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Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. Additionally we are shipping and Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 1 Kits (6) and many more products for this protein.
Showing 10 out of 135 products:
Human Monoclonal KIR3DL1 Primary Antibody for FACS - ABIN2658031
Gumperz, Valiante, Parham, Lanier, Tyan et al.: Heterogeneous phenotypes of expression of the NKB1 natural killer cell class I receptor among individuals of different human histocompatibility leukocyte antigens types appear genetically regulated, ... in The Journal of experimental medicine 1996
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Human Monoclonal KIR3DL1 Primary Antibody for FACS - ABIN2660956
Uhrberg, Valiante, Shum, Shilling, Lienert-Weidenbach, Corliss, Tyan, Lanier, Parham: Human diversity in killer cell inhibitory receptor genes. in Immunity 1998
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Human Monoclonal KIR3DL1 Primary Antibody for FACS - ABIN4898695
Béziat, Dalgard, Asselah, Halfon, Bedossa, Boudifa, Hervier, Theodorou, Martinot, Debré, Björkström, Malmberg, Marcellin, Vieillard: CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients. in European journal of immunology 2012
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Human Polyclonal KIR3DL1 Primary Antibody for IHC (fro), WB - ABIN441607
Murakawa, Iwata, Takeshita, Ozawa: Immunoelectron microscopic observation of the subcellular localization of kisspeptin, neurokinin B and dynorphin A in KNDy neurons in the arcuate nucleus of the female rat. in Neuroscience letters 2016
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Human Monoclonal KIR3DL1 Primary Antibody for FACS - ABIN4898699
Taner, Pando, Roberts, Schellekens, Marsh, Malmberg, Parham, Brodsky: Interactions of NK cell receptor KIR3DL1*004 with chaperones and conformation-specific antibody reveal a functional folded state as well as predominant intracellular retention. in Journal of immunology (Baltimore, Md. : 1950) 2010
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Human Monoclonal KIR3DL1 Primary Antibody for FACS - ABIN4900806
Denman, Senyukov, Somanchi, Phatarpekar, Kopp, Johnson, Singh, Hurton, Maiti, Huls, Champlin, Cooper, Lee: Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells. in PLoS ONE 2012
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CD16 (show CD16 Antibodies)+ cells were significantly more frequent among Natural Killer (NK) cells negative for the inhibitory KIR (show GEM Antibodies) (iKIR) KIR2DL1 (show KIR2DL1 Antibodies), KIR2DL3 (show KIR2DL3 Antibodies), and KIR3DL1 than those positive for any one of these iKIR to the exclusion of the others, making iKIR+ NK cells poorer antibody dependent cellular cytotoxicity effectors than iKIR- NK cells.
evidence that KIR (show GEM Antibodies)-regulated signaling contributes to Behcet's disease
KIR3DL1 in combination with HLA-A and -B alleles bearing the Bw4 motif show strong protective effect against multiple sclerosis in African Americans.
Authors results suggest that low cell-surface expression of KIR3DL1 in the presence of the HLA-Bw4 epitope is associated with an increased risk for developing psoriasis.
Using depletion studies and Killer immunoglobulin-like receptors-transfected cell lines, demonstrated that the dengue virus NS1 (show PTPN11 Antibodies) tetramer bound the inhibitory receptor KIR3DL1.
KIR3DL1 interaction with HLA-B27 is altered by ankylosing spondylitis associated ERAP1 and enhanced by MHC class I cross-linking
In early axial spondyloarthritis and ankylosing spondylitis Dutch patients, no copy number changes were found for KIR3DL1.
KIR3DL1 has a protective effect against the more severe manifestations of ankylosing spondylitis.
Study shows KIR3DL1 and KIR2DS4 (show KIR2DS4 Antibodies) gene variants are linked and that the gene KIR2DS5 is only present in the telomeric half of the KIR (show GEM Antibodies) locus. Study revealed novel insights in the highly organized distribution of KIR (show GEM Antibodies) genes.
Individuals who carried both KIR3DS1 and Bw4*80I did not remain HIV seronegative longer than those from a control group who were homozygous for HLA-Bw6 and carried no HLA-A locus Bw4 alleles
studies indicate that KIR3DL1 expression may negatively regulate Treg function and suggest a previously undescribed target for improving immune tolerance for potential treatment of autoimmune diseases like IDDM
first close rodent homologue of the NK receptor KIR family; shares 40% amino acid identity with primate KIR (show GEM Antibodies) family members
Selective expression of killer cell immunoglobulin-like receptor (show KIR2DS1 Antibodies) (KIR (show GEM Antibodies)) genes in subregions of the mouse brain where synaptic plasticity and neurogenesis occur, including olfactory bulbs, rostral migratory stream and dentate gyrus of hippocampus.
cloned Kir (show GEM Antibodies) cDNAs from multiple strains of mice. Sequencing of the cDNA clones showed that the Kir3dl1 gene is found in C3H/HeJ and CBA/J but not in B6 mice.
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
, killer immunoglobulin-like receptor KIR3DL-like 1
, killer cell immunoglobulin-like receptor variant 001
, killer cell immunoglobulin-like receptor KIR3DL1-like 1
, killer cell immunoglobulin-like receptor 3DL1-like
, CD158 antigen-like family member E
, HLA-BW4-specific inhibitory NK cell receptor
, KIR antigen 3DL1
, MHC class I NK cell receptor
, killer Ig receptor
, killer cell immunoglobulin-like receptor 3DL1
, natural killer-associated transcript 3
, p70 NK receptor CL-2/CL-11
, p70 killer cell inhibitory receptor
, p70 natural killer cell receptor clones CL-2/CL-11
, KIR-like receptor 1
, killer cell immunoglobulin-like receptor Kir3dl1
, killer immunoglobulin receptor-like protein 1