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developing nervous system protein which is a substrate for protein kinase D and a downstream target for both neurotrophin and ephrin receptors. Additionally we are shipping and many more products for this protein.
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Human Polyclonal KIDINS220 Primary Antibody for EIA, WB - ABIN950511
Wu, Bowen: Role of sigma-1 receptor C-terminal segment in inositol 1,4,5-trisphosphate receptor activation: constitutive enhancement of calcium signaling in MCF-7 tumor cells. in The Journal of biological chemistry 2008
Show all 2 references for ABIN950511
Kidins220 binds to the B cell antigen receptor and regulates B cell development and activation.
the existence of novel Kidins220/ARMS splice isoforms with unique properties
The scaffold protein (show HOMER1 Antibodies) Kidins220 associates with brain voltage-gated sodium channels and modulates their activity.
Results suggest a new role of ARMS/Kidins220 as a signaling platform to regulate tumor cell proliferation in response to the extracellular stimuli.
Kidins220/ARMS is expressed in the spleen and peripheral blood of normal BALB/c mice and may participate in the immuno-inflammation of asthma through the nerve growth factor-mediated signaling pathway.
results collectively suggest that ARMS/Kidins220 is a key player in organizing the signaling complex to transduce the extracellular stimuli to cellular responses during dendrite development.
Neurons with altered Kidins220 expression, the constitutive absence of Kidins220 did not affect basal synaptic transmission either in excitatory or inhibitory synapses.
Kidins220 mediates the integration of several growth factor receptor (show RYK Antibodies) pathways during development
Kidins220 has a critical function in the postnatal brain.
Mice heterozygous for kidins220 shows defects in entorhinal cortex and frontal cortex and in water maze learning. Females, not males were affected.
Our results establish the role of ARMS in microglial activation by HIV Tat (show TAT Antibodies)
Kidins220 is expressed in neuroblastoma (show C4orf6 Antibodies) tumors and stabilizes NGF (show NGFB Antibodies)-induced, but not BDNF (show BDNF Antibodies)-induced, survival signaling in neuroblastoma (show ARHGEF16 Antibodies) cell lines.
Kidins220 levels are increased in human brain necropsies from Alzheimer's disease patients. Kidins220 localizes within hyperphosphorylated tau aggregates, and is a substrate for GSK3beta (show GSK3b Antibodies).
Kidins220 depletion is associated with the neural-to Schwann-like transition in neuroblastoma (show ARHGEF16 Antibodies).
Kidins220 is a novel T-cell receptor (TCR)-interacting protein that couples B-Raf to the TCR. Kidins220 is mandatory for sustained Erk signaling and is crucial for TCR-mediated T cell activation.
Kidins220/ARMS is a functional mediator of multiple receptor signalling pathways.
a novel partner of Kidins220/ARMS
induction of morphological polarization in primary T lymphocytes and Jurkat cells enhances Kidins220/ARMS colocalization with ICAM-3 (show ICAM3 Antibodies)
Ankyrin repeat-rich membrane spanning expression, conjunctly with tumour thickness or ulceration, may serve as a prognostic factor in patients with cutaneous melanoma.
developing nervous system protein which is a substrate for protein kinase D and a downstream target for both neurotrophin and ephrin receptors
ankyrin repeat-rich membrane spanning protein
, ankyrin repeat-rich membrane-spanning protein
, kinase D-interacting substance 220
, kinase D-interacting substance of 220 kDa
, kinase D-interacting substrate of 220 kDa
, ankyrin repeat-rich membrane spanning