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Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Additionally we are shipping Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 Proteins (10) and many more products for this protein.
Showing 10 out of 97 products:
Human Monoclonal KIR2DL1 Primary Antibody for EIA, IP - ABIN121182
Shin, Shin, Kim, Choi, Park, Kim: Monoclonal antibodies with various reactivity to p58 killer inhibitory receptors. in Hybridoma 2000
Influence of Differently Licensed KIR2DL1-Positive Natural Killer Cells in Transplant Recipients with Acute Leukemia
Educated natural killer cells expressing KIR2DL1 display functional advantage for anti-HIV-1 antibody-dependent activation.
KIR2DL1*022 and 2DL1*026 evolved in the KhoeSan after their divergence from other modern human populations.
Data suggest regulatory interactions between major histocompatibility antigen HLA-C and killer cell Ig-like receptor (show KIR2DL5B Antibodies) (KIR (show GEM Antibodies)) might promote Graft-versus-Leukemia effects following transplantation.
Coengagement of inhibitory receptors, either KIR2DL1 or CD94 (show KLRD1 Antibodies)-NKG2A (show KLRC1 Antibodies), did not inhibit phosphorylation of Stat5 (show STAT5A Antibodies) but inhibited selectively phosphorylation of Akt (show AKT1 Antibodies) and S6 ribosomal protein (show RPS6 Antibodies).
genetic association studies in Chinese Han population: Data suggest that the frequency of KIR2DL1 gene is increased in women with pre-eclampsia when homozygous HLA-C2 allele appears in the fetus.
Array CGH showed a 95 Kb de novo duplication on chromosome 19q13.4 encompassing four killer cell immunoglobulin-like receptor (show KIR2DS1 Antibodies) (KIR (show GEM Antibodies)) genes.
These results revealed that ITIM phosphorylation is controlled by self-association of KIR (show GEM Antibodies) and that His-36 serves as a gatekeeper to prevent unregulated signaling through KIR2DL1.
C2 of KIR2DL1 is a novel risk factor, and homozygosity for C1 is a protective factor for childhood B-ALL
We investigated the association of HLA alleles and KIR (show GEM Antibodies) ligands according to oligoclonal band status in multiple sclerosis patients.
The first and possibly only KIR (show GEM Antibodies) gene, named KIR2DL1, in Sus scrofa was identified.
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response.
CD158 antigen-like family member A
, MHC class I NK cell receptor
, killer Ig receptor
, killer cell immunoglobulin-like receptor 2DL1
, killer inhibitory receptor 2-2-1
, natural killer-associated transcript 1
, p58 NK cell inhibitory receptor NKR-K6
, p58 NK receptor CL-42/47.11
, p58 killer cell inhibitory receptor KIR-K64
, p58 natural killer cell receptor clones CL-42/47.11
, p58.1 MHC class-I-specific NK receptor
, killer cell immunoglobulin-like receptor 2DL5A
, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5