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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. Additionally we are shipping Killer Cell Lectin-Like Receptor Subfamily C, Member 2 Antibodies (40) and Killer Cell Lectin-Like Receptor Subfamily C, Member 2 Proteins (10) and many more products for this protein.
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Assessment of NK cell repertoires in 60 NKG2C(-/-) donors revealed a broad range of NK cell populations displaying characteristic footprints of adaptive NK cells, including a terminally differentiated phenotype, functional reprogramming, and epigenetic remodeling of the interferon (IFN)-gamma (show IFNA ELISA Kits) promoter.
HLA-E (show HLAE ELISA Kits) regulates NKG2C+ natural killer cell function through presentation of a restricted peptide repertoire
Data suggest the proinflammatory potential of NKG2C(bright) NK cells.
lack of expression of NKG2C may be associated with altered control of human cytomegalovirus infection in childhood
No difference in the prevalence of NKG2C deletion was observed.
NKG2C receptor deletion and a functional polymorphism in its ligand HLA-E may play a role in psoriasis susceptibility
NKG2C(hi)CD57 (show B3GAT1 ELISA Kits)+ NK cells respond specifically to acute infection with cytomegalovirus and not Epstein-Barr virus.
NKG2C zygosity influences CD94 (show KLRD1 ELISA Kits)/NKG2C receptor function and the NK-cell compartment redistribution in response to human cytomegalovirus.
coexpression of killer cell Ig-like receptor (KIR (show GEM ELISA Kits)) and NKG2C on expanded NK cell subsets could be related to a functional contribution of KIR (show GEM ELISA Kits) in cytomegalovirus infection
The increased expression of NKG2C in HIV patients indicate that NKG2C is important in the defense against HIV infection and progression.
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined.
CD159 antigen-like family member C
, NK cell receptor C
, NKG2-C type II integral membrane protein
, NKG2-C-activating NK receptor