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LIM Homeobox Transcription Factor 1, alpha Proteins (LMX1A)

LMX1A encodes a homeodomain and LIM-domain containing protein. Additionally we are shipping LMX1A Antibodies (42) and LMX1A Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LMX1A 110648 Q9JKU8
Rat LMX1A LMX1A 289201  
LMX1A 4009 Q8TE12
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Top LMX1A Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

LMX1A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for LIM Homeobox Transcription Factor 1, alpha (LMX1A) Interaction Partners

Mouse (Murine) LIM Homeobox Transcription Factor 1, alpha (LMX1A) interaction partners

  1. This study showed that spontaneous Lmx1a mutations causing cerebellar pathology are impaired in motor functions during the neonatal period.

  2. The data of this study that Oc-1 (show ONECUT1 Proteins) interacts with Lmx1a to promote ventral midbrain neural stem cells differentiation into dopamine neuron through Wnt1 (show WNT1 Proteins)-Lmx1a pathway.

  3. Lmx1a signaling in mouse embryonic stem cells contributes to a molecular cascade establishing neuronal specification.

  4. our data demonstrate that key midbrain dopamine regulators (Nurr1 (show NR4A2 Proteins), Pitx3 (show PITX3 Proteins), and Lmx1a) play overlapping as well as distinct roles during neurogenesis and neurotransmitter phenotype determination of mDA neurons

  5. The data of this study suggested that aberrant anlage patterning and granule cell development lead to Purkinje cell ectopia, which ultimately causes abnormal cerebellar architecture in dreher.

  6. dopamine transporter is a direct target of Lmx1a and emphasizes a novel role of Lmx1a as one of regulators of mature midbrain dopaminergic neurotransmitter phenotypes

  7. Lmx1a mutant (dr/dr) embryos demonstrate a clear decrease in expression of the genes Grb10 (show GRB10 Proteins) and Rgs4 (show RGS4 Proteins).

  8. The characterization of two new Lmx1a alleles highlights the critical role of this gene in the development of the cochlea and vestibular system.

  9. Data conclude that Lmx1a is a useful marker for the extraction of progenitors of GABAergic or dopaminergic neurons.

  10. The Lmx1a can induce desired neuronal lineages from most expressing neural progenitor cells by a mechanism resembling developmental binary cell-fate switching.

Human LIM Homeobox Transcription Factor 1, alpha (LMX1A) interaction partners

  1. Lmx1a and Lmx1b (show LMX1B Proteins) expression persists in mature dopaminergic neurons of the substantia nigra pars (show EPRS Proteins) compacta and the ventral tegmental area. [Review]

  2. SNPs of the LMX1A gene might be associated with the susceptibility to congenital scoliosis and different clinical phenotypes in the Chinese Han population.

  3. To our best knowledge, this is the first report demonstrating the application of TAT (show TAT Proteins)-LMX1A recombinant protein to enhance hESC differentiation to DA as shown by the expression of DA specific makers.

  4. LMX1A is weakly methylated in cervical adenocarcinomas compared with controls, in a metastatic stage of cervical cancer.

  5. these data imply that Sp1 (show PSG1 Proteins) and EZH2 (show EZH2 Proteins) may activate LMX1A expression upon oncogenic stress during cervical cancer development.

  6. Higher immunostaining intensity for OPN (show SPP1 Proteins) and LMX1A correlated with WHO grades for meningiomas and some gliomas. Contrary to our expectations, LMX1A staining in WHO grade IV gliomas was shown to be weaker than in WHO grade III tumours.

  7. The Lmx1a can induce desired neuronal lineages from most expressing neural progenitor cells by a mechanism resembling developmental binary cell-fate switching.

  8. One single nucleotide polymorphisms of lmx1a was strongly associated with the magnitude of training-related gains in verbal working memory

  9. LMX1A may be a potential biomarker for gastric cancer.

  10. Genetic variation in LMX1A may increase the risk of developing schizophrenia.

LMX1A Protein Profile

Protein Summary

This gene encodes a homeodomain and LIM-domain containing protein. The encoded protein is a transcription factor that acts as a positive regulator of insulin gene transcription. This gene also plays a role in the development of dopamine producing neurons during embryogenesis. Mutations in this gene are associated with an increased risk of developing Parkinson's disease. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with LMX1A

  • LIM homeobox transcription factor 1 alpha (Lmx1a)
  • LIM homeobox transcription factor 1, alpha (LMX1A)
  • LIM homeobox transcription factor 1, alpha (lmx1a)
  • dr protein
  • dreher protein
  • LMX1 protein
  • LMX1.1 protein
  • si:ch211-260g14.3 protein
  • sst protein

Protein level used designations for LMX1A

LIM homeobox transcription factor 1-alpha , LIM/homeobox protein 1.1 , LIM/homeobox protein LMX1A , LMX-1.1 , shaker short-tail

GENE ID SPECIES
110648 Mus musculus
289201 Rattus norvegicus
4009 Homo sapiens
558036 Danio rerio
777133 Gallus gallus
609061 Canis lupus familiaris
510296 Bos taurus
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