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Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Additionally we are shipping and Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 Kits (5) and many more products for this protein.
Showing 10 out of 124 products:
Human Monoclonal KIR3DL1 Primary Antibody for ELISA, WB - ABIN2656954
Gumperz, Valiante, Parham, Lanier, Tyan et al.: Heterogeneous phenotypes of expression of the NKB1 natural killer cell class I receptor among individuals of different human histocompatibility leukocyte antigens types appear genetically regulated, ... in The Journal of experimental medicine 1996
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Human Monoclonal KIR3DL1 Primary Antibody for FACS, IP - ABIN2661523
Uhrberg, Valiante, Shum, Shilling, Lienert-Weidenbach, Corliss, Tyan, Lanier, Parham: Human diversity in killer cell inhibitory receptor genes. in Immunity 1998
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Human Monoclonal KIR3DL1 Primary Antibody for FACS - ABIN2658031
Wagtmann, Rajagopalan, Winter, Peruzzi, Long: Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer. in Immunity 1996
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Human Monoclonal KIR3DL1 Primary Antibody for FACS - ABIN2660956
DAndrea, Chang, Franz-Bacon, McClanahan, Phillips, Lanier: Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes. in Journal of immunology (Baltimore, Md. : 1950) 1995
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Human Monoclonal KIR3DL1 Primary Antibody for FACS - ABIN2659980
Colonna, Samaridis: Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. in Science (New York, N.Y.) 1995
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Human Monoclonal KIR3DL1 Primary Antibody for FACS - ABIN2663068
Litwin, Gumperz, Parham, Phillips, Lanier: NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules. in The Journal of experimental medicine 1994
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Human Polyclonal KIR3DL1 Primary Antibody for IHC (fro), WB - ABIN441607
Murakawa, Iwata, Takeshita, Ozawa: Immunoelectron microscopic observation of the subcellular localization of kisspeptin, neurokinin B and dynorphin A in KNDy neurons in the arcuate nucleus of the female rat. in Neuroscience letters 2016
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Authors results suggest that low cell-surface expression of KIR3DL1 in the presence of the HLA-Bw4 epitope is associated with an increased risk for developing psoriasis.
Using depletion studies and Killer immunoglobulin-like receptors-transfected cell lines, demonstrated that the dengue virus NS1 (show PTPN11 Antibodies) tetramer bound the inhibitory receptor KIR3DL1.
KIR3DL1 interaction with HLA-B27 is altered by ankylosing spondylitis associated ERAP1 and enhanced by MHC class I cross-linking
In early axial spondyloarthritis and ankylosing spondylitis Dutch patients, no copy number changes were found for KIR3DL1.
KIR3DL1 has a protective effect against the more severe manifestations of ankylosing spondylitis.
Study shows KIR3DL1 and KIR2DS4 (show KIR2DS4 Antibodies) gene variants are linked and that the gene KIR2DS5 is only present in the telomeric half of the KIR (show GEM Antibodies) locus. Study revealed novel insights in the highly organized distribution of KIR (show GEM Antibodies) genes.
Individuals who carried both KIR3DS1 and Bw4*80I did not remain HIV seronegative longer than those from a control group who were homozygous for HLA-Bw6 and carried no HLA-A locus Bw4 alleles
Protective genotypes in HIV infection reflect superior function of KIR3DS1 over KIR3DL1-expressing CD8 (show CD8A Antibodies)+ T cells.
KIR3DL1-HLA-Bw4 combination and IL28B (show IL28B Antibodies) polymorphism predict response to Peg (show PAEP Antibodies)-IFN and ribavirin with and without telaprevir in chronic hepatitis C patients.
the strict conformation of HLA-Bw4 allotypes, held in place by the Glu (show DCTN1 Antibodies)(76)-Arg(83) interaction, facilitates KIR3DL1 binding, whereas Bw6 allotypes present a platform on the alpha1 helix that is less permissive for KIR3DL1 binding.
studies indicate that KIR3DL1 expression may negatively regulate Treg function and suggest a previously undescribed target for improving immune tolerance for potential treatment of autoimmune diseases like IDDM
first close rodent homologue of the NK receptor KIR family; shares 40% amino acid identity with primate KIR (show GEM Antibodies) family members
Selective expression of killer cell immunoglobulin-like receptor (show KIR2DS1 Antibodies) (KIR (show GEM Antibodies)) genes in subregions of the mouse brain where synaptic plasticity and neurogenesis occur, including olfactory bulbs, rostral migratory stream and dentate gyrus of hippocampus.
cloned Kir (show GEM Antibodies) cDNAs from multiple strains of mice. Sequencing of the cDNA clones showed that the Kir3dl1 gene is found in C3H/HeJ and CBA/J but not in B6 mice.
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
, killer immunoglobulin-like receptor KIR3DL-like 1
, killer cell immunoglobulin-like receptor variant 001
, killer cell immunoglobulin-like receptor KIR3DL1-like 1
, killer cell immunoglobulin-like receptor 3DL1-like
, CD158 antigen-like family member E
, HLA-BW4-specific inhibitory NK cell receptor
, KIR antigen 3DL1
, MHC class I NK cell receptor
, killer Ig receptor
, killer cell immunoglobulin-like receptor 3DL1
, natural killer-associated transcript 3
, p70 NK receptor CL-2/CL-11
, p70 killer cell inhibitory receptor
, p70 natural killer cell receptor clones CL-2/CL-11
, KIR-like receptor 1
, killer cell immunoglobulin-like receptor Kir3dl1
, killer immunoglobulin receptor-like protein 1