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anti-L(3)mbt-Like 1 (Drosophila) (L3MBTL1) Antibodies

L3MBTL1 represents a polycomb group gene. Additionally we are shipping L3MBTL1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
L3MBTL1 241764 A2A5N8
L3MBTL1 26013 Q9Y468
L3MBTL1 311613 D3ZWK4
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Top anti-L3MBTL1 Antibodies at

Showing 10 out of 34 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated WB WB Suggested Anti-L3MBTL Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
Mouse Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB L3MBTL1 antibody tested by Western blot. Nuclear extract of HeLa cells (20 µg) was probed with L3MBTL1 antibody (1:2,000 dilution). 200 μL Log in to see 1 to 2 Days
Human Rabbit Un-conjugated ICC, IF, WB WB Image L3MBTL antibody detects L3MBTL protein by Western blot analysis. A. 30 µg 293T whole cell lysate/extract B. 30 µg whole cell lysate/extract of human L3MBTL-transfected 293T cells 7.5 % SDS-PAGE L3MBTL antibody , dilution: 1:5000 WB Image Sample(30 ug whole cell lysate) A:HeLa S3, 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ICC, IF, WB 100 μL Log in to see 8 to 10 Days
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
Human Rabbit Un-conjugated IP, WB 25 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days

L3MBTL1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) ,

Human , , ,

Rat (Rattus)

Top referenced anti-L3MBTL1 Antibodies

  1. Human Polyclonal L3MBTL1 Primary Antibody for WB - ABIN2668237 : Qin, Van Buren, Huang, Zhong, Mostoslavsky, Akbarian, Hock: Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice. in The Journal of biological chemistry 2010 (PubMed)

  2. Cow (Bovine) Polyclonal L3MBTL1 Primary Antibody for WB - ABIN2776522 : Min, Allali-Hassani, Nady, Qi, Ouyang, Liu, MacKenzie, Vedadi, Arrowsmith: L3MBTL1 recognition of mono- and dimethylated histones. in Nature structural & molecular biology 2007 (PubMed)

More Antibodies against L3MBTL1 Interaction Partners

Mouse (Murine) L(3)mbt-Like 1 (Drosophila) (L3MBTL1) interaction partners

  1. L3mbtl1 loss-of-function was associated with significant decreases in depression and and anxiety in some of the behavioral paradigms.

  2. generation and analysis of mice after disruption of L3MBTL1

Human L(3)mbt-Like 1 (Drosophila) (L3MBTL1) interaction partners

  1. The polycomb group protein L3MBTL1 represses a SMAD5 (show SMAD5 Antibodies)-mediated hematopoietic transcriptional program in human pluripotent stem cells.

  2. High expression of L3MBTL1 was associated with low grade and hormone receptor (show NR4A1 Antibodies)-positive tumors, as well as low risk of disease recurrence and breast cancer death.

  3. depletion of L3MBTL1 does not affect hESC self-renewal, rather it enhances differentiation toward extra-embryonic trophoblast tissues

  4. Data suggest that the loss of L3MBTL1 contributes to the development of 20q(-) hematopoietic malignancies by inducing replicative stress, DNA damage, and genomic instability.

  5. SET8 (show SETD8 Antibodies)-mediated methylation of p53 (show TP53 Antibodies) at Lys (show LYZ Antibodies)-382 promotes the interaction between L3MBTL1 and p53 (show TP53 Antibodies) in cells.

  6. haploinsufficiency of L3MBTL1 contributes to some (20q-) myeloproliferative neoplasms, especially polycythemia vera (show IGF2BP3 Antibodies), by promoting erythroid differentiation

  7. The ability of TEL (show ETV6 Antibodies) to repress TEL (show ETV6 Antibodies)-responsive promoters is enhanced by the presence of H-L(3)MBT, an effect dependent on the H-L(3)MBT and the TEL (show ETV6 Antibodies) interacting domains, which are mapped to their respective SPM (show NPC1 Antibodies)/SAM (show TTN Antibodies) domains.

  8. represents a previously undescribed imprinted locus, a vertebrate Polycomb (show CBX2 Antibodies) group gene shown to be regulated by this mechanism, and has implications for the pathogenesis of myeloid malignancies associated with 20q deletions

  9. L3MBTL may have a role in myeloid leukemia (show BCL11A Antibodies)

  10. The MBT domain is related to protein domains that directly bind methylated histone residues and study found that L3MBTL1 MBT domains compact nucleosomal arrays dependent on mono- and dimethylation of histone H4 lysine 20 and of histone H1b lysine 26.

L3MBTL1 Antigen Profile

Protein Summary

This gene represents a polycomb group gene. The encoded protein functions to regulate gene activity, likely via chromatin modification. The encoded protein may also be necessary for mitosis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with L3MBTL1

  • l(3)mbt-like (Drosophila) (L3mbtl1) antibody
  • l(3)mbt-like 1 (Drosophila) (L3MBTL1) antibody
  • l(3)mbt-like 1 (Drosophila) (L3mbtl1) antibody
  • C630004G01 antibody
  • dJ138B7.3 antibody
  • H-L(3)MBT antibody
  • L3MBTL antibody
  • mKIAA0681 antibody
  • RGD1307316 antibody
  • ZC2HC3 antibody

Protein level used designations for L3MBTL1

H-l(3)mbt protein , L(3)mbt protein homolog , lethal(3)malignant brain tumor-like protein 1 , l(3)mbt protein homolog , lethal (3) malignant brain tumor l(3) , L(3)malignant brain tumor-like protein

241764 Mus musculus
26013 Homo sapiens
529298 Bos taurus
419115 Gallus gallus
311613 Rattus norvegicus
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