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LAG1 Homolog, Ceramide Synthase 5 Proteins (LASS5)

May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. Additionally we are shipping LAG1 Homolog, Ceramide Synthase 5 Antibodies (61) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LASS5 91012 Q8N5B7
LASS5 71949 Q9D6K9
Rat LASS5 LASS5 366984  
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Top LAG1 Homolog, Ceramide Synthase 5 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
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Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
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HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
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LASS5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for LAG1 Homolog, Ceramide Synthase 5 (LASS5) Interaction Partners

Human LAG1 Homolog, Ceramide Synthase 5 (LASS5) interaction partners

  1. mRNA level of CerS5 is higher in cancerous cell lines and decreases following the induction of apoptosis.

  2. Overexpression of CerS5 increased apoptosis in HeLa cells.

  3. study identifies LASS5 as a genuine dihydroceramide synthase and demonstrates that mammalian dihydroceramide synthases do not require additional subunits for their activity

  4. accumulation of C(16)-ceramide in mitochondria formed from the protein kinase C-dependent salvage pathway results at least in part from the action of longevity-assurance homologue 5, and the generated ceramide modulates the p38 (show CRK Proteins) cascade via PP1 (show PPA1 Proteins)

  5. Down-regulation of either acid sphingomyelinase (show SMPD1 Proteins) or LASS 5-attenuated ceramide accumulation and H/R-induced Bax (show BAX Proteins) translocation to mitochondria.

Mouse (Murine) LAG1 Homolog, Ceramide Synthase 5 (LASS5) interaction partners

  1. Ceramide synthase 5 is essential to maintain C16:0-ceramide pools and contributes to the development of diet-induced obesity.

  2. Transfection of Lass5 cDNA into or pulse of Lass5 peptide onto B7-1 (show CD80 Proteins) positive RMA-S cells overcomes the requirement of the B7-1 (show CD80 Proteins)/CD28 (show CD28 Proteins) signal for T effector response.

  3. Data indicate that oxidized phospholipids (OxPLs)-induced ceramide synthases (CerS1 (show CERS1 Proteins)-Cers6 (show CERS6 Proteins)) activity in macrophages is responsible for the accumulation of ceramide.

  4. Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes.

  5. Lag1p family members trh1 (show CERS4 Proteins) and trh4 regulate (dihydro)ceramide synthases responsible for production of sphingolipids containing different fatty acids

  6. LASS5 is the major ceramide synthase gene product involved in sphingolipid production that may also regulate phosphatidylcholine (show SGMS2 Proteins) metabolism in pulmonary epithelia

LAG1 Homolog, Ceramide Synthase 5 (LASS5) Protein Profile

Protein Summary

May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner (By similarity).

Gene names and symbols associated with LASS5

  • ceramide synthase 5 (LASS5)
  • ceramide synthase 5 (cers5)
  • ceramide synthase 5 (CERS5)
  • LAG1 homolog, ceramide synthase 5 (LASS5)
  • ceramide synthase 5 (Cers5)
  • 2310081H14Rik protein
  • AU045339 protein
  • AW544927 protein
  • Lass5 protein
  • Trh4 protein

Protein level used designations for LASS5

LAG1 homolog, ceramide synthase 5 , LAG1 longevity assurance homolog 5-like , LAG1 longevity assurance homolog 5 , TRAM homolog 4 , longevity assurance homolog 5 , translocating chain-associating membrane protein homolog 4

GENE ID SPECIES
100059999 Equus caballus
451891 Pan troglodytes
713449 Macaca mulatta
100101657 Xenopus (Silurana) tropicalis
100231332 Taeniopygia guttata
100400191 Callithrix jacchus
100454836 Pongo abelii
530776 Bos taurus
495501 Xenopus laevis
91012 Homo sapiens
71949 Mus musculus
366984 Rattus norvegicus
426879 Gallus gallus
477611 Canis lupus familiaris
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