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anti-LIM Domain Binding 1 (LDB1) Antibodies

Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. Additionally we are shipping LIM Domain Binding 1 Protein Proteins (6) and LIM Domain Binding 1 Protein Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LDB1 16825 P70662
LDB1 8861 Q86U70
LDB1 309447  
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Top anti-LIM Domain Binding 1 Protein Antibodies at antibodies-online.com

Showing 10 out of 74 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-LDB1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-LDB1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of LDB1 Antibody (C-term) in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the LDB1 antibody detected the LDB1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB LDB1 Antibody (C-term) (ABIN658786) western blot analysis in ZR-75-1 cell line lysates (35 µg/lane). This demonstrates the LDB1 antibody detected the LDB1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), WB IHC-P Image LDB1 antibody [N2C3] detects LDB1 protein at nucleus on rat middle brain by immunohistochemical analysis. Sample: Paraffin-embedded rat middle brain. LDB1 antibody [N2C3] , dilution: 1:500. IHC-P Image Immunohistochemical analysis of paraffin-embedded U87 Xenograft, using LDB1, antibody at 1:100 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated ELISA, WB Western blot using affinity purified anti-LDB1 antibody shows detection of LDB1 protein (arrowhead) in Jurkat whole cell lysate.   Approximately 30 µg of lysate was loaded prior to separation and transfer to nitrocellulose.  Primary antibody was used at a 1:1,800 dilution in 5% BLOTTO in PBS reacted overnight at 4°C.  The membrane was washed and reacted with a 1:20,000 dilution of DyLight™800 conjugated Gt-a-Rabbit IgG [H&L] MX (611-145-122) for 45 min at room temperature (800 nm channel, green).   Molecular weight estimation was made by comparison to prestained MW markers in lane M (700 nm channel, red).   Fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc.  Other detection systems will yield similar results. 100 μg Log in to see 2 to 3 Days
$369.00
Details
Chicken Rabbit Un-conjugated EIA   0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Spleen (formalin-fixed, paraffin-embedded) stained with LDB1 antibody ABIN214791 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Prostate (formalin-fixed, paraffin-embedded) stained with LDB1 antibody ABIN214791 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Dog Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

LDB1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-LIM Domain Binding 1 Protein Antibodies

  1. Chicken Polyclonal LIM Domain Binding 1 Protein Primary Antibody for EIA - ABIN118013 : Visvader, Mao, Fujiwara, Hahm, Orkin: The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Show all 7 references for ABIN118013

  2. Human Polyclonal LIM Domain Binding 1 Protein Primary Antibody for EIA, WB - ABIN953152 : Howard, Ransom, Maurer: Transcription intermediary factor 1gamma decreases protein expression of the transcriptional cofactor, LIM-domain-binding 1. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 5 references for ABIN953152

  3. Chicken Polyclonal LIM Domain Binding 1 Protein Primary Antibody for WB - ABIN2780230 : Marini, Bongers, Cusano, Di Duca, Seri, Knoers, Ravazzolo: Confirmation of CLIM2/LMX1B interaction by yeast two-hybrid screening and analysis of its involvement in nail-patella syndrome. in International journal of molecular medicine 2003 (PubMed)

More Antibodies against LIM Domain Binding 1 Protein Interaction Partners

Xenopus laevis LIM Domain Binding 1 (LDB1) interaction partners

  1. The functional cloning, expression pattern, overexpression, and knockdown data show that an ldb1-regulated mechanism acts as an early signal for Xenopus lens induction.

Mouse (Murine) LIM Domain Binding 1 (LDB1) interaction partners

  1. SSBP3 (show SSBP3 Antibodies) Interacts With Islet-1 (show ISL1 Antibodies) and Ldb1 to Impact Pancreatic beta-Cell Target Genes

  2. the Isl1 (show ISL1 Antibodies)/Ldb1 complex orchestrates a network for heart-specific transcriptional regulation and coordination in three-dimensional space during cardiogenesis.

  3. results indicate that LDB1-dependent looping events can deliver repressive cargo to cognate promoters to mediate promoter pausing events in a pituitary cell type

  4. Expression pattern of Isl1 (show ISL1 Antibodies) and its co-factor Ldb1, were analyzed in small intestine.

  5. Data suggest that the function of LIM domain binding protein 1 (LDB1) in the neural crest-derived palatal mesenchyme is essential for normal morphogenesis of the secondary palate.

  6. the LDB1 dimerization domain (DD) is necessary and, when fused to LMO2 (show LMO2 Antibodies), sufficient to completely restore LCR-promoter looping and transcription in LDB1-depleted cells

  7. Ldb1 plays an essential role as a transcription co-regulator of Lhx6 (show LHX6 Antibodies) and Lhx8 (show LHX8 Antibodies) in the control of mammalian telencephalon development.

  8. These results provide a foundation for defining the mechanism and scope of Ldb1 complex activity during erythropoiesis.

  9. Data indicte that the regulation of essential developmental factors by Ldb1 defines it as an upstream transcriptional regulator of hematopoietic/endothelial development.

  10. Isl1 (show ISL1 Antibodies) and the Ldb co-regulators of transcription are essential early determinants of mouse limb development

Human LIM Domain Binding 1 (LDB1) interaction partners

  1. SSBP3 (show SSBP3 Antibodies) Interacts With Islet-1 (show ISL1 Antibodies) and Ldb1 to Impact Pancreatic beta-Cell Target Genes

  2. Alanine scanning mutagenesis of the LIM (show PDLIM5 Antibodies) interaction domain of LDB1 revealed a discrete motif, R(320)LITR, required for LMO2 (show LMO2 Antibodies) binding.

  3. Clim2, in a complex with LMO4 (show LMO4 Antibodies), supports mammary stem cells by directly targeting the Fgfr2 (show FGFR2 Antibodies) promoter in basal cells to increase its expression

  4. In t(8;21) leukemia cells, LDB1 functions as a component of the stable AML1 (show RUNX1 Antibodies)-ETO (show RUNX1T1 Antibodies)-containing transcription factor complex (AETFC). The AETFC components cooperatively regulate gene expression and contribute to leukemogenesis.

  5. We investigated NLI (Ldb1 homolog) complex occupancy and chromatin conformation of the beta-globin (show HBB Antibodies) locus in human erythroid cells.

  6. These studies are consistent with a model in which TIF1gamma (show TRIM33 Antibodies) acts to ubiquitinate LDB1 leading to degradation of LDB1 and changes in transcription of LDB1-dependent promoters.

  7. Expression of LDB1 (LIM-domain-binding 1) protein in which Lys134 is replaced with arginine leads to enhanced expression of the mutant protein compared with the wild-type protein.

  8. 1H, 15N and 13C assignments of FLIN4, an intramolecular LMO4 (show LMO4 Antibodies):ldb1 complex

  9. Ssdp (show SSBP3 Antibodies) proteins interact with the LIM (show PDLIM5 Antibodies)-domain-binding protein Ldb1 to regulate development

  10. characterize the assembly of a five-component complex containing TAL1 (show TAL1 Antibodies), LMO2 (show LMO2 Antibodies), Ldb1, E12 (show ELSPBP1 Antibodies), and DNA. The bHLH domains of TAL1 (show TAL1 Antibodies) and E12 (show ELSPBP1 Antibodies) alone primarily formed helical homodimers, but together formed heterodimers, to which LMO2 (show LMO2 Antibodies) bound with high affinity

Zebrafish LIM Domain Binding 1 (LDB1) interaction partners

  1. Centrosome movements in vivo correlate with specific neurite formation downstream of LIM homeodomain transcription factor activity.

  2. Study identifies a number of novel Ldb1 interacting proteins in murine erythroleukaemic cells, namely Eto-2 (show CBFA2T3 Antibodies), the cyclin-dependent kinase (show CDK1 Antibodies) Cdk9 (show CDK9 Antibodies), Lmo4 (show LMO4 Antibodies); morphilino-mediated knockdowns in zebrafish show these factors to be essential for haematopoiesis.

LIM Domain Binding 1 Protein (LDB1) Antigen Profile

Protein Summary

Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors.

Gene names and symbols associated with LDB1

  • LIM domain binding 1 (ldb1) antibody
  • LIM domain binding 1 (Ldb1) antibody
  • LIM domain binding 1 (LDB1) antibody
  • LIM domain binding protein 1 (xldb1) antibody
  • LIM-domain binding factor 1b (ldb1b) antibody
  • chi antibody
  • CLIM2 antibody
  • ldb1 antibody
  • NLI antibody
  • xldb1 antibody

Protein level used designations for LDB1

CLIM-2 , LDB-1 , LIM domain-binding factor CLIM2 , LIM domain-binding protein 1 , carboxyl-terminal LIM domain-binding protein 2 , mLdb1 , nuclear LIM interactor , cLdb1 , neural Src-interacting protein , neural src interacting protein , LIM domain-binding factor-1 , carboxy terminal LIM domain protein 2 , hLdb1 , LIM-domain binding factor 1

GENE ID SPECIES
380241 Xenopus laevis
16825 Mus musculus
395952 Gallus gallus
8861 Homo sapiens
477804 Canis lupus familiaris
309447 Rattus norvegicus
779363 Xenopus laevis
30576 Danio rerio
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