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LPS-Responsive Vesicle Trafficking, Beach and Anchor Containing (LRBA) ELISA Kits

The protein encoded by LRBA is a member of the WDL-BEACH-WD (WBW) gene family. Additionally we are shipping LRBA Antibodies (16) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
LRBA 80877 Q9ESE1
LRBA 987 P50851
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Top LRBA ELISA Kits at

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 31.25 pg/ml 125-8000 pg/mL 96 Tests Log in to see 11 to 13 Days
Mouse 7.81 pg/ml 31.25-2000 pg/mL 96 Tests Log in to see 11 to 13 Days

More ELISA Kits for LRBA Interaction Partners

Human LPS-Responsive Vesicle Trafficking, Beach and Anchor Containing (LRBA) interaction partners

  1. diagnosis of LRBA deficiency was confirmed by a fluorescence-activated cell sorting-based immunoassay

  2. Variants of LRBA were associated with common variable immunodeficiency.

  3. A homozygous missense mutation in lipopolysaccharide-responsive and beige (show LYST ELISA Kits)-like anchor gene is associated with inflammatory bowel disease.

  4. LRBA mutation was associated with an autoimmune lymphoproliferative syndrome-like disease characterized by splenomegaly and lymphadenopathy, cytopenia, elevated double negative T cells and raised serum Fas ligand (show FASL ELISA Kits) levels.

  5. Patients with LRBA deficiency manifested a dramatic and sustained improvement in response to abatacept, a CTLA4 (cytotoxic T lymphocyte antigen-4 (show CTLA4 ELISA Kits))-immunoglobulin fusion drug.

  6. LRBA deficiency is a novel cause of immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX (show FOXP3 ELISA Kits)) syndrome and Treg cell deficiency associated with metabolic dysfunction and increased apoptosis of Treg cells.

  7. A truncating mutation in LRBA, which abolished protein expression, was identified as the most likely candidate in a consanguineous family with chronic inflammatory bowel disease-like disorder and combined immunodeficiency.

  8. mutations in LRBA cause an immune deficiency characterized by defects in B cell activation (show BLNK ELISA Kits) and autophagy and by susceptibility to apoptosis, associated with a clinical phenotype of hypogammaglobulinemia and autoimmunity

  9. The crystal structure of the aPH (show APEH ELISA Kits)-BEACH domains of LRBA were studied.

LRBA Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LRBA

  • LPS-responsive beige-like anchor (Lrba) antibody
  • LPS-responsive vesicle trafficking, beach and anchor containing (LRBA) antibody
  • BGL antibody
  • C80285 antibody
  • CDC4L antibody
  • CVID8 antibody
  • D3Ertd775e antibody
  • LAB300 antibody
  • LBA antibody

Protein level used designations for LRBA

beige-like protein , lipopolysaccharide-responsive and beige-like anchor protein , CDC4-like protein , vesicle trafficking, beach and anchor containing

80877 Mus musculus
987 Homo sapiens
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