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Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2) ELISA Kits

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Additionally we are shipping KIR2DS2 Antibodies (32) and KIR2DS2 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human KIR2DS2 KIR2DS2 100132285 P43631
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More ELISA Kits for KIR2DS2 Interaction Partners

Human Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2) interaction partners

  1. this study was to look for immunogenetic determinants in the pathogenesis of FMF (show MEFV ELISA Kits) and find out if KIR (show GEM ELISA Kits) are related to susceptibility. An activator KIR (show GEM ELISA Kits) gene, KIR2DS2, was significantly more frequent in FMF (show MEFV ELISA Kits) patients (p=0.036).

  2. a significant increase in the frequency of KIR2DL2 (show KIR2DL2 ELISA Kits) (P = 0.019) as well as KIR2DS2 (P = 0.008) in patients with neuroblastoma (show ARHGEF16 ELISA Kits) compared with the healthy control group, was found.

  3. Single Nucleotide Polymorphism in KIR2DS2 gene is associated with Asthma and Atopic Dermatitis.

  4. KIR2DL2 and KIR2DS2 genotype is associated with protection against primary biliary cirrhosis in Han population.

  5. CD4(+) CD28(-) cells exhibited increased KIR2DS2, reduced KIR2DL3 and increased DAP12 expression in HD-ESRD compared with NDD-CKD patients.

  6. Authors showed a significant increased correlation between KIR2DL2/DS2, type 2 diabetes and HLA-C1C1 genotype in the type 2 diabetes patients infected with human herpesvirus 8.

  7. NK cells with KIR2DS2 immunogenotype have a functional activation advantage to efficiently kill glioblastoma and prolong animal survival.

  8. There is an association of the KIR2DS gene, especially KIR2DS2, with psoriatic arthritis.

  9. Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11.

  10. Analysis of this large cohort from Uganda in the context of other African populations reveals variations in KIR (show GEM ELISA Kits) and HLA-C1 and C2 that are consistent with migrations within Africa and potential selection pressures on these genes.

KIR2DS2 Antigen Profile

Antigen Summary

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Gene names and symbols associated with KIR2DS2

  • killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 (KIR2DS2) antibody
  • 183ActI antibody
  • CD158b antibody
  • CD158J antibody
  • cl-49 antibody
  • NKAT5 antibody

Protein level used designations for KIR2DS2

1060P11.9.2 , CD158 antigen-like family member J , MHC class I NK cell receptor , NK receptor 183 ActI , NKAT-5 , killer cell immunoglobulin-like receptor 2DS2 , killer-cell Ig-like receptor , killer-cell immunoglobulin-like receptor two domains short tail 2 protein , natural killer associated transcript 5 , natural killer cell inhibitory receptor , natural killer-associated transcript 5 , p58 KIR , p58 NK receptor CL-49 , p58 killer cell inhibitory receptor KIR-K7a , p58 natural killer cell receptor clone CL-49

GENE ID SPECIES
100132285 Homo sapiens
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