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LIM Domain Only 1 (Rhombotin 1) Proteins (LMO1)

This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. Additionally we are shipping LMO1 Antibodies (35) and LMO1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LMO1 109594 Q924W9
Rat LMO1 LMO1 245979  
LMO1 4004 P25800
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Top LMO1 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 9 to 11 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,346.67
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,348.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,348.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details

LMO1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

Top referenced LMO1 Proteins

  1. Human LMO1 Protein expressed in Escherichia coli (E. coli) - ABIN1047610 : McGuire, Hockett, Pollock, Bartholdi, OBrien, Korsmeyer: The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein. in Molecular and cellular biology 1989 (PubMed)
    Show all 4 references for ABIN1047610

More Proteins for LIM Domain Only 1 (Rhombotin 1) (LMO1) Interaction Partners

Mouse (Murine) LIM Domain Only 1 (Rhombotin 1) (LMO1) interaction partners

  1. SCL (show TAL1 Proteins)-LMO1 upregulated a stem cell gene signature in DN3 thymocytes.

  2. Loss of Lmo1 repression may be one of the causes accounting for the phenotypic differences identified between the Arx((GCG)7)and Arx(432-455dup24) mouse models.

  3. SCL (show TAL1 Proteins), LMO1, and Notch1 (show NOTCH1 Proteins) gain of function, together with an active pre-T-cell antigen receptor (show PTCRA Proteins), might represent the minimum set of complementing events for the transformation of susceptible thymocytes into cancer cells

  4. Results suggest that all four members of the LIM (show PDLIM5 Proteins)-only family -- LMO1, 2, 3, and 4 -- are important regulators of distinct developmental pathways.

  5. Lmo1 takes part in a Hox (show MSH2 Proteins) paralogue 2-dependent network regulating anteroposterior and dorsoventral hindbrain patterning

Human LIM Domain Only 1 (Rhombotin 1) (LMO1) interaction partners

  1. LMO1 appears to be a coactivator of AR involved in the progression of prostate cancer

  2. data suggest that genetic variants in LMO1 are associated with increased NB risk in Chinese children.

  3. a polymorphism within a super-enhancer element in the first intron of LMO1 influences neuroblastoma (show ARHGEF16 Proteins) susceptibility through differential GATA (show QRSL1 Proteins) transcription factor binding and direct modulation of LMO1 expression in cis (show CISH Proteins)

  4. LMO1 is a commonly activated tumor promoter that activates AKT (show AKT1 Proteins) signaling in non-small cell lung cancer.

  5. LMO1 is a commonly activated tumor promoter that activates AKT (show AKT1 Proteins) signaling in colorectal cancer and a new predictive marker for targeted therapy.

  6. results show that LMO1 is poised for expression in normal progenitors, where activation of SCL/TAL1 (show TAL1 Proteins) together with a breakdown of epigenetic repression of LMO1 regulatory elements

  7. genetic variants within LMO1 are associated with acute lymphoblastic leukemia and identify this gene as a strong candidate for precursor B-cell leukemogenesis.

  8. data show that common polymorphisms at the LMO1 locus are strongly associated with susceptibility to developing neuroblastoma (show ARHGEF16 Proteins), but also may influence the likelihood of further somatic alterations at this locus, leading to malignant progression

  9. 60% of transgenic mice that overexpressed both OLIG2 (show OLIG2 Proteins) and LMO1 developed pre-T lymphoblastic lymphoma/leukemia with large thymic tumor masses.

  10. The present data suggest that TGF-beta (show TGFB1 Proteins), LMO1, possibly RUNX3 (show RUNX3 Proteins), and GSDM (show GSDMA Proteins) form a regulatory pathway for directing the pit (show IRF6 Proteins) cells to apoptosis.

LMO1 Protein Profile

Protein Summary

This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions\; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with LMO1

  • LIM domain only 1 (rhombotin 1) (LMO1)
  • Rhombotin-1 (rbtn1)
  • LIM domain only 1 (Lmo1)
  • LIM domain only 1 (lmo1)
  • rhombotin-1 (lmo1)
  • cb524 protein
  • Dat1 protein
  • LMO1 protein
  • Lmo3 protein
  • Rbtn-1 protein
  • RBTN1 protein
  • RHOM1 protein
  • TTG1 protein
  • wu:fb76g02 protein
  • zgc:109794 protein

Protein level used designations for LMO1

LIM domain only 1 (rhombotin 1) , Rhombotin-1 , LIM domain only protein 1 , LIM only 1 , LMO-1 , T-cell translocation protein 1 , cysteine-rich protein TTG-1 , rhombotin-1 , etID41074.7 , lmo1b , LIM domain only protein 3 , LMO-3 , LIM domain only 3 , neuronal-specific transcription factor DAT1 , dopamine-inducible LIM-domain transcription factor DAT1 , T-cell translocation gene 1 , rhombotin 1

GENE ID SPECIES
749084 Pan troglodytes
100286459 Salmo salar
109594 Mus musculus
280646 Danio rerio
245979 Rattus norvegicus
4004 Homo sapiens
527152 Bos taurus
734798 Xenopus laevis
Selected quality suppliers for LMO1 Proteins (LMO1)
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