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LASP1 encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. Additionally we are shipping LASP1 Proteins (16) and LASP1 Kits (11) and many more products for this protein.
Showing 10 out of 112 products:
Human Polyclonal LASP1 Primary Antibody for ELISA, WB - ABIN4330346
Schreiber, Moog-Lutz, Régnier, Chenard, Boeuf, Vonesch, Tomasetto, Rio: Lasp-1, a novel type of actin-binding protein accumulating in cell membrane extensions. in Molecular medicine (Cambridge, Mass.) 1999
Human Polyclonal LASP1 Primary Antibody for ICC, IF - ABIN4330347
Ngan, Northey, Brown, Ursini-Siegel, Siegel: A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells. in Journal of cell science 2013
Human Polyclonal LASP1 Primary Antibody for ELISA, IHC (p) - ABIN262290
Grunewald, Kammerer, Schulze, Schindler, Honig, Zimmer, Butt: Silencing of LASP-1 influences zyxin localization, inhibits proliferation and reduces migration in breast cancer cells. in Experimental cell research 2006
Cow (Bovine) Polyclonal LASP1 Primary Antibody for WB - ABIN2785890
Stone, Merriman, Cantor, Geschwind, Nelson: High density SNP association study of a major autism linkage region on chromosome 17. in Human molecular genetics 2007
The correlation between LIM (show PDLIM5 Antibodies) and SH3 domain-containing protein (show PEX13 Antibodies) expression levels in cancer and the poor outcome and metastatic behavior of tumors denotes the clinical significance of this protein and hints its potential value as a new cancer prognostic or even diagnostic biomarker
LASP-1 contributes to the formation and progression of prostate cancer through a NF-kappaappa B pathway.
LASP-1 may essentially involve in the metastasis and growth of CCA (show FBN2 Antibodies) and clinical significance of LASP-1 may reside in function as a biomarker to predict prognosis and as a promising therapeutic strategy for CCA (show FBN2 Antibodies) patients by the inhibition of LASP-1 expression
It is a target gene of miR-1.
LASP-1 associated with UHRF1 (show UHRF1 Antibodies), G9a (show EHMT2 Antibodies), Snail1 (show SNAI1 Antibodies) and di- and tri (show VANGL2 Antibodies)-methylated histoneH3 in a CXCL12 (show CXCL12 Antibodies)-dependent manner based on immunoprecipitation and proximity ligation assays
LASP-1 induces proliferation, metastasis and cell cycle arrest at the G2/M phase in gallbladder cancer by down-regulating S100P (show S100P Antibodies) via the PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) pathway.
LASP-1, mediated by miR (show MLXIP Antibodies)-203, has crucial functions in the proliferation, migration and invasion of human non-small cell lung cancer
Detecting an affection of migratory processes after LASP-1 silencing, we propose that LASP-1 could impact on metastasis of CC [choriocarcinoma]cells.
Results identified LASP1 as a hitherto unknown protein in melanocytes and as novel partner of dynamin (show DNM1 Antibodies) in the physiological process of membrane constriction and melanosome vesicle release.
Our results suggest that LASP-1 mRNA overexpression may be mainly implicated in female hepatocellular carcinoma (HCC (show FAM126A Antibodies)) and cirrhotic HCCs (show HCCS Antibodies); and that LASP1 may play its role with vimentin (show VIM Antibodies) in HCC (show FAM126A Antibodies) cells.
Results defined LASP1 as a direct target gene for HIF1alpha (show HIF1A Antibodies) upregulation that is critical for metastatic progression of PDAC.
Data show that MEFs derived from Lasp1(-/-) mice migrated more rapidly in vitro.
LIM-nebulette (show NEBL Antibodies), Lasp-1, and zyxin (show ZYX Antibodies) may play an important role in the organization of focal adhesions
Lasp-1 is a dynamic focal adhesion protein necessary for cell migration and survival in response to growth factors and ECM (show MMRN1 Antibodies) proteins.
Data suggest that there are no functional differences between human and mouse LASP-1.
The role of Lasp1 in the regulation of hydrochloride secretion in vivo was studied in a murine model with a targeted disruption of the Lasp-1 gene.
role of Lasp1 in chondrocyte differentiation during cartilage to bone transition
This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.
LIM and SH3 domain protein 1
, LIM and SH3 protein 1
, lasp1 protein
, metastatic lymph node gene 50 protein
, MLN 50
, 40 kDa phosphoprotein
, phosphoprotein Lasp-1