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Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5B Proteins (KIR2DL5B)

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Additionally we are shipping Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5B Antibodies (26) and many more products for this protein.

list all proteins Gene Name GeneID
KIR2DL5B 553128
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Top Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5B Proteins at antibodies-online.com

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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
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Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
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KIR2DL5B Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5B (KIR2DL5B) Interaction Partners

Human Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5B (KIR2DL5B) interaction partners

  1. We found the presence of KIR2DL5B to be associated with inferior transformation-free survival and event-free survival in patients with chronic phase-chronic myeloid leukemia (show BCL11A Proteins)

  2. Data show that KIR2DL5 receptor, KIR2DS1 protein, KIR2DS5 protein and KIR3DS1 receptors were all significantly associated with high viral load.

  3. The genes KIR2DL5, KIR2DS3 and KIR2DS5 were present in a significantly higher proportion of individuals in the asymptomatic control group than in the malaria cases.

  4. indicate that killer-cell immunoglobulin-like receptors (KIRs)activator (KIR3DS1 and KIR2DS5) and inhibitory (KIR2DL5) genes are associated with severe pandemic influenza A (H1N1) 2009 infections.

  5. KIR2DL3, KIR2DS5 and KIR2DL5B genes may be correlated with pathogenesis of nasopharyngeal carcinoma in the Chinese southern Han population.

  6. KIR2DL5 is a candidate gene involved in immunomodulation associated with non-response to antiviral therapy.

  7. Human KIR2DL5 has at least 4 gene variants, whose exons differ by 2 to 8 nucleotides. These structurally similar variants are encoded by alleles of 2 different loci, KIR2DL5A and KIR2DL5B, which map to different regions of the KIR-gene cluster.

  8. The frequencies of KIR2DS1 (show KIR2DS1 Proteins) and KIR2DL5 were significantly increased in psoriasis vulgaris cases compared with controls

  9. We report here the identification and characterization of the receptor encoded by KIR2DL5 using a newly generated specific mAb that recognizes its most commonly expressed allele, KIR2DL5A*001.

  10. Sequencing a KIR2DL5 variant using a first-generation high-throughput method proves it is a newly discovered allele, one that appears associated with Hispanic and Native American populations.

Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5B (KIR2DL5B) Protein Profile

Protein Summary

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Gene names and symbols associated with KIR2DL5B

  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B (KIR2DL5B)
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A (KIR2DL5A)
  • CD158F protein
  • KIR2DL5 protein
  • KIR2DL5.1 protein
  • KIR2DL5.2 protein
  • KIR2DL5.3 protein
  • KIR2DL5B protein
  • KIR2DLX protein

Protein level used designations for KIR2DL5B

CD158 antigen-like family member F2 , killer cell Ig-like receptor , killer cell immunoglobulin-like receptor 2DL5B , killer cell immunoglobulin-like receptor 2DLX , killer cell immunoglobulin-like receptor 2DL5A , killer cell immunoglobulin-like receptor KIR2DL5A , killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5 , killer-cell Ig-like receptor

GENE ID SPECIES
553128 Homo sapiens
57292 Homo sapiens
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