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a transcription factor that works with Sp1 to activate the Laminin gamma1 chain gene [RGD, Feb 2006].. Additionally we are shipping KLF4 Proteins (15) and KLF4 Kits (6) and many more products for this protein.
Showing 10 out of 267 products:
Human Polyclonal KLF4 Primary Antibody for WB - ABIN656007
Guan, Xie, Leithäuser, Flossbach, Möller, Wirth, Ushmorov: KLF4 is a tumor suppressor in B-cell non-Hodgkin lymphoma and in classic Hodgkin lymphoma. in Blood 2010
Show all 3 references for ABIN656007
Human Polyclonal KLF4 Primary Antibody for FACS, IF - ABIN655898
Wong, Hou, Tseng, Chien, Wu, Chen, Ho, Kyo, Teng: Krüppel-like transcription factor 4 contributes to maintenance of telomerase activity in stem cells. in Stem cells (Dayton, Ohio) 2010
Show all 3 references for ABIN655898
Human Polyclonal KLF4 Primary Antibody for IF, WB - ABIN389190
Alder, Georgantas, Hildreth, Kaplan, Morisot, Yu, McDevitt, Civin: Kruppel-like factor 4 is essential for inflammatory monocyte differentiation in vivo. in Journal of immunology (Baltimore, Md. : 1950) 2008
Show all 2 references for ABIN389190
Human Monoclonal KLF4 Primary Antibody for EIA, IHC (p) - ABIN336104
Yan, Liu, Liu, Zhao: KLF4: a novel target for the treatment of atherosclerosis. in Medical hypotheses 2008
Show all 2 references for ABIN336104
Human Polyclonal KLF4 Primary Antibody for DB, IF - ABIN390035
Behr, Deller, Godmann, Müller, Bergmann, Ivell, Steger: Kruppel-like factor 4 expression in normal and pathological human testes. in Molecular human reproduction 2007
Show all 2 references for ABIN390035
Human Polyclonal KLF4 Primary Antibody for WB - ABIN2776415
Yoon, Ghaleb, Nandan, Hisamuddin, Dalton, Yang: Krüppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage. in Oncogene 2005
Cow (Bovine) Polyclonal KLF4 Primary Antibody for EIA, WB - ABIN782911
Shields, Christy, Yang: Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest. in The Journal of biological chemistry 1996
Chicken Polyclonal KLF4 Primary Antibody for IHC, WB - ABIN2780577
Natesampillai, Kerkvliet, Leung, Veldhuis: Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells. in American journal of physiology. Endocrinology and metabolism 2008
zebrafih Klf4a is essential for the repression of intestinal cell proliferation
Proper heart valve formation in zebrafish critically depends on protein kinase D2 (show PKD2 Antibodies)-histone deacetylase 5 (show HDAC5 Antibodies)-Kruppel-like factor signaling.
Findings suggest that, in obese status, the lower expression level of A2bAR, KLF4, and KLF15 of visceral adipose tissue may correlate with obese-dyslipidemia induced inflammation in Uygur population.
Data demonstrated that miR (show MLXIP Antibodies)-92a may play a positive role in the colorectal carcinogenesis by promoting the proliferation and migration of CRC (show CALR Antibodies) cells through targeting KLF4 as well as downstream p21 (show CDKN1A Antibodies).
Study demonstrates that KLF4 plays a significant role in the pathogenesis of colorectal neoplasia.
we show that the two PAX6 (show PAX6 Antibodies) isoforms differentially and cooperatively regulate the expression of genes specific to the structure and functions of the corneal epithelium, particularly keratin 3 (KRT3) and keratin 12 (KRT12 (show KRT12 Antibodies)). PAX6 (show PAX6 Antibodies) isoform-a induced KRT3 expression by targeting its upstream region. KLF4 enhanced this induction. A combination of PAX6 (show PAX6 Antibodies) isoform-b, KLF4, and OCT4 (show POU5F1 Antibodies) induced KRT12 (show KRT12 Antibodies) expression
we sequenced KLF4 in approximately 1000 NSCL (show NHLH1 Antibodies)/P cases and 300 controls. By one statistical test, missense variants of KLF4 as a group were enriched in cases versus controls. Moreover, two patient-derived KLF4 variants disrupted periderm differentiation upon forced expression in zebrafish embryos, suggesting that they have dominant-negative effect.
A novel method using an inactivated viral particle to package and deliver four purified recombinant Yamanaka transcription factors (Sox2 (show SOX2 Antibodies), Oct4 (show POU5F1 Antibodies), Klf4, and c-Myc (show MYC Antibodies)) resulting in reprogramming of human primary fibroblasts has been described.
CXCR4 (show CXCR4 Antibodies) was co-expressed with all investigated neural and embryonic stem cell markers in both primary and recurrent tissues, whereas CXCR7 (show CXCR7 Antibodies) was mostly found on stem cell marker-negative cells, but was co-expressed with KLF-4 on a distinct GBM cell subpopulation
findings suggest that KLF4 may represent a potential biomarker for EC dysfunction
KLF4 might play Janus-faced roles in oral squamous cell carcinoma, acting both as a tumor suppressor and as an oncogene (show RAB1A Antibodies).
The p53 (show TP53 Antibodies)-KLF4-CEBPA (show CEBPA Antibodies) axis is deregulated in AML (show RUNX1 Antibodies) but can be functionally restored by conventional chemotherapy and novel p53 (show TP53 Antibodies) activating treatments.
Klf4 is transcribed both maternally and zygotically and the transcript is ubiquitous in embryos during germ-layer formation
Data show that the reprogramming factors OCT4 (show POU5F1 Antibodies), SOX2 (show SOX2 Antibodies), KLF4, and MYC (show MYC Antibodies) (OSKM) drive cells along two distinct and parallel pathways, one pluripotent and one endodermal.
our study provides valuable information on the molecular interactions between OSKM(Oct4 (show POU5F1 Antibodies), Sox2 (show SOX2 Antibodies), Klf4, and Myc (show MYC Antibodies)) and cofactors and molecular mechanisms for the functional importance of Set1a (show SETD1A Antibodies) in ESCs (show NR2E3 Antibodies) and early development
Data show that R-Smad Proteins SMAD1 and SMAD5, which transduce bone morphogenetic protein (BMP) signals, recognize enhancer regions together with Kruppel-like factors KLF4 and KLF5 in naive embryonic stem cell (mESCs).
Results suggest that Kruppel-like factor 4 is not required for retinal cell differentiation or survival. Data support a hypothesis that KLF4 suppresses axon growth during development.
KLF4 is a master regulator of EndMT in CCM pathology; thus, the inhibition of Klf4 expression may have a therapeutic role in limiting CCM appearance and progression.
Authors show that absence of Klf4 accelerates carcinogenesis and correlates with the absence of cytokeratin 1 (show KRT1 Antibodies) expression. Results suggest a potential role for KLF4 as a tumor suppressor gene for the tongue epithelium.
KLF-4 was downregulated in the TGF-beta (show TGFB1 Antibodies)-induced EMT (show ITK Antibodies) model in LA-4 cells. KLF-4 overexpression markedly reduced the PAI-1 (show SERPINE1 Antibodies) expression and inhibited the TGF-beta (show TGFB1 Antibodies)-induced EMT (show ITK Antibodies) .
Data show that CCAAT-enhancer-binding protein-alpha (C/EBPalpha (show CEBPA Antibodies)) directly regulates Kruppel-like factor 4 (Klf4) expression and increasing the levels of histone demethylase (show MBD2 Antibodies) Lsd1 (show KDM1A Antibodies) and transcription factor Brd4 (show BRD4 Antibodies) in B cell.
Angiotensin II can modulate epigenetic regulation in podocytes and renin (show REN Antibodies)-angiotensin blockade inhibits these actions in part via KLF4 in proteinuric kidney diseases.
miR (show MYLIP Antibodies)-92a coregulates KLF4 and KLF2 (show KLF2 Antibodies) expression in arterial endothelium and contributes to phenotype heterogeneity associated with regional atherosusceptibility and protection in vivo.
a transcription factor that works with Sp1 to activate the Laminin gamma1 chain gene
Krueppel-like factor 4
, Kruppel-like transcription factor 4a
, Kruppel-like factor 4 (gut)
, Kruppel-like factor 4
, endothelial Kruppel-like zinc finger protein
, epithelial zinc finger protein EZF
, gut-enriched krueppel-like factor
, Kruppel-like transcription factor
, blood island enriched kruppel like factor
, Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF)