anti-LIM Domain and Actin Binding 1 (LIMA1) Antibodies

LIMA1 encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. Additionally we are shipping LIMA1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LIMA1 300228  
LIMA1 51474 Q9UHB6
LIMA1 65970 Q9ERG0
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Top anti-LIMA1 Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Horse Rabbit Un-conjugated WB Host: Rabbit <br /> Target Name: LIMA1 <br /> Sample Tissue: Human Fetal Heart <br /> Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-LIMA1 Antibody Titration: 1.0 ug/ml Positive Control: COLO205 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of LIMA1 Antibody (N-term) in A549 cell line lysates (35ug/lane). This demonstrates the LIMA1 antibody detected the LIMA1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IP Detection of Human EPLIN by Immunoprecipitation. Samples: Whole cell lysate (500 mcg) from DU145 cells. Antibodies: Affinity purified rabbit anti-EPLIN antibody ABIN250691 used at 10 mcg/mg lysate for IP. Detection: Chemiluminescence with an exposure time of 30 seconds. 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: EPLIN Antibody [NBP1-87947] - Staining of human cell line U-2 OS shows positivity in plasma membrane, cytoplasm & cytoskeleton (actin filaments). Western Blot: EPLIN Antibody [NBP1-87947] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IP, IHC, WB Detection of Human EPLIN by Western Blot. Samples: A) Whole cell lysate (50 mcg) from DU145 and SKBR3 cells. B) EPLIN that was immunoprecipitated from 500 mcg of whole cell lysate from DU145 cells. Antibodies: Affinity purified rabbit anti-EPLIN antibody ABIN151503 was used at 0.3 mcg/ml (A) or 1 mcg/ml (B) for WB. In B, EPLIN was immunoprecipitated using another rabbit anti-EPLIN antibody. Detection: Chemiluminescence with exposure times of 30 minutes (A) or 30 seconds (B). Western Blot: EPLIN Antibody  - Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from MCF7 cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-EPLIN antibody (lot was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Log in to see 7 to 9 Days
$486.94
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Horse Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB LIMA1 Antibody (N-term)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the LIMA1 antibody detected the LIMA1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details

LIMA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human , ,
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Mouse (Murine) ,


Top referenced anti-LIMA1 Antibodies

  1. Human Polyclonal LIMA1 Primary Antibody for IP, IHC - ABIN250686 : Han, Kosako, Watanabe, Hattori: Extracellular signal-regulated kinase/mitogen-activated protein kinase regulates actin organization and cell motility by phosphorylating the actin cross-linking protein EPLIN. in Molecular and cellular biology 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal LIMA1 Primary Antibody for ICC, IF - ABIN4308788 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal LIMA1 Primary Antibody for IP - ABIN250691 : Zhang, Wang, Iqbal, Wang, Osunkoya, Chen, Chen, Shin, Yuan, Wang, Zhau, Chung, Ritenour, Kucuk, Wu: Epidermal growth factor promotes protein degradation of epithelial protein lost in neoplasm (EPLIN), a putative metastasis suppressor, during epithelial-mesenchymal transition. in The Journal of biological chemistry 2013 (PubMed)

  4. Cow (Bovine) Polyclonal LIMA1 Primary Antibody for WB - ABIN2775866 : Maul, Song, Amann, Gerbin, Pollard, Chang: EPLIN regulates actin dynamics by cross-linking and stabilizing filaments. in The Journal of cell biology 2003 (PubMed)

More Antibodies against LIMA1 Interaction Partners

Human LIM Domain and Actin Binding 1 (LIMA1) interaction partners

  1. Data provide evidence that downregulation of EPLIN-alpha may be associated with poor prognosis for patients with epithelial ovarian cancer (EOC), and that this molecule appears to play a tumour suppressor role by inhibition of EOC growth and migration.

  2. EPLIN is functionally linked to molecules like actin and paxillin (show PXN Antibodies) and has been implicated in a number of potential pathways to enhance metastatic potential

  3. a major activity of DNp73 is to establish initiation of the invasion-metastasis cascade via EPLIN-dependent IGF1R (show IGF1R Antibodies) regulation

  4. EGF (show EGF Antibodies) promotes epithelial-mesenchymal transition and induces degradation of EPLIN, a putative suppressor of prostate cancer metastasis.

  5. Together with the findings that EPLIN-alpha inhibits cellular growth and invasion, we conclude that EPLIN-alpha is a tumour suppressor of oesophageal cancer

  6. EPLIN clutch is necessary for stabilization of capillary structures in an angiogenesis model.

  7. EPLIN downregulation promotes epithelial-mesenchymal transition in prostate cancer cells and correlates with clinical lymph node metastasis.

  8. EPLIN functions to link the cadherin-catenin complex to F-actin and simultaneously stabilizes this population of actin fibers, resulting in the establishment of the adhesion

  9. expression of EPLIN-alpha in breast cancer is down-regulated in breast cancer cells .

  10. EPLIN protein may function during cytokinesis to maintain local accumulation of key cytokinesis proteins at the furrow.

Mouse (Murine) LIM Domain and Actin Binding 1 (LIMA1) interaction partners

  1. findings suggest that PINCH-1 (show LIMS1 Antibodies) regulates integrin-mediated adhesion of keratinocytes through the interactions with ILK (show ILK Antibodies) as well as EPLIN.

  2. Eplin-alpha transcription is regulated by actin-MAL-SRF signalling.

  3. EPLIN may function in growth control by associating with and regulating the actin cytoskeleton

  4. ERK-mediated phosphorylation of EPLIN contributes to actin filament reorganization and enhanced cell motility.

  5. EPLIN functions to link the cadherin-catenin complex to F-actin and simultaneously stabilizes this population of actin fibers, resulting in the establishment of the adhesion

LIMA1 Antigen Profile

Protein Summary

This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated.

Gene names and symbols associated with LIMA1

  • LIM domain and actin binding 1 (Lima1) antibody
  • LIM domain and actin binding 1 (LIMA1) antibody
  • LIM domain and actin binding 1 (lima1) antibody
  • 1110021C24Rik antibody
  • 3526402A12Rik antibody
  • D15Ertd366e antibody
  • Eplin antibody
  • LIMA1 antibody
  • MGC146397 antibody
  • SREBP3 antibody

Protein level used designations for LIMA1

LIM domain and actin-binding protein 1 , epithelial protein lost in neoplasm , LIM domain and actin binding 1 , epithelial protein lost in neoplasm beta , 1110021C24Rik , sterol regulatory element binding protein 3 , epithelial protein lost in neoplasm-a , epithelial protein lost in neoplasm-b , mEPLIN

GENE ID SPECIES
300228 Rattus norvegicus
451892 Pan troglodytes
779798 Xenopus (Silurana) tropicalis
51474 Homo sapiens
65970 Mus musculus
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