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Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2) ELISA Kits

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Additionally we are shipping KIR2DL2 Antibodies (30) and KIR2DL2 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human KIR2DL2 KIR2DL2 3803 P43627
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More ELISA Kits for KIR2DL2 Interaction Partners

Human Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2) interaction partners

  1. genetic association study in population in Eastern India: Data suggest that interactions between KIRs (KIR2DL2, KIR2DS4, KIR2DL3) and HLA ligands (HLAC1, HLAC2) contribute significantly toward susceptibility and protection toward type 1 diabetes.

  2. Allelic polymorphism of KIR2DL2/2DL3 in a southern Chinese population.

  3. a significant increase in the frequency of KIR2DL2 (P = 0.019) as well as KIR2DS2 (show KIR2DS2 ELISA Kits) (P = 0.008) in patients with neuroblastoma (show ARHGEF16 ELISA Kits) compared with the healthy control group, was found.

  4. Single Nucleotide Polymorphism in KIR2DL2 gene is associated with Asthma and Atopic Dermatitis.

  5. KIR2DL2 and KIR2DS2 genotype is associated with protection against primary biliary cirrhosis in Han population.

  6. Genetic risk for co-occurrence of type 1 diabetes and celiac disease is modified by HLA-C and killer immunoglobulin-like receptors.

  7. Authors showed an increase in HLA-C1/KIR2DL2 and HLA-C1/KIR2DL3 pairs in human papillomavirus high-risk infected patients (OR 3.05, 3.24) with invasive cervical cancer (OR 1.33, 3.68).

  8. KIR2DL3-positive NK cells were more sensitive to changes in the peptide content of MHC class I than KIR2DL2-positive NK cells.

  9. Authors showed a significant increased correlation between KIR2DL2/DS2, type 2 diabetes and HLA-C1C1 genotype in the type 2 diabetes patients infected with human herpesvirus 8.

  10. these results suggest that inhibitory KIR2DL2 and KIR2DL3, which are alleles of the same locus, play a role in the inverse effects on PM and PM/HIV co-infection

KIR2DL2 Antigen Profile

Antigen Summary

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Gene names and symbols associated with KIR2DL2

  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 (KIR2DL2) antibody
  • CD158b antibody
  • CD158B1 antibody
  • NKAT6 antibody
  • p58.2 antibody

Protein level used designations for KIR2DL2

CD158 antigen-like family member B1 , MHC class I NK cell receptor , NKAT-6 , killer cell immunoglobulin-like receptor 2DL2 , natural killer-associated transcript 6 , p58 NK receptor CL-43 , p58 natural killer cell receptor clone CL-43

GENE ID SPECIES
3803 Homo sapiens
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