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Kin of IRRE Like (Drosophila) Proteins (NEPH1)

NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). Additionally we are shipping Kin of IRRE Like (Drosophila) Antibodies (46) and Kin of IRRE Like (Drosophila) Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NEPH1 55243 Q96J84
NEPH1 170643 Q80W68
NEPH1 310695 Q6X936
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Top Kin of IRRE Like (Drosophila) Proteins at antibodies-online.com

Showing 8 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
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HOST_HEK-293 Human His tag   0.1 mg Log in to see 2 to 3 Days
$687.50
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HOST_Escherichia coli (E. coli) Mouse Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
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NEPH1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) , ,
,
Rat (Rattus)

Top referenced Kin of IRRE Like (Drosophila) Proteins

  1. Human NEPH1 Protein expressed in Human Cells - ABIN2006642 : MALMO, SHAGASS, DAVIS: A method for the investigation of somatic response mechanisms in psychoneurosis. in Science (New York, N.Y.) 1951 (PubMed)
    Show all 5 references for ABIN2006642

  2. Mouse (Murine) NEPH1 Protein expressed in Human Cells - ABIN2007493 : Sellin, Huber, Gerke, Quack, Pavenstädt, Walz: NEPH1 defines a novel family of podocin interacting proteins. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003 (PubMed)
    Show all 5 references for ABIN2007493

More Proteins for Kin of IRRE Like (Drosophila) (NEPH1) Interaction Partners

Human Kin of IRRE Like (Drosophila) (NEPH1) interaction partners

  1. maintaining high levels of Neph1 at the membrane using a podocyte cell line overexpressing chimeric Neph1 increased the ability of podocytes to resist PAN-induced injury and PAN-induced albumin (show ALB Proteins) leakage

  2. Neph1-CD adopts a global shape in solution, and its interaction with ZO-1 (show TJP1 Proteins) involves multiple sites.

  3. Localization of Neph1 to the podocyte cell membrane is altered in the presence of mutant Myo1c (show MYO1C Proteins), and is actin dependent. Knockdown of Myo1c (show MYO1C Proteins) inhibits Neph1 membrane localization. Neph1 is critical for the maintenance of glomerular function.

  4. A striking finding in this study is the lack of contribution of NEPH1, NPHS1, and NPHS2 genes in 15 Asian families with steroid-resistant nephrotic syndrome.

  5. common variants in LRRC7, KIRREL, NPHS2 and ACTN4 (show ACTN4 Proteins) do not appeear to contribute to susceptibility to diabetic nephropathy in Finnish patients with type 1 diabetes

  6. Neph1 but not nephrin (show NPHS1 Proteins) specifically binds to adaptor protein Grb2 (show GRB2 Proteins) and tyrosine kinase (show TXK Proteins) Csk (show CSK Proteins) in a phosphorylation-dependent manner.

  7. Neph1-Nephrin (show NPHS1 Proteins) proteins bind the Par3 (show F2RL2 Proteins)-Par6 (show PARD6A Proteins)-atypical protein kinase C (show PRKCZ Proteins) (aPKC) complex to regulate podocyte cell polarity

  8. tyrosine phosphorylation of Neph1 mediated by Fyn (show FYN Proteins) results in significantly increased Neph1 and ZO-1 (show TJP1 Proteins) binding, suggesting a critical role for Neph1 tyrosine phosphorylation in reorganizing the Neph1-ZO-1 (show TJP1 Proteins) complex.

Mouse (Murine) Kin of IRRE Like (Drosophila) (NEPH1) interaction partners

  1. Here we demonstrate that Neph1, Neph2, and Neph3 are expressed differentially in various tissues during ontogenesis in mouse and chicken.

  2. Fyn (show FYN Proteins) catalyzes Nephrin (show NPHS1 Proteins) phosphorylation in podocyte detergent-resistant membrane fractions.

  3. nephrin (show NPHS1 Proteins) and Neph1 interact and have roles in glomerular permeability

  4. In the adult brain, Neph1 is seen in the olfactory nerve layer and the glomerular layer of the olfactory bulb, in the hippocampus, and in cerebellar Purkinje cells. At the ultrastructural level, Neph1 is seen in dendritic shafts of pyramidal neurons.

  5. Nephrin-Neph1 complex transduces phosphorylation-mediated signals that assemble an actin polymerization complex at the podocyte intercellular junction.

  6. Neph1-Nephrin (show NPHS1 Proteins) proteins bind the Par3 (show F2RL2 Proteins)-Par6 (show PARD6A Proteins)-atypical protein kinase C (show PRKCZ Proteins) (aPKC) complex to regulate podocyte cell polarity

Kin of IRRE Like (Drosophila) (NEPH1) Protein Profile

Protein Summary

NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2\; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003

Gene names and symbols associated with NEPH1

  • nephrin related (Smp_104390)
  • nephrin related (Smp_140170)
  • kin of IRRE like (Drosophila) (KIRREL)
  • kin of IRRE like (Drosophila) (Kirrel)
  • 6720469N11Rik protein
  • Kirrel1 protein
  • Neph1 protein

Protein level used designations for NEPH1

nephrin related , kin of IRRE-like protein 1 , kin of irregular chiasm-like protein 1 , nephrin-like protein 1 , kin of IRRE like 1 , nephrin 1

GENE ID SPECIES
8340894 Schistosoma mansoni
8353903 Schistosoma mansoni
55243 Homo sapiens
100512834 Sus scrofa
170643 Mus musculus
310695 Rattus norvegicus
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