Kruppel-Like Factor 12 (KLF12) ELISA Kits

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. Additionally we are shipping KLF12 Antibodies (58) and KLF12 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human KLF12 KLF12 11278 Q9Y4X4
Anti-Mouse KLF12 KLF12 16597 O35738
Anti-Rat KLF12 KLF12 306110  
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More ELISA Kits for KLF12 Interaction Partners

Human Kruppel-Like Factor 12 (KLF12) interaction partners

  1. Data indicate Kruppel-like factor 12 protein (KLF12) as a metastasis-suppressor gene whose loss of function is associated with anoikis resistance through control of the cell cycle.

  2. KLF12 promotes tumor growth by directly activating early growth response protein 1 (EGR1 (show EGR1 ELISA Kits)). The levels of KLF12 and EGR1 (show EGR1 ELISA Kits) correlate synergistically with a poor prognosis. These results indicate that KLF12 likely plays an important role in CRC (show CALR ELISA Kits) and could serve as a potential prognostic marker and therapeutic target.

  3. the overexpression of miR (show MLXIP ELISA Kits)-141 augments anoikis resistance in ovarian cancer cells by targeting and repressing the expression of KLF12, which, in turn, competes for binding sites in the survivin (show BIRC5 ELISA Kits) promoter with Sp1 (show PSG1 ELISA Kits). The subsequent increase in survivin (show BIRC5 ELISA Kits) then protects ovarian cancer cells against anoikis by blocking the intrinsic apoptotic activity.

  4. Data show Kruppel-like factor 12 (KLF12) impairs endometrial decidualization by transcriptionally repressing Nur77 (show NR4A1 ELISA Kits) protein, and Nur77 (show NR4A1 ELISA Kits) overexpression reverses the poor decidual response of endometrial stromal cells (hESCs) in recurrent implantation failure (RIF) patients.

  5. SLC29A1 (show SLC29A1 ELISA Kits) rs760370 and KLF12 rs9543524 SNPs are associated with treatment induced thrombocytopenia in chronic hepatitis C patients treated with PEGIFN2b/ribavirin/combination.

  6. our results supported that miR (show MLXIP ELISA Kits)-205 was a miR (show MLXIP ELISA Kits) specific to basal-like breast carcinoma (BLBC). which functioned as tumor suppressor gene through directly targeting and negatively regulating proto-oncogene (show RAB1A ELISA Kits) KLF12. miR (show MLXIP ELISA Kits)-205 dysregulation was involved in invasion and apoptosis. miR (show MLXIP ELISA Kits)-205 and KLF12 provided a potential diagnosis biomarker and therapeutic approach for BLBC.

  7. Overexpression of KLF12 is associated with gastric cancer.

  8. Elevated KLF12 expression was accompanied by decreased FOXO1 (show FOXO1 ELISA Kits) expression in the endometria of patients with repeated implantation failure.

  9. overexpression of KLF12 in endometrial stromal cells significantly repressed the expression and secretion of decidualization biomarker genes and their products decidual prolactin (show PRL ELISA Kits) and insulin-like growth factor binding protein-1 (show IGFBPI ELISA Kits)

  10. The KLF12 rs1324913 A allele homozygous genotype is a possible predictor of Rheumatoid Arthritis.

Mouse (Murine) Kruppel-Like Factor 12 (KLF12) interaction partners

  1. KLF12 is involved in the maturation processes of collecting ducts after birth, and UT-A1 (show SLC14A2 ELISA Kits) is a target gene of KLF12.

KLF12 Antigen Profile

Antigen Summary

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KLF12

  • Kruppel-like factor 12b (klf12b) antibody
  • Kruppel-like factor 12 (KLF12) antibody
  • Kruppel-like factor 12 (LOC100342041) antibody
  • Kruppel-like factor 12 (Klf12) antibody
  • Kruppel-like factor 12a (klf12a) antibody
  • 2700063E05Rik antibody
  • AI225908 antibody
  • AI315654 antibody
  • AP-2rep antibody
  • AP2REP antibody
  • B130052C06Rik antibody
  • D530033K05Rik antibody
  • fb02h07 antibody
  • klf12 antibody
  • wu:fb02h07 antibody
  • zgc:77286 antibody
  • zgc:171689 antibody

Protein level used designations for KLF12

Krueppel-like factor 12 , Kruppel-like factor 12 , AP-2 repressor , AP-2rep transcription factor , KLF12 zinc finger transcriptional repressor , transcriptional repressor AP-2rep

GENE ID SPECIES
100126139 Danio rerio
100140477 Bos taurus
100342041 Oryctolagus cuniculus
11278 Homo sapiens
100174955 Sus scrofa
16597 Mus musculus
306110 Rattus norvegicus
798629 Danio rerio
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