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Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. Additionally we are shipping KLF2 Kits (9) and KLF2 Proteins (6) and many more products for this protein.
Showing 10 out of 111 products:
Human Polyclonal KLF2 Primary Antibody for ELISA, ICC - ABIN4329122
Kim, Kwon, Hong, Kang, Jeong, Kang, Jeong, Ahn: Restoration of angiogenic capacity of diabetes-insulted mesenchymal stem cells by oxytocin. in BMC cell biology 2013
Show all 3 Pubmed References
Human Polyclonal KLF2 Primary Antibody for IF (p), IHC (p) - ABIN680473
Wang, Wang, Shen, Yin, Tang: Effects of artesunate and ursolic acid on hyperlipidemia and its complications in rabbit. in European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2013
Show all 2 Pubmed References
Human Monoclonal KLF2 Primary Antibody for ELISA, WB - ABIN523760
Richardson, Jadlowsky, Didigu, Doms, Riley: Kruppel-like factor 2 modulates CCR5 expression and susceptibility to HIV-1 infection. in Journal of immunology (Baltimore, Md. : 1950) 2012
Guinea Pig Polyclonal KLF2 Primary Antibody for ChIP, IHC - ABIN2777573
Saavedra, Patterson, West, Randell, Riches, Malcolm, Cool, Nick, Dinarello: Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways. in American journal of respiratory cell and molecular biology 2008
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Human Monoclonal KLF2 Primary Antibody for CyTOF, FACS - ABIN4900476
Seifert, Sellmann, Bloehdorn, Wein, Stilgenbauer, Dürig, Küppers: Cellular origin and pathophysiology of chronic lymphocytic leukemia. in The Journal of experimental medicine 2012
Human Polyclonal KLF2 Primary Antibody for IHC, IHC (p) - ABIN4329130
Ferraro, Mafalda Lopes da, Grimes, Lee, Ketteler, Kriston-Vizi, Cutler: Weibel-Palade body size modulates the adhesive activity of its von Willebrand Factor cargo in cultured endothelial cells. in Scientific reports 2016
Human Polyclonal KLF2 Primary Antibody for WB - ABIN1538992
Gan, Dang, Han, Ling, Duan, Liu, Xu: ERK5/HDAC5-mediated, resveratrol-, and pterostilbene-induced expression of MnSOD in human endothelial cells. in Molecular nutrition & food research 2015
Transcription factor Kruppel-like factor 2 (KLF2) of the zinc finger family of DNA-binding proteins has recently emerged as a major molecular switch that controls endothelial homeostasis.
The findings point to KLF2 as a new gene involved in heritable pulmonary arterial hypertension.
we provide evidence that the tumor-suppressive microRNA miR (show MLXIP Antibodies)-1825 controls KLF2 expression. Reporter gene analyses revealed that both microRNAs directly targeted the 3'-untranslated region of KLF2 messenger RNA. These data demonstrated that miR (show MLXIP Antibodies)-1825 expression in serum of human glioma was associated with tumorigenesis and miR (show MLXIP Antibodies)-1825 may be used as a biomarker for identification of the pathological grade of glioma.
Long noncoding RNA XIST acts as an oncogene (show RAB1A Antibodies) in non-small cell lung cancer by epigenetically repressing KLF2 expression.
lysine-specific demethylase (show MBD2 Antibodies)-1 is an important oncogene (show RAB1A Antibodies) in gastric cancer, and lysine-specific demethylase (show MBD2 Antibodies)-1-mediated epigenetic repression of KLF2 plays a critical role in gastric cancer development and progression.
KLF2 is shown to be downregulated in pancreatic ductal adenocarcinoma (PDAC) clinical samples and overexpression of KLF2 inhibits the growth, migration, and metastasis of PDAC cancer cells.
KLF2 expression was decreased in gastric cancer and negatively correlated with lymphatic metastasis. KLF2 overexpression inhibited cell proliferation and invasive potential and downregulated the protein expression of PCNA (show PCNA Antibodies), Bcl-2 (show BCL2 Antibodies) and MMP-9 (show MMP9 Antibodies) in GC cells. KLF2 overexpression reduced xenograft tumor growth.
our data highlight an important role for KLF2/c-myc (show MYC Antibodies) pathway in HCC (show FAM126A Antibodies) development and progression.
Authors show that KLF2 induces the expression of CRABP2 (show CRABP2 Antibodies) and RARgamma and inhibits the expression FABP5 (show FABP5 Antibodies) and PPARbeta (show PPARD Antibodies)/delta thereby shifting RA signaling from the pro-carcinogenic FABP5 (show FABP5 Antibodies)/PPARbeta (show PPARD Antibodies)/delta to the growth-suppressing CRABP2 (show CRABP2 Antibodies)/RAR (show RARA Antibodies) path.
MicroRNA-30 mediates anti-inflammatory effects of shear stress and KLF2 via repression of Ang2 (show ANGPT2 Antibodies).
miR (show MYLIP Antibodies)-92a coregulates KLF4 (show KLF4 Antibodies) and KLF2 expression in arterial endothelium and contributes to phenotype heterogeneity associated with regional atherosusceptibility and protection in vivo.
Mouse embryos deficient in Orai1 (show TMEM132A Antibodies), Klf2, or Klf4 (show KLF4 Antibodies) showed a significantly reduced lymphatic density and impaired lymphatic development.
this study shows that KLF2 governs the degree of dendritic cells activation and hence the intensity of proatherogenic T cell responses
A deficiency of KLF2 increased the expression of Notch ligand (show JAG2 Antibodies) Jagged2 (show JAG2 Antibodies) via hypoxia-inducible factor 1alpha (HIF-1alpha (show HIF1A Antibodies)), which led to Th2 amplification.
our data demonstrate a protective role of KLF2 against glomerular endothelial cell injury and progression of chronic kidney disease in the model of compensatory renal hypertrophy
Under steady-state conditions, KLF2-deficient NK cells alter their expression of homeostatic homing receptors and subsequently undergo apoptosis due to IL-15 (show IL15 Antibodies) starvation.
KLF2 knockdown markedly reduced expression of miR (show MLXIP Antibodies)-155 in macrophages and macrophage activation.
study therefore establishes the pivotal role of Klf2 and Tfcp2l1 (show TFCP2L1 Antibodies) in mediating ESC self-renewal promoted by Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.
endothelial-specific loss of Mekk3 (show MAP3K3 Antibodies), Klf2 or Klf4 (show KLF4 Antibodies) markedly prevents cerebral cavernous malformation lesion formation, reverses the increase in Rho activity, and rescues lethality
knockdown of Klf2 expression in endothelial cells induced more endothelial cell injury in early diabetic nephropathy
KLF2 and ERG (show ERG Antibodies) associate in a physical complex and the two proteins synergistically activate transcription of Flk1 (show KDR Antibodies).
Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1\; MIM 601974) and the selectin CD62L (SELL\; MIM 153240) (summary by Weinreich et al., 2009
Kruppel-like factor 2 (lung)
, Krueppel-like factor 2
, Kruppel-like factor LKLF
, lung Kruppel-like zinc finger transcription factor
, lung krueppel-like factor
, lung Kruppel-like factor