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Putative Polycomb group (PcG) protein. Additionally we are shipping L3MBTL2 Proteins (6) and many more products for this protein.
Showing 10 out of 45 products:
Cow (Bovine) Polyclonal L3MBTL2 Primary Antibody for WB - ABIN2778379
Collins, Wright, Edwards, Davis, Grinham, Cole, Goward, Aguado, Mallya, Mokrab, Huckle, Beare, Dunham: A genome annotation-driven approach to cloning the human ORFeome. in Genome biology 2004
Human Polyclonal L3MBTL2 Primary Antibody for WB - ABIN4889662
LaFave, Béguelin, Koche, Teater, Spitzer, Chramiec, Papalexi, Keller, Hricik, Konstantinoff, Micol, Durham, Knutson, Campbell, Blum, Shi, Doud, Krivtsov, Chung, Khodos, de Stanchina, Ouerfelli et al.: Loss of BAP1 function leads to EZH2-dependent transformation. ... in Nature medicine 2015
L3MBTL2 polymorphism is associated with neuroticism.
Our findings highlight a PcG/L3MBTL2 collaboration that attains repressive chromatin without entailing histone lysine methylation marks.
High-resolution crystallographic analysis of the four MBT (show PRTN3 Antibodies) repeats of L3MBTL2 reveals its unique asymmetric rhomboid architecture, as well as binding mechanism, which preclude the interaction of the first three MBT (show PRTN3 Antibodies) repeats with methylated peptides.
determination of the solution structure of the FCS zinc finger of L3MBTL2; structure consists of a beta (show SUCLA2 Antibodies)-hairpin followed by an alpha-helix; structure is consistent with the proposal that FCS zinc fingers bind to regulatory RNAs
Disruption of L3mbtl2 results in embryonic lethality with failure of gastrulation.
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27' (By similarity).
lethal(3)malignant brain tumor-like protein 2
, l(3)mbt-like 2 (Drosophila)
, L(3)mbt-like 2 protein
, Lethal(3)malignant brain tumor-like 2 protein
, l(3)mbt-like protein 2
, lethal(3)malignant brain tumor-like protein 2-like
, H-l(3)mbt-like protein 2
, L(3)mbt-like protein 2
, l(3)mbt-like 2 protein
, lethal(3)malignant brain tumor-like 2 protein