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Receptor on natural killer (NK) cells for class I MHC.. Additionally we are shipping and many more products for this protein.
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Ly49H has a role in antiviral activity.
Signaling through the Ly49H receptor is necessary to induce transient Ly49H-mediated natural killer (NK) cell tolerance during chronic viral infection.
m157 gene(G1F)-Ly49C (show Klra3 Antibodies) interactions cause no apparent attenuating effect on clearance of murine cytomegalovirus from natural killer (NK) cells.
In mouse cytomegalovirus(MCMV)-resistant mice, the viral m157 protein engages a related activating receptor (Ly49H) and confers host protection
Genetic control of innate immune responses against cytomegalovirus can be attributed to a single genetic locus termed Cmv1.
Natural killer cells in New Zealand White mice apparently use a Cmv1-independent mechanism controlled through multiple genes to limit murine cytomegalovirus infection.
m157 mutations are predicted to alter the conformation of a putative m157 interface with Ly49H, one that relies on the position of a critical alpha0 helix of m157
transgenic mice were more susceptible to MCMV infection and were unable to reject m157-Tg bone marrow, suggesting defects in Ly49H(+) NK cells
Ly49h is necessary for genetic resistance to murine cytomegalovirus.
Ly49H-positive natural killer (NK) cells contain a systemic production of cytokines that may contribute to murine cytomegalovirus-induced pathology and play a central role in maintaining normal spleen cell microarchitecture.
Receptor on natural killer (NK) cells for class I MHC.
T-cell surface glycoprotein Ly-49H
, cytomegalovirus resistance 1
, killer cell lectin-like receptor 8
, lymphocyte antigen 49h