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Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) ELISA Kits

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. Additionally we are shipping Killer Cell Lectin-Like Receptor Subfamily C, Member 1 Antibodies (98) and Killer Cell Lectin-Like Receptor Subfamily C, Member 1 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat KLRC1 KLRC1 29683  
Anti-Human KLRC1 KLRC1 3821 P26715
Anti-Mouse KLRC1 KLRC1 16641  
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More ELISA Kits for Killer Cell Lectin-Like Receptor Subfamily C, Member 1 Interaction Partners

Human Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) interaction partners

  1. CD94 (show KLRD1 ELISA Kits) and NKG2A polymorphisms may contribute to genetic susceptibility to rheumatoid arthritis or affect the response to anti-TNF (show TNF ELISA Kits) therapy in patients of Caucasian origin.

  2. NK cell maturation to CD56(dim) subset associated with high levels of NCRs overrides the inhibitory effect of NKG2A and recovers impaired NK cell cytolytic potential after allogeneic hematopoietic stem cell transplantation.

  3. Coengagement of inhibitory receptors, either KIR2DL1 (show KIR2DL1 ELISA Kits) or CD94 (show KLRD1 ELISA Kits)-NKG2A, did not inhibit phosphorylation of Stat5 (show STAT5A ELISA Kits) but inhibited selectively phosphorylation of Akt (show AKT1 ELISA Kits) and S6 ribosomal protein (show RPS6 ELISA Kits).

  4. The presence of TIM3 (show HAVCR2 ELISA Kits)+and/or NKG2A+ T cells is associated with the absence of recurrences and a longer recurrence-free survival.

  5. Balance between activating NKG2D (show KLRK1 ELISA Kits), DNAM-1 (show CD226 ELISA Kits), NKp44 and NKp46 (show NCR1 ELISA Kits) and inhibitory CD94 (show KLRD1 ELISA Kits)/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.

  6. Results suggested that the low expression level of CD94 (show KLRD1 ELISA Kits)/NKG2A upon gammadelta T cell activation might lead to the over-activation of gammadelta T cells in patients with SLE.

  7. The positive expression rate of NKG2D (show KLRK1 ELISA Kits) and NKG2A on NK cells and CD3 (show CD3 ELISA Kits)(+) T cells in ALL patients was no significantly different from that in AML (show RUNX1 ELISA Kits) patients.

  8. The level of NKG2A expression on resting CD8 (show CD8A ELISA Kits)-positive T cells inversely correlated with acquisition of regulatory function when activated.

  9. These results suggested that these glycans can interact with NKG2D (show KLRK1 ELISA Kits) and CD94 (show KLRD1 ELISA Kits) to modulate NK cell-dependent cytotoxicity.

  10. The differences of CD94 (show KLRD1 ELISA Kits) and NKG2 expression between nasal NK/T-cell lymphomas and B cell lymphoma or T cell lymphoma were statistically significant.

Mouse (Murine) Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) interaction partners

  1. NKG2A optimizes CD8 (show CD8A ELISA Kits)(+) T cell responses during an acute poxvirus infection.

  2. Results demonstrate the immunoregulatory role of CD8 (show CD8A ELISA Kits)(+) NKG2A expression in virus infection, which negatively regulates T cell effector functions and contributes to protection of tissue integrity during virus clearance.

  3. role in NK cell-mediated protection from DSS (show PMP22 ELISA Kits)-induced colitis

  4. Endogenous NKG2A contributes to the rejection of cells lacking human HLA-Cw3.

  5. The complex interplay between various stimuli may account for the variable expression of CD94 (show KLRD1 ELISA Kits)/NKG2A during responses to different pathogens in vivo.

  6. expression of CD94 (show KLRD1 ELISA Kits) and its associated NKG2A, NKG2C (show KLRC2 ELISA Kits), and NKG2E (show KLRC3 ELISA Kits) subunits is dispensable for NK cell development, education, and many NK cell functions

  7. The NKG2A+KLRG1 (show KLRG1 ELISA Kits)+ positive phenotype correlates with protective efficacy during antigenic recall from a pool of CD8 (show CD8A ELISA Kits) T cells during persistent gamma-herpesvirus 68 infection.

  8. Data suggest that the liver environment regulates NK cell receptor expression and that IL-10 contributes to the regulation of liver NK cells, in part, by maintaining a greater percentage of the hyporesponsive NKG2A(+)Ly49(-) NK cells in the liver.

  9. Implications of CD94 (show KLRD1 ELISA Kits) deficiency and monoallelic NKG2A expression for natural killer cell development and repertoire formation.

  10. the CD94 (show KLRD1 ELISA Kits)/NKG2A inhibitory receptor plays a critical role in down-regulating invariant NK-cell responses

Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1) Antigen Profile

Antigen Summary

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

Gene names and symbols associated with KLRC1

  • killer cell lectin-like receptor subfamily C, member 1 (Klrc1) antibody
  • killer cell lectin-like receptor subfamily C, member 1 (KLRC1) antibody
  • killer cell lectin-like receptor subfamily C, member 3 (KLRC3) antibody
  • CD159a antibody
  • KLRC1 antibody
  • NKG2 antibody
  • NKG2-A antibody
  • NKG2A antibody
  • NKG2B antibody
  • rNKG2A antibody

Protein level used designations for KLRC1

natural killer cell protein group 2-A (NKG2A) , CD159 antigen-like family member A , NK cell receptor A , NKG2-A/B-activating NK receptor , NKG2-A/NKG2-B type II integral membrane protein , killer cell lectin-like receptor subfamily C, member 1 , C-lectin type II protein , NKG2-1/B activating NK receptor , NKG2-A/B type II integral membrane protein , natural killer cell lectin , natural killer group protein 2

GENE ID SPECIES
29683 Rattus norvegicus
450131 Pan troglodytes
514897 Bos taurus
611325 Canis lupus familiaris
100126720 Papio anubis
100144622 Sus scrofa
3821 Homo sapiens
16641 Mus musculus
574146 Macaca mulatta
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