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Kinesin is a molecular motor that generates ATP-dependent movement of vesicles and organelles along microtubules. Additionally we are shipping KLC2 Proteins (7) and many more products for this protein.
Showing 10 out of 58 products:
Human Polyclonal KLC2 Primary Antibody for ICC, IF - ABIN4329089
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Human Polyclonal KLC2 Primary Antibody for FACS, IHC (p) - ABIN656175
Trejo, Lecuona, Grillo, Szleifer, Nekrasova, Gelfand, Sznajder: Role of kinesin light chain-2 of kinesin-1 in the traffic of Na,K-ATPase-containing vesicles in alveolar epithelial cells. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010
Show all 4 Pubmed References
a homozygous 216-bp deletion located at the non-coding upstream region of the KLC2 gene in patients with SPOAN syndrome causes overexpression of the gene
Results identified KLC2 as a novel target and of miR (show MLXIP Antibodies)-125b in non-small-cell lung cancer (NSCLC) and show the oncogenic potential of KLC2 in the progression of NSCLC.
For the binding of cargos shared by KLC2, we propose a different site located within the groove but not involving N343.
Na,K-ATPase (show ATP1A1 Antibodies) traffic toward the plasma membrane in alveolar epithelial cells is driven by kinesin-1, where KLC2 is the isoform regulating this process.
structural plasticity of the N-terminal capping helix might represent a structural determinant for TPR domain structural versatility in cargo binding
KLC2 is a cellular target of GSK-3beta (show GSK3b Antibodies) capable of regulating synaptic plasticity, particularly AMPA (show GRIA3 Antibodies) receptor trafficking, as well as mood-associated behaviors in animal models
Kinesin is a molecular motor that generates ATP-dependent movement of vesicles and organelles along microtubules. Kinesin consists of 2 light chains, such as KLC2, and 2 heavy chains (see KIF5B\; MIM 602809) in a 1:1 stoichiometric ratio (Rahman et al., 1998
kinesin light chain 2
, KLC 2