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anti-Kruppel-Like Factor 8 (KLF8) Antibodies

KLF8 encodes a protein which is a member of the Sp/KLF family of transcription factors. Additionally we are shipping KLF8 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KLF8 11279 O95600
KLF8 245671 Q8BLM0
KLF8 302582  
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Top anti-KLF8 Antibodies at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-KLF8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:2500Positive Control: Human Kidney 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-KLF8 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate Host: Rabbit  Target Name: KLF8  Sample Tissue: HepG2 Whole Cell lysates  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-KLF8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Placenta 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB ABIN184763 staining (2µg/ml) of Human Kidney lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB Anti-KLF8 antibody, Western blotting Lane 1: SMMC Cell Lysate Lane 2: 293T Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC, WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of KLF8 expression in transfected 293T cell line by KLF8 MaxPab polyclonal antibody.Lane 1: KLF8 transfected lysate(39.49 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to KLF8 on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 9 Days
$430.00
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Small Intestine, Submucosal Plexus: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details

KLF8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
, ,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-KLF8 Antibodies

  1. Human Polyclonal KLF8 Primary Antibody for IHC, WB - ABIN2777342 : Lossi, Laugier-Anfossi, Depetris, Gecz, Gedeon, Kooy, Schwartz, Mattei, Croquette, Villard: Abnormal expression of the KLF8 (ZNF741) gene in a female patient with an X;autosome translocation t(X;21)(p11.2;q22.3) and non-syndromic mental retardation. in Journal of medical genetics 2002 (PubMed)
    Show all 4 references for ABIN2777342

  2. Human Polyclonal KLF8 Primary Antibody for IF, WB - ABIN524708 : Schnell, Romagna, Jaehnert, Albrecht, Eigenbrod, Juerchott, Kretzschmar, Tonn, Schichor: Krüppel-like factor 8 (KLF8) is expressed in gliomas of different WHO grades and is essential for tumor cell proliferation. in PLoS ONE 2012 (PubMed)

  3. Human Polyclonal KLF8 Primary Antibody for ELISA, WB - ABIN184763 : van Vliet, Turner, Crossley: Human Krüppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription. in Nucleic acids research 2000 (PubMed)

  4. Human Polyclonal KLF8 Primary Antibody for WB - ABIN2787477 : Wang, Zheng, Liu, Xia, McKeown-Longo, Hung, Zhao: Krüppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion. in Cancer research 2007 (PubMed)

More Antibodies against KLF8 Interaction Partners

Zebrafish Kruppel-Like Factor 8 (KLF8) interaction partners

  1. Results demonstrate a novel role of Klf8, achieved via modulation of p53 (show TP53 Antibodies) and met expression, in the maintenance neuronal progenitors and development of Purkinje cells and the proliferation of granule cells in the cerebella of zebrafish embryos

Human Kruppel-Like Factor 8 (KLF8) interaction partners

  1. Overexpression of KLF8 may contribute to the progression of pancreatic cancer, and downregulation of KLF8 expression by lentivirus-delivered shRNA is a novel therapeutic approach for PC.

  2. KLF8 plays a crucial role in proliferation and migration of bladder cancer cells

  3. KLF8-induced FHL2 (show FHL2 Antibodies) activation is a novel and critical signaling mechanism underlying human colorectal cancer invasion and metastasis.

  4. KLF8 and miR141/EGFR (show EGFR Antibodies) have roles in signaling pathway potentially crucial for breast cancer malignancy

  5. KLF8 suppression induced cell differentiation and inhibited tumorigenesis in colorectal cancer

  6. MiR (show MLXIP Antibodies)-135a inhibits migration and invasion and regulates epithelial-mesenchymal transition-related marker genes by targeting KLF8 in lung cancer cells.

  7. KLF8 is a novel epithelial to mesenchymal transition regulating transcription factor that involved in the progression of gastric cancer.

  8. In this review, we focus on the functions, roles, and regulatory networks of these five KLFs in HCC (show FAM126A Antibodies), summarize key pathways, and propose areas for further investigation

  9. A novel KLF8 to EPSTI1 to VCP (show vcp Antibodies) to NF-kappaB (show NFKB1 Antibodies) signaling mechanism potentially critical for breast cancer invasion and metastasis.

  10. KLF8 is involved in hypoxia-induced multidrug resistance through inhibiting apoptosis and increasing the drug release rate by directly regulating MDR1 (show TBC1D9 Antibodies) transcription.

Mouse (Murine) Kruppel-Like Factor 8 (KLF8) interaction partners

  1. Klf8 is highly expressed in various regions of the mouse brain and in particular in the neurons, where it was localized in the cell nuclei.

  2. KLF3 and KLF8 have overlapping roles in vivo and participate in the silencing of embryonic globin expression during development.

  3. KLF8 is a key component of the transcription factor network that controls terminal differentiation during adipogenesis.

  4. PARP-1 (show PARP1 Antibodies) as a novel KLF8-binding and -regulating protein and provided new insights into the mechanisms underlying the regulation of KLF8 nuclear localization, stability, and functions.

  5. These results identified the KLF8 activation domain located between residues 101-260 where the well-conserved Q118 and Q248 are essential for recruiting p300 (show NOTCH1 Antibodies) and PCAF (show KAT2B Antibodies) to activate target gene transcription.

  6. sumoylation of KLF8 negatively regulates its transcriptional activity and cellular functions

  7. Klf8 is repressed by Klf3 (show KLF3 Antibodies) and activated by Klf1 (show KLF1 Antibodies) in vivo.

  8. KLF8 has two N terminal regulatory regions, one surrounding S165 and K171 and the other being two tandem ZFs, which are critical for the regulation of KLF8 nuclear localization and its cellular functions

Pig (Porcine) Kruppel-Like Factor 8 (KLF8) interaction partners

  1. results demonstrate that KLF8 can participate in regulating expression of alternate forms of HuR (show ELAVL1 Antibodies) mRNA along with NF-kappaB (show NFKB1 Antibodies) and other factors, depending on cellular contexts

KLF8 Antigen Profile

Protein Summary

This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with KLF8

  • Kruppel-like factor 8 (KLF8) antibody
  • si:ch211-208m1.2 (si:ch211-208m1.2) antibody
  • Kruppel-like factor 8 (LOC100351857) antibody
  • Kruppel-like factor 8 (Klf8) antibody
  • A830097P10Rik antibody
  • BKLF3 antibody
  • klf8 antibody
  • Klf8-ps1 antibody
  • RGD1565831 antibody
  • ZNF74 antibody
  • ZNF741 antibody

Protein level used designations for KLF8

Krueppel-like factor 8 , kruppel-like factor 8 , Kruppel-like factor 8 , basic krueppel-like factor 3 , basic kruppel-like factor 3 , zinc finger protein 741 , Kruppel-like factor 8, pseudogene 1

GENE ID SPECIES
100051239 Equus caballus
562805 Danio rerio
100351857 Oryctolagus cuniculus
11279 Homo sapiens
245671 Mus musculus
302582 Rattus norvegicus
100154631 Sus scrofa
430697 Gallus gallus
525558 Bos taurus
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