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Putative Polycomb group (PcG) protein. Additionally we are shipping L(3)mbt-Like 3 (Drosophila) Antibodies (42) and many more products for this protein.
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RBPJ (show RBPJ Proteins) interacts with L3MBTL3 to promote repression of Notch (show NOTCH1 Proteins) signaling via histone demethylase (show MBD2 Proteins) KDM1A (show KDM1A Proteins).
Mutation in L3MBTL3 gene is associated with insulin (show INS Proteins)-resistant cardiometabolic disease.
These observations are consistent with the hypothesis that L3MBTL3 engages methylated histone tails as a dimer while carrying out its normal function and provides an explanation for the presence of repeated MBT (show PRTN3 Proteins) domains within L3MBTL3.
The mouse MBT-1 protein influences myelopoiesis by transiently enhancing p57(KIP2 (show CDKN1C Proteins)) expression levels.
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity). Required for normal maturation of myeloid progenitor cells.
H-l(3)mbt-like protein 3
, l(3)mbt-like protein 3
, lethal(3)malignant brain tumor-like protein 3