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LMO4 encodes a cysteine-rich protein that contains two LIM domains but lacks a DNA-binding homeodomain. Additionally we are shipping LIM Domain Only 4 Antibodies (70) and LIM Domain Only 4 Proteins (6) and many more products for this protein.
Lmo4 participates in the regulation of lung epithelial cell proliferation but is not essential for tumor progression.
LMO4 appears to form a hub in protein-protein interaction networks, linking numerous pathways within cells.
Clim2 (show LDB1 ELISA Kits), in a complex with LMO4, supports mammary stem cells by directly targeting the Fgfr2 (show FGFR2 ELISA Kits) promoter in basal cells to increase its expression
Existence of a region in the lateral portion of the mammalian cochlea that is competent to make an organ of Corti is demonstrated in the absence of LMO4 function.
Low LMO4 mRNA levels were associated with response to erlotinib in non-small-cell lung cancer.
oncoprotein HBXIP (show HBXIP ELISA Kits) is able to activate the transcriptional coregulatory protein LMO4 through transcription factor Sp1 (show SP1 ELISA Kits) in promotion of proliferation of breast cancer cells.
Data suggest that overexpression of LMO4 may disrupt some of the normal tumour suppressor activities of CtIP (show RBBP8 ELISA Kits), thereby contributing to breast cancer progression.
the association of high levels of LMO4 with aggressive neuroblastomas is dependent on LMO4 regulation of cadherin expression and hence, tumor invasiveness
LMO4 is a direct target of p53 (show TP53 ELISA Kits) and inhibits p53 (show TP53 ELISA Kits)-mediated proliferative inhibition of breast cancer cells through interacting p53 (show TP53 ELISA Kits)
LMO4 is over-expressed in highly invasive rhabdomyosarcoma, alveolar cells
These results reveal a novel, LMO4-dependent transcriptional program within the basolateral amygdala that is essential to cue-reward learning.
activation of SLK (show SLK ELISA Kits) by haptotactic signals requires its recruitment to the leading edge by LMO4 in a Src (show SRC ELISA Kits)-dependent manner.
Thus, our study reveals an essential requirement for LMO4 to modulate central insulin (show INS ELISA Kits) signaling.
A novel sensory competent region in the lateral cochlear duct is regulated by LMO4.
By increasing neuronal activity in the paraventricular hypothalamus, food intake was suppressed in LMO4-deficient mice.
LMO4 is a novel modulator of adipogenesis.
The results of this study found that LIM domain only 4 (LMO4) inhibits PTP1B (show PTPN1 ELISA Kits) activity by increasing the oxidized inactive form of PTP1B (show PTPN1 ELISA Kits) in hypothalamus of mice.
results identify Lmo4 as a central developmental control over the diversity of motor cortex projection neuron subpopulations, establishing their area-specific identity and specialized connectivity.
LMO4 modulates the activity of the DEAF NES (show NES ELISA Kits), causing nuclear accumulation of a construct containing the LMO4-interaction region of DEAF1 (show DEAF1 ELISA Kits).
a selective role for LMO4 in the basolateral complex in modulating learned but not unlearned fear
This gene encodes a cysteine-rich protein that contains two LIM domains but lacks a DNA-binding homeodomain. The encoded protein may play a role as a transcriptional regulator or as an oncogene.
LIM domain only 4
, LIM domain only protein 4
, LIM domain transcription factor LMO4
, breast tumor autoantigen
, ethanol induced 4