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Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. Additionally we are shipping KLF2 Kits (7) and KLF2 Proteins (6) and many more products for this protein.
Showing 10 out of 95 products:
Chicken Polyclonal KLF2 Primary Antibody for IHC, WB - ABIN2777573
Saavedra, Patterson, West, Randell, Riches, Malcolm, Cool, Nick, Dinarello: Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways. in American journal of respiratory cell and molecular biology 2008
Show all 2 references for ABIN2777573
Human Polyclonal KLF2 Primary Antibody for IF (p), IHC (p) - ABIN680473
Wang, Wang, Shen, Yin, Tang: Effects of artesunate and ursolic acid on hyperlipidemia and its complications in rabbit. in European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2013
Show all 2 references for ABIN680473
Human Monoclonal KLF2 Primary Antibody for ELISA, WB - ABIN523760
Richardson, Jadlowsky, Didigu, Doms, Riley: Kruppel-like factor 2 modulates CCR5 expression and susceptibility to HIV-1 infection. in Journal of immunology (Baltimore, Md. : 1950) 2012
Human Polyclonal KLF2 Primary Antibody for WB - ABIN2780291
Basu, Morris, Haar, Wani, Lingrel, Gaensler, Lloyd: KLF2 is essential for primitive erythropoiesis and regulates the human and murine embryonic beta-like globin genes in vivo. in Blood 2005
Human Polyclonal KLF2 Primary Antibody for WB - ABIN1538992
Gan, Dang, Han, Ling, Duan, Liu, Xu: ERK5/HDAC5-mediated, resveratrol-, and pterostilbene-induced expression of MnSOD in human endothelial cells. in Molecular nutrition & food research 2015
Authors show that KLF2 induces the expression of CRABP2 (show CRABP2 Antibodies) and RARgamma and inhibits the expression FABP5 (show FABP5 Antibodies) and PPARbeta (show PPARD Antibodies)/delta thereby shifting RA signaling from the pro-carcinogenic FABP5 (show FABP5 Antibodies)/PPARbeta (show PPARD Antibodies)/delta to the growth-suppressing CRABP2 (show CRABP2 Antibodies)/RAR (show RARA Antibodies) path.
MicroRNA-30 mediates anti-inflammatory effects of shear stress and KLF2 via repression of Ang2 (show ANGPT2 Antibodies).
In hyperuricemia, miR (show MLXIP Antibodies)-92a downregulation increased KLF2 expression, subsequently inhibiting VEGFA (show VEGFA Antibodies), which resulted in decreased angiogenesis.
These data provide support for a continuous role of KLF2 in stabilizing the vessel wall via co-temporal expression of eNOS and AQP1 both preceding and during the pathogenesis of atherosclerosis.
These results indicate that the KDM3A (show KDM3A Antibodies)-KLF2-IRF4 (show IRF4 Antibodies) pathway plays an essential role in multiple myeloma cell survival and homing to the bone marrow, and therefore represents a therapeutic target.
Expression of KLF4 (show KLF4 Antibodies) in mononuclear leukocytes positively correlates with cellular markers of immune activation, whereas KLF2 expression negatively correlates with markers of subclinical atherosclerosis in this HIV-infected population.
TUG1 overexpression was induced by nuclear transcription factor SP1 (show SP1 Antibodies) and TUG1 could epigeneticly repress Kruppel-like factor 2 (KLF2) transcription in HCC (show FAM126A Antibodies) cells by binding with PRC2 and recruiting it to KLF2 promoter region.
studies identify gain of MEKK3 sig (show MAP3K3 Antibodies)nalling and KL (show KLF4 Antibodies)F2/4 function as causal mechanisms for cerebral cavernous malformations pathogenesis that may be targeted to develop new CCM therapeutics
In conclusion, KLF2 suppressed the angiogenesis of LSECs through inhibition of cell proliferation, migration, and vessel tube formation.
TINCR could bind to STAU1 (staufen1 (show STAU1 Antibodies)) protein, and influence KLF2 mRNA stability and expression
miR (show MYLIP Antibodies)-92a coregulates KLF4 (show KLF4 Antibodies) and KLF2 expression in arterial endothelium and contributes to phenotype heterogeneity associated with regional atherosusceptibility and protection in vivo.
KLF2 knockdown markedly reduced expression of miR (show MLXIP Antibodies)-155 in macrophages and macrophage activation.
study therefore establishes the pivotal role of Klf2 and Tfcp2l1 (show TFCP2L1 Antibodies) in mediating ESC self-renewal promoted by Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.
endothelial-specific loss of Mekk3 (show MAP3K3 Antibodies), Klf2 or Klf4 (show KLF4 Antibodies) markedly prevents cerebral cavernous malformation lesion formation, reverses the increase in Rho activity, and rescues lethality
knockdown of Klf2 expression in endothelial cells induced more endothelial cell injury in early diabetic nephropathy
Cineromycin B inhibited adipocyte differentiation in 3T3-L1 cells mainly via upregulation of KLF2 and KLF3 (show KLF3 Antibodies) mRNA expression at an early stage of the differentiation.
Data reveal a novel role of HDAC5 (show HDAC5 Antibodies) in modulating the KLF2 transcriptional activation and eNOS (show NOS3 Antibodies) expression.
inhibition of leukocyte adhesion by Myocyte enhancer factor 2 C was partially mediated by induction of KLF2
KLF2 is pivotal for coordinating CD4 (show CD4 Antibodies)(+) T cell differentiation through two distinct and complementary mechanisms: via control of T cell localization and by regulation of lineage-defining transcription factors.
The Kruppel-like factor 2 (Klf2) is phosphorylated by Erk2 (show MAPK1 Antibodies) and that phospho-Klf2 is proteosomally degraded.
reveals a beta1 integrin-Klf2-Egfl7 (show EGFL7 Antibodies)-signaling pathway that is tightly regulated by cerebral cavernous malformation proteins
KLF2 and ERG (show ERG Antibodies) associate in a physical complex and the two proteins synergistically activate transcription of Flk1 (show KDR Antibodies).
Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1\; MIM 601974) and the selectin CD62L (SELL\; MIM 153240) (summary by Weinreich et al., 2009
Kruppel-like factor 2 (lung)
, Krueppel-like factor 2
, Kruppel-like factor LKLF
, lung Kruppel-like zinc finger transcription factor
, lung krueppel-like factor
, lung Kruppel-like factor