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anti-Killin, p53-Regulated DNA Replication Inhibitor (KLLN) Antibodies

DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating p53/TP53-induced apoptosis. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KLLN 100144748 B2CW77
KLLN    
KLLN    
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Top anti-KLLN Antibodies at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB KILLIN Antibody (C-term) (ABIN655558) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the KILLIN antibody detected the KILLIN protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of KILLIN Antibody (C-term) in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the KILLIN antibody detected the KILLIN protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

KLLN Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-KLLN Antibodies

  1. Human Polyclonal KLLN Primary Antibody for WB - ABIN655558 : Cho, Liang: Killin is a p53-regulated nuclear inhibitor of DNA synthesis. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 4 references for ABIN655558

More Antibodies against KLLN Interaction Partners

Human Killin, p53-Regulated DNA Replication Inhibitor (KLLN) interaction partners

  1. Germline promoter hypermethylation of KLLN is associated with particular malignant and benign Cowden syndrome features, which is dependent on the PTEN (show PTEN Antibodies) mutation status.

  2. Killin has a role in competitively inhibiting the formation of DNA replication forks during S-phase, as well as potentially negatively regulate RNA synthesis during other cell cycle phases

  3. Data indicate that NVP-BEZ235-induced androgen receptor (AR (show AR Antibodies)) suppression resulted in decreased expression of both tumor suppressor proteins PTEN (show PTEN Antibodies) and KLLN in AR+/ER+ breast cancer cells.

  4. Nuclear KLLN expression associates with improved relapse-free survival for prostate carcinoma

  5. We demonstrate, in vitro and in murine xenograph models, that both KLLN and PTEN (show PTEN Antibodies) are AR-target genes, mediating androgen-induced growth inhibition and apoptosis in breast cancer cells.

  6. Germline KLLN mutations dysregulate the cell cycle at G2.

  7. KLLN is a transcription factor directly regulating AR, TP53 (show TP53 Antibodies), and TP73 (show TP73 Antibodies) expression, with a role in prostate carcinogenesis.

  8. Pathogenic mutations in KLLN are rare in breast cancer families and the c.339_340delAG variant does not represent a high-penetrance breast cancer risk allele.

  9. Cowden syndrome patients have elevated risks of papillary thyroid cancer from KLLN alterations.

  10. 19 of 20 advanced RCC (show XRCC1 Antibodies) showed somatic hypermethylation upstream of KILLIN

KLLN Antigen Profile

Protein Summary

DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating p53/TP53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double- and single- stranded DNA.

Gene names and symbols associated with KLLN

  • killin, p53-regulated DNA replication inhibitor (KLLN) antibody
  • CWS4 antibody
  • KILLIN antibody

Protein level used designations for KLLN

killin

GENE ID SPECIES
100144748 Homo sapiens
Selected quality suppliers for anti-KLLN (KLLN) Antibodies
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