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Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Additionally we are shipping KIR2DL3 Antibodies (147) and KIR2DL3 Kits (1) and many more products for this protein.
Showing 9 out of 13 products:
CD16+ cells were significantly more frequent among Natural Killer (NK) cells negative for the inhibitory KIR (iKIR) KIR2DL1, KIR2DL3, and KIR3DL1 than those positive for any one of these iKIR to the exclusion of the others, making iKIR+ NK cells poorer antibody dependent cellular cytotoxicity effectors than iKIR- NK cells.
These results show that 2DL3(+) NK cells are mediators of HIV-specific responses. Furthermore, responses of NK cell populations to iCD4 are influenced not only by NK cell education through specific KIR/HLA pairs, but also by differential HIV-mediated changes in HLA expression.
Results identified three SNPs (S320F, H245Y, and H77Y) as highly deleterious in KIR2DL3 and nine SNPs (R157Q, H156Y, S63L, R157 W, F179 V, H128R, T101 M, R180C and F176I) in case of IFNL3 (show IL28B Proteins), in coding region only with high conservation ranks highlighting the functional SNPs on phenotypic variability and disease susceptibility on HCV clearance candidate genes.
KIR2DL2/KIR2DL3-glutamate(35) alleles are functionally stronger than -glutamine(35) alleles.
KIR2DL2 (show KIR2DL2 Proteins)/2DS2-C1C1 genotype is associated with type 1 diabetes in Saudi children
study compared KIR gene repertoire of HIV-1 positive with exposed uninfected (EU)) infants to elucidate its association with transmission; results revealed presence of significantly high frequencies of activating gene KIR 2DS5 and inhibitory gene KIR 2DL3 in EU infants as compared to HIV-1 positive infants
genetic association study in population in Eastern India: Data suggest that interactions between KIRs (KIR2DL2 (show KIR2DL2 Proteins), KIR2DS4 (show KIR2DS4 Proteins), KIR2DL3) and HLA ligands (HLAC1, HLAC2) contribute significantly toward susceptibility and protection toward type 1 diabetes.
Allelic polymorphism of KIR2DL2 (show KIR2DL2 Proteins)/2DL3 in a southern Chinese population.
The authors have identified a deleterious effect of the KIR2DL3-HLA-C1 receptor-ligand combination on HIV clinical outcomes in a Thai cohort.
Single Nucleotide Polymorphism in KIR2DL3 gene is associated with Asthma and Atopic Dermatitis.
Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.
CD158 antigen-like family member B2
, MHC class I NK cell receptor
, killer cell immunoglobulin-like receptor 2DL3
, killer inhibitory receptor cl 2-3
, natural killer associated transcript 2
, natural killer cell inhibitory receptor KIR2DL3
, natural killer-associated transcript 2
, p58 NK receptor CL-6
, p58 natural killer cell receptor clone CL-6
, p58.2 MHC class-I specific NK receptor
, p58.2 MHC class-I-specific NK receptor