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Kin of IRRE Like 3 (Drosophila) Proteins (KIRREL3)

The protein encoded by KIRREL3 is a member of the nephrin-like protein family. Additionally we are shipping KIRREL3 Antibodies (33) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KIRREL3 84623 Q8IZU9
KIRREL3 67703 Q8BR86
KIRREL3 315546  
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Top KIRREL3 Proteins at antibodies-online.com

Showing 8 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Rat His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

KIRREL3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) , ,
,
Rat (Rattus)

Top referenced KIRREL3 Proteins

  1. Rat (Rattus) KIRREL3 Protein expressed in Human Cells - ABIN2009338 : Sellin, Huber, Gerke, Quack, Pavenstädt, Walz: NEPH1 defines a novel family of podocin interacting proteins. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003 (PubMed)
    Show all 2 references for ABIN2009338

  2. Mouse (Murine) KIRREL3 Protein expressed in Human Cells - ABIN2007686 : Bhalla, Luo, Buchan, Beachem, Guzauskas, Ladd, Bratcher, Schroer, Balsamo, DuPont, Lilien, Srivastava: Alterations in CDH15 and KIRREL3 in patients with mild to severe intellectual disability. in American journal of human genetics 2008 (PubMed)
    Show all 2 references for ABIN2007686

More Proteins for Kin of IRRE Like 3 (Drosophila) (KIRREL3) Interaction Partners

Human Kin of IRRE Like 3 (Drosophila) (KIRREL3) interaction partners

  1. KIRREL3 interacting proteins MAP1B and MYO16 are potential candidates for intellectual disability and autism spectrum disorder.

  2. Results presented demonstrate for the first time that there are at least 3 splice variants of Kirrel3 expressed in adult human skeletal muscle, two of which have never previously been identified in human muscle.

  3. Alterations in KIRREL3 in patients with mild to severe intellectual disability are reported.

Mouse (Murine) Kin of IRRE Like 3 (Drosophila) (KIRREL3) interaction partners

  1. Kirrel3 is required for formation of hippocampal mossy fiber filopodia; the structures that give rise to dentate granule-GABA synapses and that regulate feed-forward inhibition of CA3 (show CA3 Proteins) neurons.

  2. Kirrel3 has a role in coalescence of vomeronasal sensory neuron axons into glomeruli and in male-male aggression in a resident-intruder assay

  3. Here we demonstrate that Neph1, Neph2, and Neph3 are expressed differentially in various tissues during ontogenesis in mouse and chicken.

  4. Results suggest Neph2 is involved in the nucleogenesis of the pontine nucleus through the control of neuronal migration inside the nucleus.

  5. In the adult brain, Neph2 is seen in the olfactory nerve layer and the glomerular layer of the olfactory bulb, in the hippocampus, and in cerebellar Purkinje cells. At the ultrastructural level, Neph2 is seen in dendritic shafts of pyramidal neurons.

  6. Results suggest that Kirrel3 plays a role in the axonal pathfinding, cell recognition, and synapse formation of DRG neurons on target cells, including the targeting of proprioceptive neurons on muscle spindles through the interaction with nephrin (show NPHS1 Proteins).

KIRREL3 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KIRREL3

  • kin of IRRE like 3 (Drosophila) (KIRREL3)
  • kin of IRRE like 3 (Drosophila) (Kirrel3)
  • 1500010O20Rik protein
  • 2900036G11Rik protein
  • KIRRE protein
  • mKIAA1867 protein
  • MRD4 protein
  • NEPH2 protein
  • PRO4502 protein
  • SST4 protein

Protein level used designations for KIRREL3

kin of IRRE like 3 (Drosophila) , kin of IRRE-like protein 3 , kin of irregular chiasm-like protein 3 , nephrin-like 2 , nephrin-like protein 2 , X kin of IRRE like 3 , membrane protein mKirre

GENE ID SPECIES
489289 Canis lupus familiaris
84623 Homo sapiens
67703 Mus musculus
419719 Gallus gallus
315546 Rattus norvegicus
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