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L(3)mbt-Like 1 (Drosophila) (L3MBTL1) ELISA Kits

L3MBTL1 represents a polycomb group gene. Additionally we are shipping L3MBTL1 Antibodies (34) and L3MBTL1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse L3MBTL1 L3MBTL1 241764 A2A5N8
Anti-Human L3MBTL1 L3MBTL1 26013 Q9Y468
Anti-Rat L3MBTL1 L3MBTL1 311613 D3ZWK4
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More ELISA Kits for L3MBTL1 Interaction Partners

Mouse (Murine) L(3)mbt-Like 1 (Drosophila) (L3MBTL1) interaction partners

  1. L3mbtl1 loss-of-function was associated with significant decreases in depression and and anxiety in some of the behavioral paradigms.

  2. generation and analysis of mice after disruption of L3MBTL1

Human L(3)mbt-Like 1 (Drosophila) (L3MBTL1) interaction partners

  1. The polycomb group protein L3MBTL1 represses a SMAD5 (show SMAD5 ELISA Kits)-mediated hematopoietic transcriptional program in human pluripotent stem cells.

  2. High expression of L3MBTL1 was associated with low grade and hormone receptor (show NR4A1 ELISA Kits)-positive tumors, as well as low risk of disease recurrence and breast cancer death.

  3. depletion of L3MBTL1 does not affect hESC self-renewal, rather it enhances differentiation toward extra-embryonic trophoblast tissues

  4. Data suggest that the loss of L3MBTL1 contributes to the development of 20q(-) hematopoietic malignancies by inducing replicative stress, DNA damage, and genomic instability.

  5. SET8 (show SETD8 ELISA Kits)-mediated methylation of p53 (show TP53 ELISA Kits) at Lys (show LYZ ELISA Kits)-382 promotes the interaction between L3MBTL1 and p53 (show TP53 ELISA Kits) in cells.

  6. haploinsufficiency of L3MBTL1 contributes to some (20q-) myeloproliferative neoplasms, especially polycythemia vera (show IGF2BP3 ELISA Kits), by promoting erythroid differentiation

  7. The ability of TEL (show ETV6 ELISA Kits) to repress TEL (show ETV6 ELISA Kits)-responsive promoters is enhanced by the presence of H-L(3)MBT, an effect dependent on the H-L(3)MBT and the TEL (show ETV6 ELISA Kits) interacting domains, which are mapped to their respective SPM (show NPC1 ELISA Kits)/SAM (show TTN ELISA Kits) domains.

  8. represents a previously undescribed imprinted locus, a vertebrate Polycomb (show CBX2 ELISA Kits) group gene shown to be regulated by this mechanism, and has implications for the pathogenesis of myeloid malignancies associated with 20q deletions

  9. L3MBTL may have a role in myeloid leukemia (show BCL11A ELISA Kits)

  10. The MBT domain is related to protein domains that directly bind methylated histone residues and study found that L3MBTL1 MBT domains compact nucleosomal arrays dependent on mono- and dimethylation of histone H4 lysine 20 and of histone H1b lysine 26.

L3MBTL1 Antigen Profile

Antigen Summary

This gene represents a polycomb group gene. The encoded protein functions to regulate gene activity, likely via chromatin modification. The encoded protein may also be necessary for mitosis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with L3MBTL1

  • l(3)mbt-like (Drosophila) (L3mbtl1) antibody
  • l(3)mbt-like 1 (Drosophila) (L3MBTL1) antibody
  • l(3)mbt-like 1 (Drosophila) (L3mbtl1) antibody
  • C630004G01 antibody
  • dJ138B7.3 antibody
  • H-L(3)MBT antibody
  • L3MBTL antibody
  • mKIAA0681 antibody
  • RGD1307316 antibody
  • ZC2HC3 antibody

Protein level used designations for L3MBTL1

H-l(3)mbt protein , L(3)mbt protein homolog , lethal(3)malignant brain tumor-like protein 1 , l(3)mbt protein homolog , lethal (3) malignant brain tumor l(3) , L(3)malignant brain tumor-like protein

241764 Mus musculus
26013 Homo sapiens
529298 Bos taurus
419115 Gallus gallus
311613 Rattus norvegicus
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