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a transcription factor that works with Sp1 to activate the Laminin gamma1 chain gene [RGD, Feb 2006].. Additionally we are shipping KLF4 Proteins (17) and KLF4 Kits (5) and many more products for this protein.
Showing 10 out of 260 products:
Human Polyclonal KLF4 Primary Antibody for WB - ABIN656007
Guan, Xie, Leithäuser, Flossbach, Möller, Wirth, Ushmorov: KLF4 is a tumor suppressor in B-cell non-Hodgkin lymphoma and in classic Hodgkin lymphoma. in Blood 2010
Show all 3 references for ABIN656007
Human Polyclonal KLF4 Primary Antibody for FACS, IF - ABIN655898
Wong, Hou, Tseng, Chien, Wu, Chen, Ho, Kyo, Teng: Krüppel-like transcription factor 4 contributes to maintenance of telomerase activity in stem cells. in Stem cells (Dayton, Ohio) 2010
Show all 3 references for ABIN655898
Human Polyclonal KLF4 Primary Antibody for IF, WB - ABIN389190
Alder, Georgantas, Hildreth, Kaplan, Morisot, Yu, McDevitt, Civin: Kruppel-like factor 4 is essential for inflammatory monocyte differentiation in vivo. in Journal of immunology (Baltimore, Md. : 1950) 2008
Show all 2 references for ABIN389190
Human Monoclonal KLF4 Primary Antibody for EIA, IHC (p) - ABIN336104
Yan, Liu, Liu, Zhao: KLF4: a novel target for the treatment of atherosclerosis. in Medical hypotheses 2008
Show all 2 references for ABIN336104
Human Polyclonal KLF4 Primary Antibody for DB, IF - ABIN390035
Behr, Deller, Godmann, Müller, Bergmann, Ivell, Steger: Kruppel-like factor 4 expression in normal and pathological human testes. in Molecular human reproduction 2007
Show all 2 references for ABIN390035
Human Polyclonal KLF4 Primary Antibody for WB - ABIN2776415
Yoon, Ghaleb, Nandan, Hisamuddin, Dalton, Yang: Krüppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage. in Oncogene 2005
Cow (Bovine) Polyclonal KLF4 Primary Antibody for EIA, WB - ABIN782911
Shields, Christy, Yang: Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest. in The Journal of biological chemistry 1996
Chicken Polyclonal KLF4 Primary Antibody for IHC, WB - ABIN2780577
Natesampillai, Kerkvliet, Leung, Veldhuis: Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells. in American journal of physiology. Endocrinology and metabolism 2008
zebrafih Klf4a is essential for the repression of intestinal cell proliferation
Proper heart valve formation in zebrafish critically depends on protein kinase D2 (show PKD2 Antibodies)-histone deacetylase 5 (show HDAC5 Antibodies)-Kruppel-like factor signaling.
The p53 (show TP53 Antibodies)-KLF4-CEBPA (show CEBPA Antibodies) axis is deregulated in AML (show RUNX1 Antibodies) but can be functionally restored by conventional chemotherapy and novel p53 (show TP53 Antibodies) activating treatments.
Several novel and known AKT (show AKT1 Antibodies) phosphorylation sites are identified within OCT4 (show POU5F1 Antibodies), SOX2 (show SOX2 Antibodies) and KLF4.
KLF4 is probably repressed by histone acetylation in lung cancer.
The dysregulated KLF4/HNF-6 (show ONECUT1 Antibodies) pathway drives dedifferentition and progression of HCC (show FAM126A Antibodies).
Overexpression of KLF4 inhibited virus-induced activation of ISRE and IFN-b promoter in cells, while knockdown of KLF4 potentiated viral infection-triggered induction of IFNB1 (show IFNB1 Antibodies) and downstream genes and attenuated viral replication.
these are the first two cases reported of the simultaneous occurrence of secretory meningiomas with mutation of KLF4 in collision with a glioblastoma and an anaplastic astrocytoma, respectively
KLF4-regulated drug resistance might, at least partially, positively regulate high-mobility group box 1 (HMGB1 (show HMGB1 Antibodies)), which is a significant contributor to chemoresistance in osteosarcoma cells
Authors demonstrate that F-box only protein 22 (FBXO22 (show FBXO22 Antibodies)) interacts with and thereby destabilizes KLF4 via polyubiquitination. As a result, FBXO22 (show FBXO22 Antibodies) could promote HCC (show FAM126A Antibodies) cells proliferation.
Angiotensin II can modulate epigenetic regulation in podocytes and renin (show REN Antibodies)-angiotensin blockade inhibits these actions in part via KLF4 in proteinuric kidney diseases.
Arginine methylation of KLF4 by PRMT5 (show PRMT5 Antibodies) inhibits KLF4 ubiquitylation by VHL (show VHL Antibodies) and thereby reduces KLF4 turnover.
Klf4 is transcribed both maternally and zygotically and the transcript is ubiquitous in embryos during germ-layer formation
Results suggest that Kruppel-like factor 4 is not required for retinal cell differentiation or survival. Data support a hypothesis that KLF4 suppresses axon growth during development.
KLF4 is a master regulator of EndMT in CCM pathology; thus, the inhibition of Klf4 expression may have a therapeutic role in limiting CCM appearance and progression.
Authors show that absence of Klf4 accelerates carcinogenesis and correlates with the absence of cytokeratin 1 (show KRT1 Antibodies) expression. Results suggest a potential role for KLF4 as a tumor suppressor gene for the tongue epithelium.
KLF-4 was downregulated in the TGF-beta (show TGFB1 Antibodies)-induced EMT (show ITK Antibodies) model in LA-4 cells. KLF-4 overexpression markedly reduced the PAI-1 (show SERPINE1 Antibodies) expression and inhibited the TGF-beta (show TGFB1 Antibodies)-induced EMT (show ITK Antibodies) .
Data show that CCAAT-enhancer-binding protein-alpha (C/EBPalpha (show CEBPA Antibodies)) directly regulates Kruppel-like factor 4 (Klf4) expression and increasing the levels of histone demethylase (show MBD2 Antibodies) Lsd1 (show KDM1A Antibodies) and transcription factor Brd4 (show BRD4 Antibodies) in B cell.
Data indicate that miR (show MLXIP Antibodies)-25 is a novel negative regulator of adipocyte differentiation and it suppressed 3T3-L1 adipogenesis by targeting KLF4 and C/EBPalpha (show CEBPA Antibodies), which provides novel insights into the molecular mechanism of miRNA-mediated cellular differentiation.
transcriptional cooperation between GR and Klf4 may determine cell-type specific gene expression regulation
unravels a novel mechanism how matrix stiffness regulates cellular proliferation and highlights the importance of matrix stiffness-modulated Klf5 (show KLF5 Antibodies)/Klf4 in the regulation of renal physiologic functions and fibrosis progression
endothelial-specific loss of Mekk3 (show MAP3K3 Antibodies), Klf2 (show KLF2 Antibodies) or Klf4 markedly prevents cerebral cavernous malformation lesion formation, reverses the increase in Rho activity, and rescues lethality
miR (show MYLIP Antibodies)-92a coregulates KLF4 and KLF2 (show KLF2 Antibodies) expression in arterial endothelium and contributes to phenotype heterogeneity associated with regional atherosusceptibility and protection in vivo.
a transcription factor that works with Sp1 to activate the Laminin gamma1 chain gene
Krueppel-like factor 4
, Kruppel-like transcription factor 4a
, Kruppel-like factor 4 (gut)
, Kruppel-like factor 4
, endothelial Kruppel-like zinc finger protein
, epithelial zinc finger protein EZF
, gut-enriched krueppel-like factor
, Kruppel-like transcription factor
, blood island enriched kruppel like factor
, Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF)