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Promotes mitotic spindle assembly. Additionally we are shipping Kinesin Family Member C1 Antibodies (32) and Kinesin Family Member C1 Proteins (4) and many more products for this protein.
Knockdown of KIFC5A dramatically reduces ciliogenesis.
KIFC5A and the Nubp proteins in a common regulatory pathway involved in the control of centrosome duplication in mammalian cells.
Low post translational modifications of KIFC1 protein is associated with neoplasms.
KIFC1 is overexpressed in GC.
Association of KIFC1 gene expression and centrosome amplification with high-grade serous ovarian carcinoma.
stabilization of the centrosome-spindle pole interface by the CEP215 (show CDK5RAP2 ELISA Kits)-HSET complex could promote survival of cancer cells containing supernumerary centrosomes.
KIFC1 silencing significantly reduces breast cancer cell viability.
Data provides the first evidence of centrosome clustering-independent activities of HSET that fuel tumor progression.
We show that some are new substrates of the anaphase-promoting complex/cyclosome and validate KIFC1 and RacGAP1/Cyk4 as two such targets involved respectively in timely mitotic spindle disassembly and cell spreading
Our data underscore KIFC1 as a putative biomarker that predicts worse prognosis, poor overall survival and may serve as a potential marker of onset of metastatic dissemination in ovarian cancer patients.
Study demonstrates microtubule tip-tracking of human kinesin-14 HSET and show that EB1 (show MAPRE2 ELISA Kits) is sufficient to induce this dynamic microtubule end localization.
Acentrosomal spindle assembly mechanisms are hyperactive in cancer cells and promote HSET.
Promotes mitotic spindle assembly.
, kinesin-like protein 2
, kinesin-like protein KIFC1
, kinesin-related protein HSET
, kinesin family c-terminal 5A
, kinesin family c-terminal 5B
, kinesin family member C5A
, kinesin-related protein KIFC5A
, kinesin-related protein 1
, kinesin-related protein KRP1
, carboxy-terminal kinesin 2
, XCTK2-like motor protein
, kinesin family member C1
, kinesin-like protein KIFC1-like
, kinesin motor protein KIFC4
, kinesin-like 2a