Kruppel-Like Factor 6 Proteins (KLF6)

KLF6 encodes a member of the Kruppel-like family of transcription factors. Additionally we are shipping KLF6 Antibodies (49) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KLF6 1316 Q99612
KLF6 23849  
KLF6 58954  
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Top KLF6 Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 10 to 12 Days
$229.85
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 4 Days
$522.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 15 to 16 Days
$300.00
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,744.50
Details
Yeast Bordetella pertussis His tag   50 μg Log in to see 8 to 11 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Bordetella pertussis His tag   50 μg Log in to see 11 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$510.36
Details

KLF6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced KLF6 Proteins

  1. Human KLF6 Protein expressed in Wheat germ - ABIN1308760 : Huang, Li, Guo: KLF6 induces apoptosis in prostate cancer cells through up-regulation of ATF3. in The Journal of biological chemistry 2008 (PubMed)

More Proteins for Kruppel-Like Factor 6 (KLF6) Interaction Partners

Human Kruppel-Like Factor 6 (KLF6) interaction partners

  1. study identifies a new mechanism by which KLF6 regulates NF-kappaB (show NFKB1 Proteins) signaling, and how this mechanism is circumvented in glioblastoma through KLF6 loss.

  2. our results established the significance of activating the KLF6-E2F1 (show E2F1 Proteins) axis in aggressive primary metastatic clear cell renal cell carcinoma (show MOK Proteins)

  3. KLF6 overexpression suppressed the xenograft tumor growth.

  4. KLF6 and KLF15 are targeted and suppressed in breast cancer cells by miR (show MLXIP Proteins)-4262.

  5. KLF6 acts as a tumor suppressor in CMM cells and miR (show MLXIP Proteins)-4262 promotes the proliferation of CMM cells through KLF6-mediated EGFR (show EGFR Proteins) inactivation and p21 (show CDKN1A Proteins) upregulation.

  6. These results suggest that KLF6 regulates MMP14 (show MMP14 Proteins) transcription and is a critical player of the gene expression network triggered during endothelial repair.

  7. KLF6 is a novel regulator of human villous trophoblast fusion.

  8. KLF6 overexpression partially phenocopied chaetocin treatment in DDLPS cells and induced phenotypic changes that were consistent with adipocytic differentiation, suggesting that the effects of increased H3K9me3 may be mediated through KLF6

  9. Study revealed that overexpression of miR (show MLXIP Proteins)-101 inhibited the proliferation, cell migration, invasion, and promoted apoptosis of glioblastoma stem cells by directly targeting KLF6

  10. Data show that MiR (show MLXIP Proteins)-1301 and miR (show MLXIP Proteins)-210 specifically target the tumor suppressive KLF6-FL isoform but not the oncogenic KLF6-SV1 isoform in hepatocellular carcinoma.

Mouse (Murine) Kruppel-Like Factor 6 (KLF6) interaction partners

  1. we identified novel transcriptional targets of KLF6 in HCC cells including VAV3, a known activator of the RAC1 small GTPase. Indeed, RAC1 activity is increased in KLF6-knockdown cells in a VAV3-dependent manner, and knockdown of either RAC1 or VAV3 impairs HCC cell migration. Together, our data demonstrate a novel function for KLF6 in constraining HCC dissemination through the regulation of a VAV3-RAC1 signaling axis.

  2. Klf6 as required for developmental central nervous system myelination.Klf6 promotes oligodendrocyte differentiation and viability.

  3. observations reveal that KLF6 repress BCL6 (show BCL6 Proteins) to enhance macrophage inflammatory gene expression and function.

  4. present studies on the cardiac function of KLF6 show a new mechanism whereby cardiomyocytes regulate cardiac fibrosis through transcriptional control of the extracellular matrix factor thrombospondin 4 (show THBS4 Proteins)

  5. downregulates expression and secretion of granulocyte macrophage colony-stimulating factor (show CSF2 Proteins)

  6. KLF6-dependent regulation of the cytochrome c (show CYCS Proteins) oxidase assembly gene is critical for maintaining mitochondrial function and preventing podocyte apoptosis.

  7. findings provide novel evidence highlighting KLF6 function in response to malignant transformation, suggesting the relevance of KLF6 in controlling cell proliferation and hindering tumorigenesis

  8. KLF6 is required for optimal LPS (show TLR4 Proteins)-induced pro-inflammatory gene expression, acting cooperatively with NF-kappaB (show NFKB1 Proteins)

  9. KLF6 is a novel regulator of hepatic glucose and lipid metabolism in fatty liver.

  10. ALK1 (show ACVRL1 Proteins) is upregulated in endothelial cells during vascular injury by a synergistic cooperative mechanism between KLF6 and specificity protein 1 (show SP1 Proteins).

Zebrafish Kruppel-Like Factor 6 (KLF6) interaction partners

  1. Klf6a promotes hematopoietic stem and progenitor cell maintenance through Ccl25b-Ccr7 (show CCR7 Proteins) chemokine (show CCL1 Proteins) signaling.

  2. In the spinal cord, klf7 (show KLF7 Proteins)- and klf6a-expressing cells are found in both the dorsal and ventral horns. Numerous sensory structures (e.g. auditory, lateral line, olfactory and visual) and several motor nuclei (e.g. oculomotor, trigeminal, and vagal motor nuclei) contain klf7 (show KLF7 Proteins)- and/or klf6a-expressing cells

  3. copeb/Klf6 is essential for the development of endoderm-derived organs

KLF6 Protein Profile

Protein Summary

This gene encodes a member of the Kruppel-like family of transcription factors. The zinc finger protein is a transcriptional activator, and functions as a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene, some of which are implicated in carcinogenesis.

Gene names and symbols associated with Kruppel-Like Factor 6 Proteins (KLF6)

  • Kruppel-like factor 6 (klf6-b)
  • Kruppel-like factor 6 (KLF6)
  • Krueppel-like factor 6 (klf6)
  • Kruppel-like factor 6 (LOC100227132)
  • krueppel-like factor 6 (klf6)
  • Kruppel-like factor 6 (Klf6)
  • Kruppel-like factor 6 (klf6-a)
  • Kruppel-like factor 6a (klf6a)
  • Aa1017 protein
  • AI448727 protein
  • BCD1 protein
  • C86813 protein
  • cb538 protein
  • CBA1 protein
  • Copeb protein
  • CPBP protein
  • FM2 protein
  • FM6 protein
  • GBF protein
  • Ierepo1 protein
  • Ierepo3 protein
  • klf6 protein
  • MGC53475 protein
  • MGC127307 protein
  • PAC1 protein
  • R75280 protein
  • ST12 protein
  • wu:fb76d04 protein
  • wu:fb92h03 protein
  • wu:fe26g06 protein
  • wu:fk78f12 protein
  • Zf9 protein

Protein level used designations for Kruppel-Like Factor 6 Proteins (KLF6)

Kruppel-like factor 6 , core promoter element binding protein , Krueppel-like factor 6 , krueppel-like factor 6 , B-cell-derived protein 1 , GC-rich binding factor , GC-rich sites-binding factor GBF , Kruppel-like zinc finger protein Zf9 , core promoter element-binding protein , proto-oncogene BCD1 , protooncogene B-cell derived 1 , suppression of tumorigenicity 12 (prostate) , suppressor of tumorigenicity 12 protein , transcription factor Zf9 , immediate early response, erythropoietin 1

GENE ID SPECIES
379949 Xenopus laevis
505884 Bos taurus
100196412 Salmo salar
100227132 Taeniopygia guttata
100528149 Ictalurus punctatus
1316 Homo sapiens
100174961 Sus scrofa
23849 Mus musculus
58954 Rattus norvegicus
446965 Xenopus laevis
420463 Gallus gallus
280650 Danio rerio
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