You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-LPS-Responsive Vesicle Trafficking, Beach and Anchor Containing (LRBA) Antibodies

The protein encoded by LRBA is a member of the WDL-BEACH-WD (WBW) gene family. Additionally we are shipping LRBA Kits (2) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse LRBA LRBA 80877 Q9ESE1
LRBA 987 P50851
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-LRBA Antibodies at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Rabbit FITC ELISA, WB 100 μg Log in to see 9 to 11 Days
$328.90
Details
Human Rabbit FITC ELISA, WB 100 μg Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Biotin ELISA, WB 100 μg Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit HRP ELISA, WB 100 μg Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Biotin ELISA, WB 100 μg Log in to see 16 to 21 Days
$427.14
Details
Human Rabbit FITC ELISA, WB 100 μg Log in to see 16 to 21 Days
$427.14
Details
Human Rabbit HRP ELISA, WB 100 μg Log in to see 16 to 21 Days
$427.14
Details
Human Rabbit FITC 100 μg Log in to see 9 to 19 Days
$432.73
Details
Human Rabbit Biotin 100 μg Log in to see 9 to 19 Days
$432.73
Details
Human Rabbit HRP 100 μg Log in to see 9 to 19 Days
$432.73
Details

LRBA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human


, ,

More Antibodies against LRBA Interaction Partners

Human LPS-Responsive Vesicle Trafficking, Beach and Anchor Containing (LRBA) interaction partners

  1. diagnosis of LRBA deficiency was confirmed by a fluorescence-activated cell sorting-based immunoassay

  2. Variants of LRBA were associated with common variable immunodeficiency.

  3. A homozygous missense mutation in lipopolysaccharide-responsive and beige (show LYST Antibodies)-like anchor gene is associated with inflammatory bowel disease.

  4. LRBA mutation was associated with an autoimmune lymphoproliferative syndrome-like disease characterized by splenomegaly and lymphadenopathy, cytopenia, elevated double negative T cells and raised serum Fas ligand (show FASL Antibodies) levels.

  5. Patients with LRBA deficiency manifested a dramatic and sustained improvement in response to abatacept, a CTLA4 (cytotoxic T lymphocyte antigen-4 (show CTLA4 Antibodies))-immunoglobulin fusion drug.

  6. LRBA deficiency is a novel cause of immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX (show FOXP3 Antibodies)) syndrome and Treg cell deficiency associated with metabolic dysfunction and increased apoptosis of Treg cells.

  7. A truncating mutation in LRBA, which abolished protein expression, was identified as the most likely candidate in a consanguineous family with chronic inflammatory bowel disease-like disorder and combined immunodeficiency.

  8. mutations in LRBA cause an immune deficiency characterized by defects in B cell activation (show BLNK Antibodies) and autophagy and by susceptibility to apoptosis, associated with a clinical phenotype of hypogammaglobulinemia and autoimmunity

  9. The crystal structure of the aPH (show APEH Antibodies)-BEACH domains of LRBA were studied.

LRBA Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LRBA

  • LPS-responsive beige-like anchor (Lrba) antibody
  • LPS-responsive vesicle trafficking, beach and anchor containing (LRBA) antibody
  • BGL antibody
  • C80285 antibody
  • CDC4L antibody
  • CVID8 antibody
  • D3Ertd775e antibody
  • LAB300 antibody
  • LBA antibody

Protein level used designations for LRBA

beige-like protein , lipopolysaccharide-responsive and beige-like anchor protein , CDC4-like protein , vesicle trafficking, beach and anchor containing

GENE ID SPECIES
80877 Mus musculus
987 Homo sapiens
Selected quality suppliers for anti-LRBA (LRBA) Antibodies
Did you look for something else?