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Kruppel-like zinc finger transcription factor; involved in TGFbeta-mediated signaling cascades to the regulation of pancreatic epithelial cell growth. Additionally we are shipping and and many more products for this protein.
Showing 10 out of 65 products:
Human Polyclonal KLF10 Primary Antibody for EIA, IHC (p) - ABIN360044
Fueki, Sagara, Akimoto, Ota, Okada, Sugiyama, Fueki, Makino, Fukuda: Interleukin-10 regulates transforming growth factor-beta signaling in cultured human bronchial epithelial cells. in Respiration; international review of thoracic diseases 2007
Show all 4 references for ABIN360044
Human Polyclonal KLF10 Primary Antibody for EIA, WB - ABIN953089
Kim, Shin, Subramaniam, Bruinsma, Kim, Hawse, Spelsberg, Janknecht: Histone demethylase JARID1B/KDM5B is a corepressor of TIEG1/KLF10. in Biochemical and biophysical research communications 2010
Show all 3 references for ABIN953089
Human Polyclonal KLF10 Primary Antibody for IHC (p), WB - ABIN392159
Hawse, Subramaniam, Monroe, Hemmingsen, Ingle, Khosla, Oursler, Spelsberg: Estrogen receptor beta isoform-specific induction of transforming growth factor beta-inducible early gene-1 in human osteoblast cells: an essential role for the activation function 1 domain. in Molecular endocrinology (Baltimore, Md.) 2008
Show all 3 references for ABIN392159
Dog (Canine) Polyclonal KLF10 Primary Antibody for WB - ABIN2780705
Reinholz, An, Johnsen, Subramaniam, Suman, Ingle, Roche, Spelsberg: Differential gene expression of TGF beta inducible early gene (TIEG), Smad7, Smad2 and Bard1 in normal and malignant breast tissue. in Breast cancer research and treatment 2004
Cow (Bovine) Polyclonal KLF10 Primary Antibody for WB - ABIN2777948
Ivanov, Ivanova, Salnikow, Timofeeva, Subramaniam, Lerman: Two novel VHL targets, TGFBI (BIGH3) and its transactivator KLF10, are up-regulated in renal clear cell carcinoma and other tumors. in Biochemical and biophysical research communications 2008
TIEG-1 overexpression in normal human skin fibroblasts results in improved resistance to oxidative stress
CDK2 (show CDK2 Antibodies) up-regulates the protein level of KLF10 through reducing its association with SIAH1 (show SIAH1 Antibodies), a KLF10 E3-ubiqutin ligase involved in proteasomal degradation.
KLF10 directly binds to TGF-BRII promoter in T cells, leading to enhanced gene expression.
The tumor suppressor function of LSAMP (show LSAMP Antibodies) is most likely exerted by reducing the proliferation rate of the tumor cells, possibly by indirectly upregulating one or more of the genes HES1, CTAG2 (show CTAG2 Antibodies) or KLF10.
KLF10, functions as a toggle to integrate antagonistic signals regulating FOXP3 (show FOXP3 Antibodies) via Sin3-HDAC (show HDAC3 Antibodies)/PCAF (show KAT2B Antibodies) pathway and, thus, immune activation.
RAF-1 (show RAF1 Antibodies) phosphorylation and PIN1 (show PIN1 Antibodies) isomerization together regulate KLF10 stability and further affect the role of KLF10 in tumor progression.
KLF10 is an effective repressor of myoblast proliferation and represses FGFR1 (show FGFR1 Antibodies) promoter activity in these cells via an Sp1 (show PSG1 Antibodies) binding site.
KLF10 may constitute a pharmacogenomic marker to discriminate between response and nonresponse to hydroxyurea treatment in beta-hemoglobinopathy patients.
KLF10 is a potential clinical predictor for progression of pancreatic cancer.
study identified 6 novel, hypertrophic cardiomyopathy associated TIEG1 missense variants and have demonstrated that a number of these variants have abnormal function with regard to mutant TIEG1's ability to regulate either the PTTG1 (show PTTG1 Antibodies) or SMAD7 (show SMAD7 Antibodies) promoters
our findings indicate that the absence of TIEG1 plays a cardioprotective role in ischaemic heart disease by promoting changes in Pten (show PTEN Antibodies)/Akt (show AKT1 Antibodies) signalling.
Klf10 is involved in tooth development and promotes odontoblastic differentiation via the up-regulation of Dmp1 (show DMP1 Antibodies) and Dspp (show DSPP Antibodies) transcription.
Decreased expression of Osterix (show SP7 Antibodies), as well as impaired TGFbeta (show TGFB1 Antibodies) and BMP2 (show BMP2 Antibodies) signaling, contribute to the observed osteopenic bone phenotype of TIEG1 KO mice.
KLF10 deficiency predisposes to colitis through epigenetic regulation of TGFBRII expression and colonic macrophage dysregulation.
The KLF10 KO condition may reinforce the TGF-betaSmad signaling pathway.
TGFbeta2 regulates hypothalamic TRH (show TRH Antibodies) expression through TIEG1 during fetal development.
these data implicate an important role for TIEG1 in mediating estrogen signaling throughout the mouse skeleton and suggest that defects in this pathway are likely to contribute to the sex-specific osteopenic phenotype
up-regulation of KLF10 was accompanied by increased TGFbeta (show TGFB1 Antibodies) signaling genes and suppressed ChREBP (show MLXIPL Antibodies) expression. These observations suggest possible association of KLF10 and NASH (show SAMSN1 Antibodies) progression
To explore the role of KLF10 as an antiinflammatory factor in skin inflammation, we employed the phthalic anhydride-induced dermatitis model. These results support the role of KLF10 as an anti-inflammatory factor in chemical-induced skin inflammation.
Kruppel-like zinc finger transcription factor; involved in TGFbeta-mediated signaling cascades to the regulation of pancreatic epithelial cell growth
Kruppel-like factor 10
, Krueppel-like factor 10
, TGFB-inducible early growth response protein 1
, early growth response-alpha
, transforming growth factor-beta-inducible early growth response protein 1
, zinc finger transcription factor TIEG
, TGF-beta inducible early growth response protein 1
, GDNF-inducible factor
, TGFB inducible early growth response 1
, transcription factor GIF
, TGFB inducible early growth response
, zinc finger transcription factor homolog CPG20