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Killer Cell Lectin-Like Receptor Subfamily F, Member 1 Proteins (KLRF1)

KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009].. Additionally we are shipping Killer Cell Lectin-Like Receptor Subfamily F, Member 1 Antibodies (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KLRF1 51348 Q9NZS2
KLRF1    
KLRF1    
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Top Killer Cell Lectin-Like Receptor Subfamily F, Member 1 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Cynomolgus Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,398.00
Details

KLRF1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Cynomolgus

Macaca fascicularis

Top referenced Killer Cell Lectin-Like Receptor Subfamily F, Member 1 Proteins

  1. Cynomolgus KLRF1 Protein expressed in Human Cells - ABIN2009940 : Kuttruff, Koch, Kelp, Pawelec, Rammensee, Steinle: NKp80 defines and stimulates a reactive subset of CD8 T cells. in Blood 2009 (PubMed)

More Proteins for Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1) Interaction Partners

Human Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1) interaction partners

  1. IL-15 (show IL15 Proteins)+IL-12 (show IL12A Proteins) has an immunomodulatory effect on NK cell subsets from HIV-infected individuals viz down-regulation of iNKRs, elevation of activatory receptors NKp46 (show NCR1 Proteins) and NKG2D (show KLRK1 Proteins), and induction of coreceptor NKp80.

  2. our data report a previously unrecognized regulatory circuit enabling autonomous control of human NK cell responses via the NKp80-AICL (show CLEC2B Proteins) axis.

  3. Two non-consensus amino acids of NKp80, in particular arginine 6, critically impair both hemi-immunoreceptor tyrosine-based activation motif phosphorylation and Syk (show SYK Proteins) recruitment.

  4. Activating receptor NKp80 induces cytotoxicity by using an atypical hemi-ITAM amino acid seqeuence and the Syk (show SYK Proteins)-kinase pathway.

  5. NKp80 is expressed on a highly responsive subset of effector memory CD8 (show CD8A Proteins) T cells with an inflammatory NK-like phenotype and promotes T-cell responses toward AICL (show CLEC2B Proteins)-expressing cells.

Chimpanzee Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1) interaction partners

  1. phenotypic, molecular, and functional characterization for triggering molecules (NKp46 (show NCR1 Proteins), NKp30 (show NCR3 Proteins) NKp80, and NKG2D (show KLRK1 Proteins); in this AIDS-resistant species, relevant differences to human NK cells involve NKp80 and particularly NKp30 (show NCR3 Proteins)

Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1) Protein Profile

Protein Summary

KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009

Gene names and symbols associated with KLRF1

  • killer cell lectin-like receptor subfamily F, member 1 (KLRF1)
  • killer cell lectin-like receptor subfamily F, member 1-like (LOC613393)
  • CLEC5C protein
  • KLRF1 protein
  • MGC152582 protein
  • NKp80 protein

Protein level used designations for KLRF1

C-type lectin domain family 5 member C , activating coreceptor NKp80 , killer cell lectin-like receptor F1 , killer cell lectin-like receptor subfamily F member 1 , lectin-like receptor F1 , killer cell lectin-like receptor subfamily F, member 1 , NKp80 receptor

GENE ID SPECIES
51348 Homo sapiens
465281 Pan troglodytes
574389 Macaca mulatta
611429 Canis lupus familiaris
613393 Bos taurus
784491 Bos taurus
100144592 Sus scrofa
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