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In complex with KIF2C, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Additionally we are shipping and and many more products for this protein.
Kif18B is only modestly processive and that the motor switches frequently between directed and diffusive modes of motility.
High KIF18B expression is associated with neoplasms.
Kif18B is a new microtubule dynamics regulatory protein that interacts with EB1 (show MAPRE2 ELISA Kits) to control astral microtubule length
Results uncover a novel role for Aurora A (show AURKA ELISA Kits)/B kinases in regulating spindle MT dynamics through Kif18b-MCAK (show KIF2C ELISA Kits) and suggest that the Kif18b-MCAK (show KIF2C ELISA Kits) complex constitutes the major MT plus-end depolymerizing activity in mitotic cells.
the expression of KIF18B is regulated in a cell cycle-dependent manner and therefore may play an important role(s) in cell division.
In complex with KIF2C, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Its major role may be to transport KIF2C and/or MAPRE1 along microtubules (By similarity).
kinesin-like protein KIF18B
, N-8 kinesin