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KLC3 encodes a member of the kinesin light chain gene family. Additionally we are shipping KLC3 Antibodies (35) and many more products for this protein.
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Microtubule-bound kinesin-1 and kinesin-3 motor domains were visualized at multiple steps in their ATPase cycles--including their nucleotide-free states--at approximately 7 A resolution using cryo-electron microscopy.
Rat KLC3 interacts with KHC and microtubules in vitro. Expressed in spleen, intestine, brain, ovary, testis. Testis expression restricted to post-meiotic spermatids.
Rat KLC3 associates with the outer dense fibers (show ODF1 Proteins) of maturing sperm tails.
KLC3 plays a role during spermiogenesis in the development of the midpiece and in the normal function of spermatozoa
This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.
kinesin light chain 3
, kinesin light chain 2
, kinesin light chain KLCt