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Essential for embryonic kidney development.
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KIF26B plays an important role in colorectal carcinogenesis and functions as a novel prognostic indicator and a potential therapeutic target for CRC (show CALR Antibodies).
High expression of KIF26B in breast cancer associates with poor prognosis.
Kif26b, together with Dvl3 (show DVL3 Antibodies)/Daam1 (show DAAM1 Antibodies), initiates cell polarity through the control of planar cell polarity-signaling pathway-dependent activation in endothelial cells.
Kif26b degradation in the metanephric mesenchyme via the ubiquitin-proteasome pathway may be important for proper kidney development.
Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme.
KIF26B may play a role in embryogenesis, specifically in the development of limbs, face, and somites
Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction (By similarity).
kinesin-like protein KIF26B
, N-11 kinesin
, kinesin family protein 26b