
  • CD158H protein
  • CD158Z protein
  • KIR3DL7 protein
  • KIR44 protein
  • KIRC1 protein
  • p50.1 protein

Protein level used designations for KIR2DS1

CD158 antigen-like family member H , KIR2DL1-KIR2DS1 , MHC class I NK cell receptor Eb6 ActI , killer cell immunoglobulin-like receptor 2DS1 , killer cell immunoglobulin-like receptor KIRDS1 , killer-cell immunoglobulin-like receptor , CD158 antigen-like family member Z , killer cell Ig-like receptor KIR3DL7 , killer cell immunoglobulin-like receptor 3DL3 , killer cell inhibitory receptor 1

GENE ID SPECIES
3806 Homo sapiens
115653 Homo sapiens
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