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LMO7 encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. Additionally we are shipping LMO7 Antibodies (30) and and many more products for this protein.
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lmo7(-/-) mice had no abnormalities in skeletal muscle morphology, physiological function, or regeneration. Lmo7 is dispensable for skeletal muscle and cardiac physiology and pathophysiology.
This study demonstrated that loss of Lmo7 in mice causes myopathic phenotypes similar to those seen in other EDMD (show EMD ELISA Kits) mouse models.
Increased susceptibility to spontaneous lung cancer in mice lacking LIM-domain only 7 is reported.
reveal the temporal and spatial expression patterns of this important gene during mouse, chicken and fish development and our findings suggest essential functions for LMO7 during vertebrate heart development
Data suggest that Lmo7 is localized at the perinuclear region and in fibril-like structures along subsarcolemma of human skeletal myoblasts whereas in human myotubes Lmo7 is found diffuse throughout the cytoplasm.
show that LMO7 is upregulated in the stroma of invasive breast carcinoma in a manner that correlates with the increased expression of serum response factor target genes
functional interaction between emerin (show EMD ELISA Kits) and Lmo7 is crucial for temporally regulating the expression of key myogenic differentiation genes.
Lmo7 positively regulates many EDMD (show EMD ELISA Kits)-relevant genes (including emerin (show EMD ELISA Kits)), and is feedback-regulated by binding to emerin (show EMD ELISA Kits).
This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, however, the full-length nature of some variants is not known.
LIM domain only 7
, LIM domain only protein 7
, TGF-beta induced protein
, LIM domain 7
, F-box only protein 20
, F-box protein Fbx20
, LIM domain only 7 protein
, zinc-finger domain-containing protein