anti-LIM and SH3 Protein 1 (LASP1) Antibodies

LASP1 encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. Additionally we are shipping LASP1 Proteins (16) and LASP1 Kits (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LASP1 3927 Q14847
LASP1 16796 Q61792
LASP1 29278 Q99MZ8
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Top anti-LASP1 Antibodies at antibodies-online.com

Showing 10 out of 112 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-LASP1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:2500 Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB Rabbit Anti-LASP1 Antibody Catalog Number: ARP54798_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: N/A Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec WB Suggested Anti-LASP1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: HepG2 cell lysate LASP1 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Anti-LASP1 antibody,  Western blotting Lane 1: HELA Cell Lysate Lane 2: MCF-7 Cell Lysate Anti-LASP1 antibody, ICC ICC: A549 Cell 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of LASP1 Antibody (Center) in A549 cell line lysates (35ug/lane). This demonstrates the LASP1 antibody detected the LASP1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB ABIN184658 staining (0.1µg/ml) of Human Brain (Cerebellum) extracts (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Dog Goat Un-conjugated WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Mouse Un-conjugated WB Western Blot analysis of LASP1 expression in transfected 293T cell line by LASP1 monoclonal antibody (M05), clone 4F5. Lane 1: LASP1 transfected lysate(29.7 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Cow Rabbit Un-conjugated WB   200 μL Log in to see 13 to 14 Days
$487.50
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details

LASP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-LASP1 Antibodies

  1. Human Polyclonal LASP1 Primary Antibody for ELISA, WB - ABIN4330346 : Schreiber, Moog-Lutz, Régnier, Chenard, Boeuf, Vonesch, Tomasetto, Rio: Lasp-1, a novel type of actin-binding protein accumulating in cell membrane extensions. in Molecular medicine (Cambridge, Mass.) 1999 (PubMed)

  2. Human Polyclonal LASP1 Primary Antibody for ICC, IF - ABIN4330347 : Ngan, Northey, Brown, Ursini-Siegel, Siegel: A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells. in Journal of cell science 2013 (PubMed)

  3. Human Polyclonal LASP1 Primary Antibody for ELISA, IHC (p) - ABIN262290 : Grunewald, Kammerer, Schulze, Schindler, Honig, Zimmer, Butt: Silencing of LASP-1 influences zyxin localization, inhibits proliferation and reduces migration in breast cancer cells. in Experimental cell research 2006 (PubMed)

  4. Cow (Bovine) Polyclonal LASP1 Primary Antibody for WB - ABIN2785890 : Stone, Merriman, Cantor, Geschwind, Nelson: High density SNP association study of a major autism linkage region on chromosome 17. in Human molecular genetics 2007 (PubMed)

More Antibodies against LASP1 Interaction Partners

Human LIM and SH3 Protein 1 (LASP1) interaction partners

  1. The correlation between LIM (show PDLIM5 Antibodies) and SH3 domain-containing protein (show PEX13 Antibodies) expression levels in cancer and the poor outcome and metastatic behavior of tumors denotes the clinical significance of this protein and hints its potential value as a new cancer prognostic or even diagnostic biomarker

  2. LASP-1 contributes to the formation and progression of prostate cancer through a NF-kappaappa B pathway.

  3. LASP-1 may essentially involve in the metastasis and growth of CCA (show FBN2 Antibodies) and clinical significance of LASP-1 may reside in function as a biomarker to predict prognosis and as a promising therapeutic strategy for CCA (show FBN2 Antibodies) patients by the inhibition of LASP-1 expression

  4. It is a target gene of miR-1.

  5. LASP-1 associated with UHRF1 (show UHRF1 Antibodies), G9a (show EHMT2 Antibodies), Snail1 (show SNAI1 Antibodies) and di- and tri (show VANGL2 Antibodies)-methylated histoneH3 in a CXCL12 (show CXCL12 Antibodies)-dependent manner based on immunoprecipitation and proximity ligation assays

  6. LASP-1 induces proliferation, metastasis and cell cycle arrest at the G2/M phase in gallbladder cancer by down-regulating S100P (show S100P Antibodies) via the PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) pathway.

  7. LASP-1, mediated by miR (show MLXIP Antibodies)-203, has crucial functions in the proliferation, migration and invasion of human non-small cell lung cancer

  8. Detecting an affection of migratory processes after LASP-1 silencing, we propose that LASP-1 could impact on metastasis of CC [choriocarcinoma]cells.

  9. Results identified LASP1 as a hitherto unknown protein in melanocytes and as novel partner of dynamin (show DNM1 Antibodies) in the physiological process of membrane constriction and melanosome vesicle release.

  10. Our results suggest that LASP-1 mRNA overexpression may be mainly implicated in female hepatocellular carcinoma (HCC (show FAM126A Antibodies)) and cirrhotic HCCs (show HCCS Antibodies); and that LASP1 may play its role with vimentin (show VIM Antibodies) in HCC (show FAM126A Antibodies) cells.

Mouse (Murine) LIM and SH3 Protein 1 (LASP1) interaction partners

  1. Results defined LASP1 as a direct target gene for HIF1alpha (show HIF1A Antibodies) upregulation that is critical for metastatic progression of PDAC.

  2. Data show that MEFs derived from Lasp1(-/-) mice migrated more rapidly in vitro.

  3. LIM-nebulette (show NEBL Antibodies), Lasp-1, and zyxin (show ZYX Antibodies) may play an important role in the organization of focal adhesions

  4. Lasp-1 is a dynamic focal adhesion protein necessary for cell migration and survival in response to growth factors and ECM (show MMRN1 Antibodies) proteins.

  5. Data suggest that there are no functional differences between human and mouse LASP-1.

  6. The role of Lasp1 in the regulation of hydrochloride secretion in vivo was studied in a murine model with a targeted disruption of the Lasp-1 gene.

  7. role of Lasp1 in chondrocyte differentiation during cartilage to bone transition

LASP1 Antigen Profile

Protein Summary

This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.

Gene names and symbols associated with LASP1

  • LIM and SH3 domain protein 1 (lasp1) antibody
  • LIM and SH3 protein 1 (lasp1) antibody
  • LIM and SH3 protein 1 (LASP1) antibody
  • lasp1 protein (lasp1) antibody
  • LIM and SH3 protein 1 (Lasp1) antibody
  • AA408629 antibody
  • Def-4 antibody
  • fb92f05 antibody
  • lasp-1 antibody
  • LASP1 antibody
  • MGC53336 antibody
  • MGC89667 antibody
  • mln50 antibody
  • SH3P6 antibody
  • Tg(Col1a1-lacZ)1Ngma antibody
  • wu:fb92f05 antibody
  • zgc:77542 antibody

Protein level used designations for LASP1

LIM and SH3 domain protein 1 , LIM and SH3 protein 1 , lasp1 protein , metastatic lymph node gene 50 protein , LASP-1 , MLN 50 , Tg(11Col1a1)NG , 40 kDa phosphoprotein , phosphoprotein Lasp-1 , pp40

GENE ID SPECIES
100195513 Salmo salar
380354 Xenopus laevis
454620 Pan troglodytes
493322 Xenopus (Silurana) tropicalis
694950 Macaca mulatta
420002 Gallus gallus
3927 Homo sapiens
16796 Mus musculus
29278 Rattus norvegicus
608624 Canis lupus familiaris
323216 Danio rerio
495167 Xenopus laevis
532851 Bos taurus
100009568 Oryctolagus cuniculus
100173670 Pongo abelii
Selected quality suppliers for anti-LASP1 (LASP1) Antibodies
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