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Kinesin is a molecular motor that generates ATP-dependent movement of vesicles and organelles along microtubules. Additionally we are shipping KLC2 Kits (7) and KLC2 Proteins (7) and many more products for this protein.
Showing 10 out of 56 products:
Human Polyclonal KLC2 Primary Antibody for FACS, IHC (p) - ABIN656175
Trejo, Lecuona, Grillo, Szleifer, Nekrasova, Gelfand, Sznajder: Role of kinesin light chain-2 of kinesin-1 in the traffic of Na,K-ATPase-containing vesicles in alveolar epithelial cells. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010
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Human Polyclonal KLC2 Primary Antibody for FACS, IHC (p) - ABIN953086
Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications. in Molecular & cellular proteomics : MCP 2007
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Human Polyclonal KLC2 Primary Antibody for EIA, FACS - ABIN953087
Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006
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Human Polyclonal KLC2 Primary Antibody for ICC, IF - ABIN4329089
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
a homozygous 216-bp deletion located at the non-coding upstream region of the KLC2 gene in patients with SPOAN syndrome causes overexpression of the gene
Results identified KLC2 as a novel target and of miR (show MLXIP Antibodies)-125b in non-small-cell lung cancer (NSCLC) and show the oncogenic potential of KLC2 in the progression of NSCLC.
For the binding of cargos shared by KLC2, we propose a different site located within the groove but not involving N343.
Na,K-ATPase (show ATP1A1 Antibodies) traffic toward the plasma membrane in alveolar epithelial cells is driven by kinesin-1, where KLC2 is the isoform regulating this process.
KLC2 is a cellular target of GSK-3beta (show GSK3b Antibodies) capable of regulating synaptic plasticity, particularly AMPA (show GRIA3 Antibodies) receptor trafficking, as well as mood-associated behaviors in animal models
Kinesin is a molecular motor that generates ATP-dependent movement of vesicles and organelles along microtubules. Kinesin consists of 2 light chains, such as KLC2, and 2 heavy chains (see KIF5B\; MIM 602809) in a 1:1 stoichiometric ratio (Rahman et al., 1998
kinesin light chain 2
, KLC 2